Zobrazeno 1 - 10
of 84
pro vyhledávání: '"R. Dornburg"'
Autor:
A Jiang, R Dornburg
Publikováno v:
Gene Therapy. 6:1982-1987
Cell type-specific gene delivery will be essential for in vivo gene therapy. Our laboratory has previously developed retroviral vector particles, derived from spleen necrosis virus, SNV, which display the antigen-binding site of an antibody on the vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24537a6e647c1d675e50ec866bfbce1
https://doi.org/10.1038/sj.gt.3301043
https://doi.org/10.1038/sj.gt.3301043
Autor:
R Dornburg, P Olson
Publikováno v:
Gene Therapy. 6:1819-1825
We have developed a genetic trap for identifying sequences that promote homologous DNA recombination. The trap employs a retroviral vector that normally disables itself after one round of replication. Insertion of defined DNA sequences into the vecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a5732a4cc30dcfe6f021d8b5425b07
https://doi.org/10.1038/sj.gt.3301035
https://doi.org/10.1038/sj.gt.3301035
Publikováno v:
Journal of Virology. 68:7060-7066
Self-inactivating (SIN) retroviral vectors contain a deletion spanning most of the right long terminal repeat's (LTR's) U3 region. Reverse transcription copies this deletion to both LTRs. As a result, there is no transcription from the 5' LTR, preven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7698e78b6bbfc4b1e2c42c034df803aa
https://doi.org/10.1128/jvi.68.11.7060-7066.1994
https://doi.org/10.1128/jvi.68.11.7060-7066.1994
Publikováno v:
Journal of Virology. 66:1336-1343
Recently, we described a retrovirus vector system with which to study formation of cDNA genes (R. Dornburg and H. M. Temin, Mol. Cell. Biol. 6:2328-2334, 1988; Mol. Cell. Biol. 8:64-72, 1990; J. Virol. 64:886-889, 1990). For these studies, retrovirus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23fdf2ad04c0eedc5a9828842c109c5
https://doi.org/10.1128/jvi.66.3.1336-1343.1992
https://doi.org/10.1128/jvi.66.3.1336-1343.1992
Autor:
Howard M. Temin, R Dornburg
Publikováno v:
Journal of Virology. 64:886-889
We showed previously that retrovirus vector particles can encapsidate RNAs without retroviral cis-acting sequences, that such RNAs are reverse transcribed in infected target cells, and that the cDNA copies are inserted into the host genome resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816691118cbf2c2827bb3bce587e2b34
https://doi.org/10.1128/jvi.64.2.886-889.1990
https://doi.org/10.1128/jvi.64.2.886-889.1990
Autor:
R, Dornburg, R J, Pomerantz
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4378c8cff11f6960ac3a9d31412d53fd
https://pubmed.ncbi.nlm.nih.gov/11013766
https://pubmed.ncbi.nlm.nih.gov/11013766
Autor:
R, Dornburg
Publikováno v:
Biological chemistry. 378(6)
The discovery that retroviruses share many features with retrotransposons led to the proposal that retroviruses evolved from cellular movable elements and became independent genetic entities, which started a parasitic life on their own. It has been f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ecf95f13af85e3a48732e5757012380
https://pubmed.ncbi.nlm.nih.gov/9224924
https://pubmed.ncbi.nlm.nih.gov/9224924
Autor:
T.-H. Tearina Chu, R. Dornburg
Publikováno v:
Journal of virology. 71(1)
Recently, we constructed retroviral vector particles derived from spleen necrosis virus (SNV) that display a single-chain antibody (scA) on the viral surface. By transient transfection protocols, we showed that such particles are competent for infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2148695d3225539928257d78b0dfc934
https://pubmed.ncbi.nlm.nih.gov/8985404
https://pubmed.ncbi.nlm.nih.gov/8985404
Autor:
R Dornburg, I Martinez
Spleen necrosis virus (SNV) is an amphotropic type C retrovirus originally isolated from a duck. The envelope protein is related to that of type D retroviruses, and SNV appears to use the same receptor as do simian retroviruses. However, little is kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1b1777001e0b698e65fd8970064590
https://europepmc.org/articles/PMC190624/
https://europepmc.org/articles/PMC190624/
Autor:
R, Dornburg
Publikováno v:
Gene therapy. 2(5)
In most human gene therapy trials, the tools of gene delivery are retroviral vectors. All current vectors are derived from murine leukemia virus (MLV). Although this system is suitable for delivering a large variety of genes into different tissues, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9a90c22c79339c434d5281ff72d7350
https://pubmed.ncbi.nlm.nih.gov/7671105
https://pubmed.ncbi.nlm.nih.gov/7671105