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pro vyhledávání: '"R. E. Basford"'
Autor:
R. E. Basford, Harold T. Kyriazi
Publikováno v:
Journal of Neurochemistry. 47:512-528
Synaptosomes prepared and incubated in a variety of ways from rat cerebra exhibited intractable, unphysiologically low adenylate energy charge values (approximately 0.37-0.60), low total adenine nucleotide contents (approximately 8-10 nmol/mg protein
Publikováno v:
Journal of biomedical materials research. 30(1)
Biomaterial-associated infection results in increased morbidity and mortality, and may occur because of nonproductive premature activation of neutrophils resulting in impaired phagocyte function at the biomaterial surface in the event of bacterial ch
Publikováno v:
The Journal of laboratory and clinical medicine. 120(6)
The effects of the low neutral endopeptidase (24.11/CD10) exhibited by cord blood neutrophils on response to the peptide mediator of cell function f-met-leu-phe (fMLP) were investigated. Oxidative radical release (superoxide and hydrogen peroxide) an
Publikováno v:
Journal of leukocyte biology. 49(1)
Platelets are currently thought to play a role in tissue injury and inflammatory states both directly and indirectly through their action on neutrophils (PMNs). Both stimulation and inhibition of PMN superoxide anion (O2-) production by platelets has
Autor:
S S, Kaplan, R E, Basford, R L, Kormos, R L, Hardesty, R L, Simmons, E M, Mora, M, Cardona, B L, Griffith
Publikováno v:
ASAIO transactions. 36(3)
The effect of biomaterials on neutrophil function was studied in vitro to determine if these materials activated neutrophils and to determine the subsequent response of these neutrophils to further stimulation. Two biomaterials--polyurethane, a commo
Publikováno v:
Blood. 52:719-725
Chediak-Higashi (CH) syndrome, a genetic disease affecting man and other animals, is partially characterized by defective platelets that lack serotonin and dense bodies and by impaired leukocyte function where chemotaxis, degranulation, and bacterial
Autor:
S S, Kaplan, R E, Basford
Publikováno v:
Blood. 47:801-805
Morphological and quantitative neutrophil abnormalities are common in the megaloblastic anemias of vitamin B12 and folic acid deficiency. Little is known, however, about the role of these vitamins in normal leukocyte function. Seven patients with meg
Autor:
Molly T. Vogt, R. E. Basford
Publikováno v:
Journal of Neurochemistry. 15:1313-1320
— Unconjugated bilirubin caused uncoupling of oxidative phosphorylation in brain mitochondria prepared from mature or weanling rats. Human serum albumin in an amount sufficient to bind 100 per cent of the added bilirubin was able to protect the mit
Autor:
Diana S. Beattie, R. E. Basford
Publikováno v:
Journal of Biological Chemistry. 241:1419-1423
Fatty acid oxidation was studied in the presence or absence of adenosine triphosphate with the use of sodium octanoate-1-14C as substrate. In the absence of ATP, fatty acid oxidation proceeded at a rate 5 to 30% of that obtained in the presence of op
Publikováno v:
Biochemistry. 5:926-930