Zobrazeno 1 - 10
of 104
pro vyhledávání: '"R. E. J. Mitchel"'
Publikováno v:
Dose-Response, Vol 13 (2015)
In February 2000, a radiation incident involving a medical 60 Co source occurred in a metal scrapyard in Thailand. Several individuals were suspected to have received chronic or fractionated exposures ranging from a few mGy to a several Gy. Using flu
Externí odkaz:
https://doaj.org/article/e56fa3398d394c108d95a922902c5e82
Autor:
R. E. J. Mitchel
Publikováno v:
Dose-Response, Vol 5 (2007)
The Linear No Threshold (LNT) hypothesis states that ionizing radiation risk is directly proportional to dose, without a threshold. This hypothesis, along with a number of additional derived or auxiliary concepts such as radiation and tissue type wei
Externí odkaz:
https://doaj.org/article/9799d99b96eb428c95b07f49ef78a998
Autor:
R. E. J. Mitchel
Publikováno v:
Dose-Response, Vol 5 (2007)
The “Linear No Threshold” hypothesis, used in all radiation protection practices, assumes that all doses, no matter how low, increase the risk of cancer, birth defects and heritable mutations. In vitro cell based experiments show adaptive process
Externí odkaz:
https://doaj.org/article/b122d572f2fe401eb8f5e5b911d6617c
Publikováno v:
Dose-Response, Vol 4 (2006)
There are a number of studies that show radiation can cause heritable mutations in the offspring of irradiated organisms. These “germ-line mutations” have been shown to occur in unique sequences of DNA called “minisatellite loci”. The high fr
Externí odkaz:
https://doaj.org/article/cab97136d013479c8603a8aef8c4690f
Autor:
R. E. J. Mitchel
Publikováno v:
Dose-Response, Vol 4 (2006)
Research reports using cells from bacteria, yeast, alga, nematodes, fish, plants, insects, amphibians, birds and mammals, including wild deer, rodents or humans show non-linear radio-adaptive processes in response to low doses of low LET radiation. L
Externí odkaz:
https://doaj.org/article/47797282ef944964988563076f0d6edd
Publikováno v:
Dose-Response, Vol 3 (2005)
A stochastic two-stage cancer model with clonal expansion was used to investigate the potential impact on human lung cancer incidence of some aspects of the hormesis mechanisms suggested by Feinendegen ( Health Phys. 52 663–669, 1987). The model wa
Externí odkaz:
https://doaj.org/article/58d219913f96461990a23e60b448b737
Autor:
R. E. J. Mitchel
Publikováno v:
Dose-Response, Vol 3 (2005)
Risk prediction and dose limits for human radiation exposure are based on the assumption that risk is proportional to total dose. However, there is concern about the appropriateness of those limits for people who may be genetically cancer prone. The
Externí odkaz:
https://doaj.org/article/5d1cf3b6a4cd46fb98d4f423c9bf94c7
Publikováno v:
Dose-Response, Vol 2 (2004)
A multistage cancer model that describes the putative rate-limiting steps in carcinogenesis is developed and used to investigate the potential impact on cumulative lung cancer incidence of the hormesis mechanisms suggested by Feinendegen and Pollycov
Externí odkaz:
https://doaj.org/article/a9f91b7701344b039023db32373d6af1
Autor:
R. E. J. Mitchel
Publikováno v:
Dose-Response, Vol 2 (2004)
The bystander effect refers to the biological response of a cell resulting from an event in an adjacent or nearby cell. Such effects depend on intercellular communication and amplify the consequences of the original event. These responses are of part
Externí odkaz:
https://doaj.org/article/1084c5769f92475fb2371fe884253339
Autor:
R. E. J. Mitchel, Jianming Cai, Cong Liu, Mingjuan Sun, Zhiyong Chu, Fu Gao, Song Chen, Bailong Li
Publikováno v:
International Journal of Biological Sciences
It has been reported dysregulation of certain microRNAs (miRNAs / miRs) is involved in tumorigenesis. However, the miRNAs associated with radiocarcinogenesis remain undefined. In this study, we validated the upregulation of miR-467a in radiation-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750a90d9d9948ca9bd74ed8b0edb8616
https://doi.org/10.7150/ijbs.10276
https://doi.org/10.7150/ijbs.10276