Zobrazeno 1 - 10
of 29
pro vyhledávání: '"R. E. Kazakov"'
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 24, Iss 3, Pp 322-334 (2024)
INTRODUCTION. The increasing prevalence of multidrug-resistant strains of pathogens determines the need for fundamentally new antibacterial agents, including bacteriophage preparations. The consistent implementation of phage therapy is hindered by th
Externí odkaz:
https://doaj.org/article/0bf70e1098f740fd9bef807080ca49d8
Autor:
R. E. Kazakov, G. I. Gorodetskaya, R. V. Archvadze, A. V. Zavtonev, A. V. Danilov, D. L. Fetlam, D. A. Ishalev, N. G. Berdnikova, E. Yu. Demchenkova
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 4, Pp 531-539 (2023)
Scientist relevance. Antibacterials can have nephrotoxic effects because medicinal products of this class are primarily excreted by the kidneys.Aim. The study aimed to analyse literature data on the mechanisms, risk factors and specific features of t
Externí odkaz:
https://doaj.org/article/ba03043d52f3418f89adc648076fc97d
Autor:
A. B. Prokofiev, S. A. Belkov, R. E. Kazakov, N. G. Berdnikova, T. A. Rodina, E. S. Melnikov, A. A. Danko, N. E. Voronova, R. Z. Vafina, A. V. Zavtoniev, D. V. Tsyganko, E. Yu. Demchenkova
Publikováno v:
Безопасность и риск фармакотерапии, Vol 10, Iss 2, Pp 139-150 (2022)
Vancomycin is prescribed to patients in serious condition with infections caused by Gram-positive microorganisms; however, if the therapeutic plasma concentration of the medicinal product is exceeded, it can have a nephrotoxic effect.The aim of the s
Externí odkaz:
https://doaj.org/article/5d1b56ee56e245b2b4c7c0353cff62ad
Autor:
S. Yu. Serebrova, A. B. Prokofiev, M. V. Zhuravleva, R. E. Kazakov, I. V. Suchinava, G. I. Gorodetskaya, N. N. Eremenko, N. B. Lazareva, L. R. Galstyan, E. A. Smolyarchuk, D. O. Kurguzova, A. O. Barkov
Publikováno v:
Антибиотики и Химиотерапия, Vol 62, Iss 3-4, Pp 37-45 (2020)
The article highlights modern concepts of inflammatory diseases in adults and children in terms of genetic possibilities for diagnosing Crohn's disease and ulcerative colitis. It names the main candidate genes, which, in the presence of their specifi
Externí odkaz:
https://doaj.org/article/36cbbde1fb0f400c90071e571a0ff681
Publikováno v:
Андрология и генитальная хирургия, Vol 20, Iss 1, Pp 13-21 (2019)
The study objective is to present current data on various genetic reasons of feminization.Results. Disruption of puberty in males can be associated with genetically determined defects of androgen receptor which cause partial or full insensitivity to
Externí odkaz:
https://doaj.org/article/06fbd1f342864b6bb7cc21bdd85f99be
Publikováno v:
Безопасность и риск фармакотерапии, Vol 6, Iss 2, Pp 78-85 (2018)
This article describes basic information about the classification, structure, substrate specificity and expression of organic cation transporters. The pharmacokinetic and pharmacogenetic aspects of transporters are discussed in more detail, as well a
Externí odkaz:
https://doaj.org/article/25b536591303417dace1019884dbc22c
Publikováno v:
Безопасность и риск фармакотерапии, Vol 5, Iss 2, Pp 70-75 (2018)
This review article describes the classification and mechanism of action of organic anion transporters (OAT). The influence of certain members of this family of transporters on the pharmacokinetics of β-lactam antibiotics.
Externí odkaz:
https://doaj.org/article/db1b0b23406445ddbfe606fd9d476891
Autor:
G. I. Gorodetskaya, V. G. Kukes, S. A. Belkov, R. E. Kazakov, S. Yu. Serebrova, O. V. Muslimova, T. A. Rodina, A. A. Aleksandrov
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 7, Iss 4, Pp 233-241 (2018)
The article analyses scientific literature on the use of pharmacogenetic testing to optimize sulfonylurea treatment of patients with type 2 diabetes. It describes characteristics of modern sulfonylurea drugs used in the treatment of type 2 diabetes,
Externí odkaz:
https://doaj.org/article/58109646f10940ddbab20c0a634e87d2
Autor:
R. E. Kazakov, V. A. Evteev, O. V. Muslimova, I. A. Mazerkina, E. Yu. Demchenkova, E. V. Shikh
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 7, Iss 4, Pp 212-220 (2018)
The article reviews scientific literature on C3435T polymorphism in the ABCB1 gene which encodes P-glycoprotein (an ATP-binding cassette transporter which is responsible for energy-dependent transport of substrates across cellular membranes and whose
Externí odkaz:
https://doaj.org/article/3c1f621f3d514346b051cdcaecae239c
Publikováno v:
Сеченовский вестник, Vol 0, Iss 4, Pp 25-27 (2018)
The aim of the work is to study the functional characteristics of SLC transporters of organic anions: OAT1 and OAT3 in normal conditions and in model ischemia/reperfusion injury.Materials and methods. The HEK293 cell line was used as a model for the
Externí odkaz:
https://doaj.org/article/24e6b890128e4a3384029c2c3a29b3fe