Zobrazeno 1 - 10
of 31
pro vyhledávání: '"R. E. Carson"'
Autor:
R. C. Eastman, R. E. Carson, K. A. Jacobson, Y. Shai, M. A. Channing, B. B. Dunn, J. D. Bacher, E. Baas, E. Jones, K. L. Kirk, al. et
Publikováno v:
Diabetes. 41:855-860
Autor:
C, Riddell, R E, Carson, J A, Carrasquillo, S K, Libutti, D N, Danforth, M, Whatley, S L, Bacharach
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(9)
Tumor detection depends on the contrast between tumor activity and background activity and on the image noise in these 2 regions. The lower the image noise, the easier the tumor detection. Tumor activity contrast is determined by physiology. Noise, h
Autor:
H, Watabe, M A, Channing, C, Riddell, F, Jousse, S K, Libutti, J A, Carrasquillo, S L, Bacharach, R E, Carson
Publikováno v:
IEEE transactions on medical imaging. 20(3)
Quantitative measurement of tumor blood flow with [15O]water can be used to evaluate the effects of tumor treatment over time. Since quantitative flow measurements require an input function, we developed the profile fitting method (PFM) to measure th
Autor:
M A, Kling, R E, Carson, L, Borg, A, Zametkin, J A, Matochik, J, Schluger, P, Herscovitch, K C, Rice, A, Ho, W C, Eckelman, M J, Kreek
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 295(3)
Stabilized methadone-maintained former heroin addicts (MTPs) treated with effective doses of methadone have markedly reduced drug craving; reduction or elimination of heroin use; normalized stress-responsive hypothalamic-pituitary-adrenal, reproducti
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 41(11)
PET was used to measure tumor blood flow, which is potentially valuable for diagnosis and assessing the effects of therapy. To help visualize regional differences in blood flow and to improve the accuracy of region-of-interest placement, a parametric
Publikováno v:
IEEE transactions on medical imaging. 19(8)
Rat brain images acquired with a small animal positron emission tomography (PET) camera and reconstructed with the three-dimensional (3-D) ordered-subsets expectation-maximization (OSEM) algorithm with resolution recovery have better quality when the
Publikováno v:
Synapse (New York, N.Y.). 38(2)
Opiate receptor avidity (B(')(max)/K(D)), was measured in the subcortex of nine females (five healthy subjects, four Alzheimer patients) and 15 males (seven healthy subjects, eight Alzheimer patients), 51-75 years of age, with the opiate receptor ant
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 41(3)
PET studies with [11C]raclopride provide an indirect measure of changes in synaptic dopamine. Previously, we used the bolus-plus-infusion (B/I) method to assess dopamine response from the percentage change in binding potential (deltaBP) before and af
Publikováno v:
Synapse (New York, N.Y.). 31(1)
Based on encouraging in vitro data indicating M2 subtype selectivity, we synthesized, radiolabeled with 18F, and evaluated 3-(3-(2-fluoroethylthio)-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetr ahydro-1-methylpyridine [FE-TZTP], and 3-(3-(3-fluoropropylthio)-1
Autor:
D O, Kiesewetter, R E, Carson, E M, Jagoda, C J, Endres, M G, Der, P, Herscovitch, W C, Eckelman
Publikováno v:
Bioorganicmedicinal chemistry. 5(8)
We have developed a multistep radiochemical synthesis of two diastereomers of quinuclidinyl-4-[18F]-fluoromethyl-benzilate ([18F]-FMeQNB), a high-affinity ligand for muscarinic acetylcholine receptors. Previously, we have shown that the nonradioactiv