Zobrazeno 1 - 10
of 42
pro vyhledávání: '"R. Didsbury"'
Publikováno v:
AECL Nuclear Review. 2:109-112
The thermal neutron activation of deuterium inside a heavy-water-moderated or -cooled nuclear reactor produces a build-up of tritium in the heavy water. The in situ decay of tritium can, for certain reactor types and operating conditions, produce pot
Publikováno v:
The Journal of Immunology. 153:3267-3275
The formylpeptide (fMLP) and C5a chemoattractants were previously shown to cross-desensitize each other's ability to mobilize Ca2+ in leukocytes but not to affect nonchemoattractant Ca(2+)-mobilizing receptors, and vice versa. Our data show that all
Publikováno v:
Journal of Biological Chemistry. 268:24247-24254
To define the regulation of chemoattractant receptors, epitope-tagged human formyl peptide and C5a receptor cDNAs (ET-FR and ET-C5aR) were stably expressed in rat basophilic leukemia, RBL-2H3 cells. An antibody (12CA5) specific to "ET" was used to im
Publikováno v:
18th International Conference on Nuclear Engineering: Volume 6.
We provide an update on recent advances in pressure tube reactor (PTR) technology as exemplified by progress in the continuous research and development path that has been defined. This includes numerous and fruitful strategic development partnerships
Autor:
J van Damme, Klaus Aktories, J Vandekerckhove, Ingo Just, L Menard, J R Didsbury, C. Mohr, G Schallehn
Publikováno v:
Journal of Biological Chemistry. 267:10274-10280
We purified a novel ADP-ribosyltransferase produced by a Clostridium limosum strain isolated from a lung abscess and compared the exoenzyme with Clostridium botulinum ADP-ribosyltransferase C3. The C. limosum exoenzyme has a molecular weight of about
Publikováno v:
AECL Nuclear Review. 2:1-2
Autor:
Eric D. Tomhave, Jolin R. Didsbury, Craig Gerard, Norma P. Gerard, Ronald J. Uhing, Ralph Snyderman
Publikováno v:
FEBS Letters. 297:275-279
Human kidney 293 TSA cells were transfected by a calcium phosphate method with human formylpeptide and C5a receptor cDNAs with high efficiency. Formylpeptide receptor positive transfectants expressed a total of 968,000 +/- 34,000 receptors per cell w
Autor:
Norma P. Gerard, Ralph Snyderman, John R. Didsbury, Ronald J. Uhing, Eric D. Tomhave, Craig Gerard
Publikováno v:
Proceedings of the National Academy of Sciences. 88:11564-11568
To better define their regulation, formylpeptide and C5a chemoattractant receptor cDNAs were transiently expressed with high efficiency (approximately 35-54%) in human kidney cells. As in neutrophils, both receptors were active in elevating intracell
Publikováno v:
AECL Nuclear Review. 1:1-2
Autor:
Dmitry V. Kovalenko, Alexei Miagkov, Albert S. Baldwin, John R. Didsbury, Chadwick E. Brown, Sergei S. Makarov, Stephen A. Stimpson, John P. Cogswell
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 95(23)
The transcription factor NF-κB is a pivotal regulator of inflammatory responses. While the activation of NF-κB in the arthritic joint has been associated with rheumatoid arthritis (RA), its significance is poorly understood. Here, we examine the ro