Výsledky vyhledávání - "R. Della Nave"

Regional Distribution and Clinical Correlates of White Matter Structural Damage in Huntington Disease: A Tract-Based Spatial Statistics Study

Autor: Silvia Piacentini, R. Della Nave, Carlo Tessa, Mario Mascalchi, Andrea Ginestroni, Marco Giannelli, Massimo Filippi

Publikováno v: AJNR Am J Neuroradiol

BACKGROUND AND PURPOSE: HD entails damage of the WM. Our aim was to explore in vivo the regional volume and microstructure of the brain WM in HD and to correlate such findings with clinical status of the patients. MATERIALS AND METHODS: Fifteen HD ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e62eaf1d0680582890aac47622ffd9b
https://doi.org/10.3174/ajnr.a2128

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A Whole-Brain Analysis in De Novo Parkinson Disease

Autor: Andrea Ginestroni, Mario Mascalchi, Claudio Lucetti, R. Della Nave, Marco Giannelli, Carlo Tessa, Caterina Berti, Ubaldo Bonuccelli

Publikováno v: AJNR Am J Neuroradiol

BACKGROUND AND PURPOSE: Widespread cerebral changes are observed in advanced stages of Parkinson disease (PD), suggesting that PD is a multisystem disorder. We investigated with MR imaging whether global brain changes are present in early clinical st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f48f8b750f71d2b98cf78b38e15729
https://doi.org/10.3174/ajnr.a0900

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Whole-Brain Histogram and Voxel-Based Analyses of Diffusion Tensor Imaging in Patients with Leukoaraiosis: Correlation with Motor and Cognitive Impairment

Autor: Andrea Ginestroni, R. Della Nave, Stefano Diciotti, A Pratesi, Domenico Inzitari, Mario Mascalchi, S Foresti, Marco Inzitari, Marco Giannelli, Emilia Salvadori

Publikováno v: AJNR Am J Neuroradiol

BACKGROUND AND PURPOSE: Cerebral white matter changes, termed leukoaraiosis (LA), appearing as areas of increased signal intensity in T2-weighted MR images, are common in elderly subjects, but the possible correlation of LA with cognitive or motor de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12aea145fdc41c559e875717726ea713
https://doi.org/10.3174/ajnr.a0555

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Progression of Microstructural Damage in Spinocerebellar Ataxia Type 2: A Longitudinal DTI Study

Autor: Stefano Diciotti, Emanuele Nicolai, Andrea Bianchi, Nicola Toschi, Elena Salvatore, Carlo Tessa, R. Della Nave, Andrea Soricelli, Marco Giannelli, Mario Mascalchi, Marco Aiello, A. Ginestroni

Publikováno v: AJNR Am J Neuroradiol

BACKGROUND AND PURPOSE: The ability of DTI to track the progression of microstructural damage in patients with inherited ataxias has not been explored so far. We performed a longitudinal DTI study in patients with spinocerebellar ataxia type 2. MATER

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0ffa3ac1a787ca8be8782dd79937fa
https://europepmc.org/articles/PMC8013027/

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Brainstem neurodegeneration correlates with clinical dysfunction in SCA1 but not in SCA2. A quantitative volumetric, diffusion and proton spectroscopy MR study

Autor: Gabriele Siciliano, Giacomo Belli, Mario Mascalchi, D. De Grandis, R. Della Nave, Alessandro Filla, Andrea Ginestroni, R. Plasmati, S Foresti, Silvia Piacentini, Francesco Lolli, Laura Guerrini, Fabrizio Salvi, Carlo Tessa, Mirco Cosottini

Publikováno v: Brain. 127:1785-1795

Magnetic resonance (MR) techniques enable in vivo measurement of the atrophy of the brainstem and cerebellum in spinocerebellar ataxia type 1 (SCA1) and 2 (SCA2) patients, which is accompanied by a decrease in the concentration of N-acetyl aspartate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc2247f46e053ada3273032dd0f00ab
https://doi.org/10.1093/brain/awh201

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MRI and SPECT of midbrain and striatal degeneration in fragile X-associated tremor/ataxia syndrome

Autor: Giovanni Rizzo, Alessandra Vella, Paolo Martinelli, N. De Stefano, Mario Mascalchi, M. T. Dotti, Cesa Scaglione, Silvia Piacentini, Andrea Ginestroni, R. Della Nave, M. T. R. De Cristofaro

Publikováno v: Journal of Neurology. 255:144-146

Sirs: Fragile X-associated tremor/ataxia syndrome (FXTAS) is an inclusion disorder with an estimated prevalence among men > 50 years of age up to 1 in 3000 in the general population [16]. The neurologic phenotype of FXTAS is variable and includes int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b918843138f72837de0df8e716685633
https://doi.org/10.1007/s00415-007-0711-8

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Magnetization Transfer MR Imaging Demonstrates Degeneration of the Subcortical and Cortical Gray Matter in Huntington Disease

Autor: N. De Stefano, Lorenzo Nicola Mazzoni, R. Della Nave, Andrea Ginestroni, Silvia Piacentini, Stefano Diciotti, Marco Giannelli, Mario Mascalchi, M. Battaglini, Carlo Tessa

Publikováno v: AJNR Am J Neuroradiol

BACKGROUND AND PURPOSE: GM is typically affected in HD since the presymptomatic stage. Our aim was to investigate with MT MR imaging the microstructural changes of the residual brain subcortical and cortical GM in carriers of the HD gene and to preli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6d5d770aaf94baa97721ccdca850f2
http://hdl.handle.net/11365/23869

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Early structural changes in individuals at risk of familial Alzheimer's disease: a volumetry and magnetization transfer MR imaging study

Autor: N. De Stefano, Marco Battaglini, Marco Giannelli, Laura Bracco, Mario Mascalchi, Andrea Ginestroni, Sandro Sorbi, R. Della Nave, Valentina Bessi, Paolo Caffarra, Carlo Tessa, Benedetta Nacmias, M. Moretti

Publikováno v: Journal of neurology. 256(6)

Presenilin 1 (PS1) mutation carriers provide the opportunity to asses early features of neurodegeneration in familial Alzheimer’s disease (AD). Gray matter (GM) regional volume loss and decrease of magnetization transfer ratio (MTR) consistent with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d362679865c14e3dc62903bf0921f82
https://pubmed.ncbi.nlm.nih.gov/19252791

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Brain structural damage in spinocerebellar ataxia type 1 : a VBM study

Autor: Mario Mascalchi, Marco Giannelli, R. Plasmati, D. De Grandis, R. Della Nave, Silvia Piacentini, Fabrizio Salvi, Andrea Ginestroni, Carlo Tessa

Publikováno v: Journal of neurology. 255(8)

Neuropathological description of the brain in spinocerebellar ataxia type 1(SCA1) is limited to a few cases. Voxel-based morphometry (VBM) enables an unbiased in vivo whole-brain quantitative analysis of regional differences in gray matter (GM) and w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1527230785768039d78150015b901457
https://pubmed.ncbi.nlm.nih.gov/18438695

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Morphometry and 1H-MR spectroscopy of the brain stem and cerebellum in three patients with fragile X-associated tremor/ataxia syndrome

Autor: A, Ginestroni, L, Guerrini, R, Della Nave, C, Tessa, E, Cellini, M T, Dotti, P, Brunori, N, De Stefano, S, Piacentini, M, Mascalchi

Publikováno v: AJNR Am J Neuroradiol

SUMMARY: Morphometry and spectroscopy were performed in 3 patients with fragile X-associated tremor/ataxia syndrome (FXTAS). The brain stem and cerebellum were atrophic and satisfied criteria for olivopontocerebellar atrophy in 2 patients. However, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e13730c20400f839c672e8fe634f71ab
https://pubmed.ncbi.nlm.nih.gov/17353317

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