Zobrazeno 1 - 10
of 14
pro vyhledávání: '"R. E. Desjardins"'
Autor:
R E, Desjardins
Publikováno v:
Food and drug law journal. 52(2)
Autor:
Edward L.C. Pritchett, R E Desjardins, David G. Shand, Stephen C. Hammill, Thorir D. Bjornsson
Publikováno v:
Clinical Pharmacology and Therapeutics. 29:542-547
Simulation of complex dosage regimens for drugs with multicompartmental kinetics is described using the method of separate exponentials. This approach requires that α- and β-phases are treated separately throughout and summed only at the end of the
Publikováno v:
Antimicrobial Agents and Chemotherapy. 18:317-322
Twenty-seven 2-acetylpyridine thiosemicarbazones and analogs were tested for antitrypanosomal activity against Trypanosoma rhodesiense using a semiautomated in vitro assay system. Activity was determined by relative inhibition of uptake of two radiol
Autor:
Ellen F. Boudreau, Doberstyn Eb, R. E. Desjardins, Pamplin Cl, Craig J. Canfield, Thomas M. Cosgriff
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 31:1075-1079
Abstract. Halofantrine (WR 171,669) was administered to 27 nonimmune subjects infected with the multi-drug resistant Vietnam Smith strain of Plasmodium falciparum. It was also administered to three other subjects, one infected with the Cambodian Buch
Publikováno v:
Clinical Chemistry. 30:1552-1554
We evaluated the clinical effectiveness of measuring creatine kinase (CK; EC 2.7.3.2) isoenzyme MB and lactate dehydrogenase (LD; EC 1.1.1.27) isoenzymes in diagnosis of acute myocardial infarction. We used an agarose electrophoresis method to measur
Autor:
CJ Canfield, R. L. Williams, PE Carson, R. E. Desjardins, H Frischer, KH Rieckmann, CM Trenholme
Publikováno v:
Science. 190:792-794
Mefloquine hydrochloride, a new 4-quinolinemethanol, was administered as a single oral dose to 47 volunteers infected with malaria. Treatment resulted in rapid clearence of fever and parasitemia. No recrudescence of parasites was observed after treat
Publikováno v:
Nature. 263:767-769
MALARIA is a major cause of morbidity and mortality, claiming an estimated one million lives a year in Africa alone1. Plasmodium falciparum, the most important agent of human malaria, has not been maintained for more than 2–6 d in vitro2–10. The
Autor:
Paul R. E. Desjardins, Michael Leroux
Publikováno v:
Laboratory Medicine. 20:97-99
A ward-level glucose meter program was established and maintained in our Health Sciences Centre, a l,100 bed teaching hospital serving both adults and newborns. To achieve clinically acceptable results, it was necessary to introduce a nurse “certif
Autor:
W K, Cheung, D L, Woodward, K, Shin, M, Hibberd, S, Pearse, R E, Desjardins, A, Yacobi, B M, Silber
Publikováno v:
International journal of clinical pharmacology research. 8(5)
Forty healthy male Caucasian volunteers were randomly assigned to five treatment groups to receive a placebo or a 4, 8, 12, 16 or 20 mg dose of nilvadipine. The drug was well tolerated by the subjects at all dose levels. Pharmacokinetic parameters fo
Publikováno v:
Clinical pharmacology and therapeutics. 26(3)