Zobrazeno 1 - 10
of 14
pro vyhledávání: '"R. E. S. Bullingham"'
Publikováno v:
Acta Anaesthesiologica Scandinavica. 43:1041-1046
Background: Previous pharmacokinetic studies on racemic ketorolac using nonstereoselective analytical methods have indicated that the plasma clearance of ketorolac is higher and the volume of distribution greater in children than in adults. The aim o
Publikováno v:
British journal of anaesthesia. 67(3)
The morphine sparing effect of ketorolac 10 mg administered 4-hourly by intermittent i.m. injection was compared with a continuous i.m. infusion in a double-blind, placebo-controlled trial in patients undergoing upper abdominal surgery. During the 48
Autor:
R. E. S. Bullingham, H. Krimer
Publikováno v:
Survey of Anesthesiology. 37:194
Publikováno v:
Automatica. 21:349-360
The paper arises from collaborative work to explore contributions which the technology of control engineering can make to pain relief. One particular demand analgesia system was studied in which Fentanyl was intravenously infused to relieve pain duri
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 21:125-130
A method is described for the measurement of morphine in human plasma by ion-paired reverse-phase liquid chromatography. It includes a novel solid-phase extraction of morphine from plasma which is simple, rapid and complete. No known morphine metabol
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 21:318-325
Analysis of morphine in plasma by radioimmunoassay is complicated by interference from morphine metabolites, particularly morphine-3-glucuronide. This interference makes radioimmunoassay a poor technique to study the pharmacokinetics of morphine in m
Publikováno v:
Anaesthesia. 39:987-995
The use of the pH radio pill for the assessment of antacid effect has been evaluated. The correlation between the pH pill and a conventional pH electrode system was high (r2 = 0.997). The records of in vivo pH against time allow unique measurements o
Publikováno v:
Thrombosis and Haemostasis. 60:382-386
SummaryKetorolac is a potent cyclo-oxygenase inhibitor used for the treatment of postoperative pain. It is known to have anti-platelet properties. The aim of this study was to determine the effect of ketorolac on haemostasis both alone and in combina
Autor:
R. E. S. Bullingham
Publikováno v:
Drugs. 29:376-386
After surgery, patients try to minimise discomfort by various manoeuvres including change of posture, immobilisation of injured areas and use of analgesic drugs. The characteristic finding with drug use, revealed by permitting patients to titrate the
Autor:
R. E. S. Bullingham, G. M. O'sullivan
Publikováno v:
British journal of obstetrics and gynaecology. 91(10)
Summary. Non-invasive radiotelemetry techniques were used for the in-vivo assessment of gastric acidity and the effect of antacids in non-pregnant women and women in the third trimester of pregnancy. A particulate (magnesium trisilicate mixture) and