Zobrazeno 1 - 10
of 24
pro vyhledávání: '"R. E. Walsh"'
Autor:
R. E. Walsh, G. K Crossman
Publikováno v:
BSAP Occasional Publication. 35:1-12
The sport horse industry in Great Britain is fragmented and serendipitous. However, there are many opportunities available for it to develop and grow. The research this paper is based upon was carried out in conjunction with British Breeding, to impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b40728810832d15160089dd074e8d738
https://doi.org/10.1017/s0263967x00042543
https://doi.org/10.1017/s0263967x00042543
Autor:
D. J. Fretland, D. L. Widomski, Timothy S. Gaginella, James F. Kachur, T.J. Maziasz, C. P. Anglin, B.S. Tsai, Stella S. Yu, Tadimeti S. Rao, R. E. Walsh, R H Keith, Stephen H Docter, Stevan W. Djuric, D Villani-Price
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:811-816
The Structure Activity Relationship (SAR) studies leading to the identification of a novel high potency Leukotriene B4 receptor antagonist SC-53228 are delineated. This compound shows excelled pharmacodynamic efficacy in animal models of inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ae9db9d931f92a43a7315a6d0686fdb
https://doi.org/10.1016/s0960-894x(01)80853-2
https://doi.org/10.1016/s0960-894x(01)80853-2
Autor:
D. L. Widomski, Timothy S. Gaginella, R. E. Walsh, D. J. Fretland, C. P. Anglin, Stuart Levin
Publikováno v:
Journal of Leukocyte Biology. 49:283-288
The products of the 5- and 12-lipoxygenase (5-LO, 12-LO) pathways of arachidonic acid metabolism are implicated as proinflammatory mediators in a number of disease states. 12(R)-hydroxyeicosatetraenoic acid [12(R)-HETE] is present in large quantities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5a6f16183465b00a417935060de0fa7
https://doi.org/10.1002/jlb.49.3.283
https://doi.org/10.1002/jlb.49.3.283
Autor:
T. S. Gaginella, R. E. Walsh
Publikováno v:
Scandinavian Journal of Gastroenterology. 26:1217-1224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff57a807f5aa53b473200c3e3e4ab890
https://doi.org/10.3109/00365529108998617
https://doi.org/10.3109/00365529108998617
Autor:
B.S. Tsai, Stuart Levin, S. W. Djuric, J. M. Zemaitis, D. L. Widomski, Timothy S. Gaginella, R. E. Walsh, D. J. Fretland, R. L. Shone
Publikováno v:
Inflammation. 14:727-739
Neutrophil (PMNL) infiltration is a prominent feature of human psoriasis. Psoriatic skin lesions contain abnormally high amounts of leukotriene B4 (LTB4), itself a potent PMNL chemoattractant both in vivo and in vitro. SC-41930 (7-[3-(4-acetyl-3-meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126c942ddb80468af6a4899e688b971c
https://doi.org/10.1007/bf00916375
https://doi.org/10.1007/bf00916375
Publikováno v:
Pharmacy practice management quarterly. 19(2)
Aprotinin, a naturally occurring protease inhibitor derived from bovine lung, is used prophylactically to minimize the amount of perioperative blood loss in patients undergoing coronary artery bypass graft surgery who are at high risk for excessive b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5529071d0cb6aacdcc2da20f8b3d039b
https://pubmed.ncbi.nlm.nih.gov/10558092
https://pubmed.ncbi.nlm.nih.gov/10558092
Autor:
B S, Tsai, R H, Keith, W E, Perkins, R E, Walsh, C P, Anglin, P W, Collins, A W, Gasiecki, R F, Bauer, P H, Jones, T S, Gaginella
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 275(1)
Prostaglandins (PGs) in the E-series exhibit potent gastric antisecretory activity, but can also cause diarrhea, which is mediated via PGE receptors. SC-46275, an omega-chain cyclopentenyl analog of the E-type PG enisoprost, was evaluated with other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c4ab637c2c25d71a5c5de327ef276d2
https://pubmed.ncbi.nlm.nih.gov/7562572
https://pubmed.ncbi.nlm.nih.gov/7562572
Autor:
Marsha A. Henke, D. L. Widomski, Neal K. Clapp, C. P. Anglin, R. M. Hansard, R. E. Walsh, D. J. Fretland, Richard E. Carson
Publikováno v:
Agents and actions.
Use of the CTT model provides insight into the inflammatory mediator contribution in the pathogenesis of idiopathic colitis. To evaluate anti-colitic efficacy, the leukotriene B4 receptor antagonist and anti-inflammatory agent, SC-41930, was administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01738d6a2ffa5c89ed849a6b7d71e53d
https://pubmed.ncbi.nlm.nih.gov/8273593
https://pubmed.ncbi.nlm.nih.gov/8273593
Autor:
R. E. Walsh, Stuart Levin, C. P. Anglin, D. J. Fretland, D. L. Widomski, A. F. Gasiecki, P. W. Collins
Publikováno v:
Inflammation. 16(6)
The mucosal protective prostaglandin analogs misoprostol, enisoprost, and SC-46275 (the 17E-18-cyclopentenyl analog of enisoprost) were tested in mouse and rat colitis induced by the intrarectal instillation of dilute acetic acid. Colitis was assesse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26ef70336587f1519303eb7333e17f4
https://pubmed.ncbi.nlm.nih.gov/1334049
https://pubmed.ncbi.nlm.nih.gov/1334049