Zobrazeno 1 - 10
of 283
pro vyhledávání: '"R. Demuth"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Aggregatibacter actinomycetemcomitans is a gram-negative facultative anaerobe and an opportunistic oral pathogen, strongly associated with periodontitis and other inflammatory diseases. Periodontitis is a chronic inflammation of the periodontium resu
Externí odkaz:
https://doaj.org/article/d7c13eb5f8fc4094a222d87f0d67ff78
Autor:
Mohamed Y. Mahmoud, Sonali Sapare, Keegan C. Curry, Donald R. Demuth, Jill M. Steinbach-Rankins
Publikováno v:
Frontiers in Chemistry, Vol 7 (2020)
Active agents targeting key bacterial interactions that initiate biofilm formation in the oral cavity, may alter periodontitis progression; however, to date, specifically-targeted prophylactic and treatment strategies have been limited. Previously we
Externí odkaz:
https://doaj.org/article/51915530bbd841598424c2d96bc26177
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background Porphyromonas gingivalis adherence to oral streptococci is a key point in the pathogenesis of periodontal diseases (Honda in Cell Host Microbe 10:423–425, 2011). Previous work in our groups has shown that a region of the strepto
Externí odkaz:
https://doaj.org/article/8a5a4140bd564c1195338b3443c0618d
Autor:
Donald R. Demuth, Richard Lamont
Many bacterial diseases are caused by organisms growing together as communities or biofilms. These microorganisms have the capacity to coordinately regulate specific sets of genes by sensing and communicating amongst themselves utilizing a variety of
Autor:
Hetal Desai, Mohamed Y. Mahmoud, Jinlian Tan, Farnaz Minooei, Donald R. Demuth, Jill M. Steinbach-Rankins
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 835 (2020)
Porphyromonas gingivalis adherence to Streptococcus gordonii is a crucial initial event that facilitates the colonization of P. gingivalis, a key pathogen in periodontal disease. As such, blocking these early interactions may present a potential aven
Externí odkaz:
https://doaj.org/article/66948ec9e422420bb69525a5f54af8d1
Publikováno v:
Molecular Oral Microbiology
Porphyromonas gingivalis is associated with chronic periodontitis and may initially colonize the oral cavity by adhering to streptococci. Adhesion to streptococci is driven by interaction of the minor fimbrial antigen (Mfa1) with streptococcal antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebe1e0ce6d537a7731d5d4a1d3ba196
http://europepmc.org/articles/PMC7078856
http://europepmc.org/articles/PMC7078856
Peptide and non‐peptide mimetics as potential therapeutics targeting oral bacteria and oral biofilms
Publikováno v:
Molecular Oral Microbiology
The development of the oral biofilm requires a complex series of interactions between host tissues and the colonizing bacteria as well as numerous interspecies interactions between the organisms themselves. Disruption of normal host–microbe homoeos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467454cc25af3127e493199c9d59a45d
https://doi.org/10.1111/omi.12267
https://doi.org/10.1111/omi.12267
Publikováno v:
MedChemComm. 10:268-279
Several ‘second-generation’ click inhibitors of the multi-species biofilm propagated by the adherence of the oral pathogen Porphyromonas gingivalis to Streptococcus gordonii were synthesized and evaluated. The design of the structures was based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a55de2c4ad0a9783e24aad53ccc8d36
https://doi.org/10.1039/c8md00405f
https://doi.org/10.1039/c8md00405f
Publikováno v:
Frontiers in Immunology
Aggregatibacter actinomycetemcomitans is a gram-negative facultative anaerobe and an opportunistic oral pathogen, strongly associated with periodontitis and other inflammatory diseases. Periodontitis is a chronic inflammation of the periodontium resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::296439d77f43abe329611b30f27e94a3
https://pubmed.ncbi.nlm.nih.gov/34456916
https://pubmed.ncbi.nlm.nih.gov/34456916