Zobrazeno 1 - 10
of 102
pro vyhledávání: '"R. Deziel"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:129-135
Variola major virus remains a potent weapon of bioterror. There is currently an investigational-new-drug application for cidofovir for the therapy of variola major virus infections. Stittelaar and colleagues compared the levels of effectiveness of po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce87637fd70128b3b49d45bfe9013081
https://doi.org/10.1128/aac.00708-08
https://doi.org/10.1128/aac.00708-08
Autor:
E. Fine, T. Cahill, Elise Kayson, M. W. Jacobson, S. Kathuria, S. Leit, J. Smith, C. Tang, J. H. Cha, C. Higginson, Melinda M. Swenson, A. J. Lechich, L. Wasserman, H. Patzke, A. Clarke, S. Gevorkian, Noelle E. Carlozzi, Steven M. Hersch, Peter Como, C. Beck, A.E. Kane, S. Sandler, Robert Pacifici, M. C. Chirieac, T. Gillis, Thomas D. Bird, S. Peng, E. A. de Blieck, S. A. Johnson, A. Tomusk, H. D. Rosas, E. Kayson, R. Chesworth, Dennis J. Zgaljardic, J. Lee, S. Hastings, Danielle A. Simmons, David Eidelberg, Hans J. Johnson, V. Magnotta, Bernhard Landwehrmeyer, J. Wang, Elizabeth Aylward, J. L. Goldstein, Vicki L. Wheelock, N. Ramza, J. L. Marsh, S. Montas, Nonna Stepanov, Christopher A. Ross, P. Beaulieu, Elizabeth McCusker, M. K. Ahlijanian, E. Chiu, R. Deziel, Richard H. Myers, L. Carr, B. Walker, Jess G. Fiedorowicz, G. Chadwick, C. McCallum, B. Di Toro, Shannon A. Johnson, J. Srinidhi Mysore, Sharon L. Sims, Josef Priller, F. P. Albayya, Ira Shoulson, Ronald Pierson, J. F. Gusella, Jan Bausch, Kimberly A. Quaid, L. Veatch Goodman, B. Westphal, Henry L. Paulson, L. Deuel, K. Illes, Vijay Dhawan, G. Shapiro, A. Goh, G. M. Peavy, P. Young, M. Adams, J. Latourelle, Ryan Y. Kim, Aimee Aubeeluck, K. Whitlock, Douglas R. Langbehn, J.S. Paulsen, K. M. Biglan, Hillary Lipe, Kevin Duff, William Adams, J. Klager, J. Pallos, J. Dawson, F. L. Huet, D. Johnson, S. Queller, M. Casale, C. Zuccato, G. Suter, Emily Oster, P. Kingsley, S. Lifer, E. Fossale, Mark W. Jacobson, Katharine Moser, E. R. Dorsey, F. Raeppel, D. L. McArthur, A. Pae, Joan M. Harrison, Guerry M. Peavy, A. Lownie, K. Sigvardt, E. Cattaneo, Z. Li, D. Ecker, Russell Katz, A. Duckett, Aileen Shinaman, J. Besterman, Laura Mickes, Andrew Feigin, B. L. Apostol, Jana M. Hanson, Leigh J. Beglinger, L. Michels Thompson, M. Fournel, C. Moskowitz, Mark Guttman, Teresa Tempkin, Peg Nopoulos, H. Sainte-Croix, L. Beglinger, K.B. Whitlock, David Oakes, S. J. Nolan, T. Massood, N. Carlozzi, Jody Corey-Bloom, P. Mattis, G. Rahil, O. Yastrubetskaya, Marcy E. MacDonald, D.R. Langbehn, Heather Buchanan, Jody Goldstein, S. Perlman, Julie C. Stout, R. Stewart, J. Preston, Stephanie Lessig, A. Barbier, Kevin M. Biglan, Wayne R. Matson, G. Schwartz, Yilong Ma, Jane S. Paulsen
Publikováno v:
Neurotherapeutics. 5:362-375
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad4ff0e7de53fe6fe4325be2490e29f
https://doi.org/10.1016/j.nurt.2007.10.053
https://doi.org/10.1016/j.nurt.2007.10.053
Publikováno v:
Antimicrobial Agents and Chemotherapy. 51:3988-4000
The prevalence of fluoroquinolone-resistant Streptococcus pneumoniae is slowly rising as a consequence of the increased use of fluoroquinolone antibiotics to treat community-acquired pneumonia. We tested the hypothesis that increased efflux pump (EP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095792f93709bcdf3ef56be625a4e9fe
https://doi.org/10.1128/aac.00391-07
https://doi.org/10.1128/aac.00391-07
Publikováno v:
Antimicrobial Agents and Chemotherapy. 51:744-747
We determined the relationship between garenoxacin exposure and quinolone-resistant subpopulations for three bacterial isolates in an in vitro hollow-fiber infection model. An “inverted-U” relationship was identified wherein resistant subpopulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ca4ae6b3ae4319d38d1f4d06886b9f
https://doi.org/10.1128/aac.00334-06
https://doi.org/10.1128/aac.00334-06
Autor:
Karen Bush, Jennifer Basset, Arnold Louie, Henry S. Heine, Mark Kao, Lynda L. Miller, George L. Drusano, William R. Byrne, Michael Kelly, Mark R. Deziel
Publikováno v:
Antimicrobial Agents and Chemotherapy. 49:5099-5106
Expanded options for treatments directed against pathogens that can be used for bioterrorism are urgently needed. Treatment regimens directed against such pathogens can be identified only by using data derived from in vitro and animal studies. It is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee9e0bbb42287c7cfa18aed68f892f8
https://doi.org/10.1128/aac.49.12.5099-5106.2005
https://doi.org/10.1128/aac.49.12.5099-5106.2005
Publikováno v:
The Journal of Infectious Diseases. 192:420-428
The emergence of resistance to antibiotics is a serious problem often related to suboptimal drug dosing; such suboptimal dosing results in the preferential killing of drug-susceptible microbial subpopulations, allowing amplification of drug-resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9900841cd03a478460bb5cf8def49000
https://doi.org/10.1086/430611
https://doi.org/10.1086/430611
Autor:
Mark R. Deziel, Henry S. Slayter, James B. Caulfield, Paul Norton, Peter D. Chantler, Sarkis S. Margossian, Rhea J. C. Levine
Publikováno v:
Molecular and Cellular Biochemistry. 195:1-10
A neutral protease, mekratin, active in human hearts at end stage idiopathic dilated cardiomyopathy (IDC), mediates the breakdown of cardiac myosin LC2. Myosin purified from IDC heart tissue forms unusually short synthetic thick filaments. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b152273785acc3743b2da07035028ba
https://doi.org/10.1023/a:1006940513097
https://doi.org/10.1023/a:1006940513097
Autor:
H. S. Slayter, Peter D. Chantler, P. Norton, P. K. Umeda, J. B. Caulfield, P. A. W. Anderson, H. Patel, Fan Yang, A. Malhotra, Mark R. Deziel, Walter F. Stafford, S. S. Margossian
Publikováno v:
Molecular and Cellular Biochemistry. 194:301-313
Calcium regulation in the human heart is impaired during idiopathic dilated cardiomyopathy (IDC). Here, we analyze the structural basis for impairment in the regulatory mechanism. Regulation of contractility was monitored by MgATPase and Ca2+-binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfff38eaf8a22b1dd98faa69ba4fd943
https://doi.org/10.1023/a:1006980405359
https://doi.org/10.1023/a:1006980405359
Publikováno v:
Physiology & Behavior. 59:689-697
Experimental destruction of the dorsomedial hypothalamic nuclei (DMN) in weanling rats exerts an antiaging effect by preventing microalbuminuria and kidney lesions both 1 month and 1 year after lesion production. In the present study we report furthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856d30dbacd15969e14d73b01824ce5f
https://doi.org/10.1016/0031-9384(95)02138-8
https://doi.org/10.1016/0031-9384(95)02138-8
Publikováno v:
Regulatory Peptides. 60:177-183
We have recently demonstrated that synthetic peptides corresponding to the third cytoplasmic (3i) loop (residues 533 to 555) and a region in the carboxy-terminal cytoplasmic tail (residues 645 to 653) of the rat testicular follicle-stimulating hormon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d985b662ee80c828016c108d05575b
https://doi.org/10.1016/0167-0115(95)00129-8
https://doi.org/10.1016/0167-0115(95)00129-8