Zobrazeno 1 - 10
of 28
pro vyhledávání: '"R. E. Fine"'
Publikováno v:
Journal of Neuroscience Research. 31:327-335
It is well established that iron, which is of considerable importance for normal neurological function, is highly regulated in all organ systems. However, until recently, iron regulation in the nervous system has received little attention. This study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db0c2f481b2f262274c2afac49d44f7
https://doi.org/10.1002/jnr.490310214
https://doi.org/10.1002/jnr.490310214
Publikováno v:
Neurobiology of aging. 22(3)
Processing of the beta-amyloid precursor protein (APP) in the endoplasmic reticulum and the Golgi apparatus may be critical in generating the beta-amyloid molecules linked to the pathogenesis of Alzheimer's disease. Since chaperone molecules such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1a9e9b7e0e715a5ed7b9dc39c6af5c5
https://pubmed.ncbi.nlm.nih.gov/11378243
https://pubmed.ncbi.nlm.nih.gov/11378243
Publikováno v:
Journal of neuroscience research. 62(6)
In neurons, neuropeptides and other synaptic components are transported down the axon to the synapse in vesicles using molecular motors of the kinesin family. In the synapse, these neuropeptides are found in dense core vesicles (DCVs), and, following
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc5761a513c9883ee5671a2cf2238784
https://pubmed.ncbi.nlm.nih.gov/11107168
https://pubmed.ncbi.nlm.nih.gov/11107168
Publikováno v:
Journal of neuroscience research. 60(6)
The amyloid beta peptide (A beta) is the major component of the neuritic and cerebrovascular amyloid plaques that are one of the characteristic features of Alzheimer's disease (AD). This peptide has been shown to be toxic to several relevant cell typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b8045f42da50693ea12ddc9f1c10921
https://pubmed.ncbi.nlm.nih.gov/10861793
https://pubmed.ncbi.nlm.nih.gov/10861793
Autor:
Robin J. Johnson, Barbara M. Schreiber, J S Liang, R E Fine, Ann C. McKee, Tzu-Feng Chung, Jean D. Sipe
Publikováno v:
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 7(2)
Immunohistochemical localization of the injury specific apolipoprotein, acute phase serum amyloid A (A-apoSAA), was compared in brains of patients with neuropathologically confirmed Alzheimer's disease (AD), multiple sclerosis (MS), Parkinson's disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33796f43ae554baa7528f735561a4b89
https://pubmed.ncbi.nlm.nih.gov/10842712
https://pubmed.ncbi.nlm.nih.gov/10842712
Publikováno v:
Journal of neuroscience research. 58(5)
Although calreticulin (Crt) is primarily localized to the endoplasmic reticulum (ER), our results using biotinylation and immunocytochemical methods indicate that a small but significant amount of Crt is present and forms large patches on the surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6c8a0f94300c51509400485a64f9c0d
https://pubmed.ncbi.nlm.nih.gov/10561693
https://pubmed.ncbi.nlm.nih.gov/10561693
Autor:
R E, Fine
Publikováno v:
Alzheimer disease and associated disorders. 13
Biochemical and genetic investigations have identified four key proteins, mutations in which either cause Alzheimer disease (AD) (beta-amyloid precursor protein, presenilin 1 and 2) or confer a higher risk of developing AD (apolipoprotein E). This pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13a014920e54849570394d8fd7e50108
https://pubmed.ncbi.nlm.nih.gov/10369525
https://pubmed.ncbi.nlm.nih.gov/10369525
Publikováno v:
Neuroscience letters. 217(2-3)
Gangliosides, especially GM1, attenuate the in vivo damage caused by various neurotoxins. The chemically neutral inner ester of GM1 may be a better cytoprotective agent against some neurotoxins than the parent GM1 compound, because it may cross the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0cc82af12b37f930e328d9cf0ba68c76
https://pubmed.ncbi.nlm.nih.gov/8916087
https://pubmed.ncbi.nlm.nih.gov/8916087
Publikováno v:
Biochemical and biophysical research communications. 219(3)
Since the amyloid A (AA) precursoir, serum amyloid A (apoSAA), has been shown to bind cholesterol (C) in the AA fibril forming region, we investigated the interaction of the beta-amyloid precursor protein (AbetaPP) and beta-amyloid (Abeta) peptide wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b161fa3bc92753d283898f9a0dc9c65
https://pubmed.ncbi.nlm.nih.gov/8645287
https://pubmed.ncbi.nlm.nih.gov/8645287
Publikováno v:
The American surgeon. 62(2)
The continuing increase of women participating in mammographic screening has resulted in a rise in the number of nonpalpable abnormalities identified. The development of minimally invasive and cost-effective methods to achieve accurate histologic dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f645379aac2abba05fdbf59a55aa12f6
https://pubmed.ncbi.nlm.nih.gov/8554199
https://pubmed.ncbi.nlm.nih.gov/8554199