Výsledky vyhledávání

Akademický článek

Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance in an isogenic bacterial population

Autor: Ott Scheler, Karol Makuch, Pawel R. Debski, Michal Horka, Artur Ruszczak, Natalia Pacocha, Krzysztof Sozański, Olli-Pekka Smolander, Witold Postek, Piotr Garstecki

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)

Abstract Since antibiotic resistance is a major threat to global health, recent observations that the traditional test of minimum inhibitory concentration (MIC) is not informative enough to guide effective antibiotic treatment are alarming. Bacterial

Externí odkaz: https://doaj.org/article/a45a8ccd572d4e26bbdb9fa4a29deaec

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Generation of Nanoliter Droplets on Demand at Hundred-Hz Frequencies

Autor: Slawomir Jakiela, Pawel R. Debski, Bogdan Dabrowski, Piotr Garstecki

Publikováno v: Micromachines, Vol 5, Iss 4, Pp 1002-1011 (2014)

We describe a precision micropump for generation of precisely metered micro-aliquots of liquid at high rates. The use of custom designed piezoelectric valves positioned externally to the microfluidic chip allows for on-demand formation of micro-dropl

Externí odkaz: https://doaj.org/article/e9ade9d54eed44df8f8f574d3eecf343

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance in an isogenic bacterial population

Autor: Natalia Pacocha, Piotr Garstecki, Pawel R. Debski, Karol Makuch, Olli-Pekka Smolander, Artur Ruszczak, Ott Scheler, Witold Postek, Michał Horka, Krzysztof Sozanski

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports

Since antibiotic resistance is a major threat to global health, recent observations that the traditional test of minimum inhibitory concentration (MIC) is not informative enough to guide effective antibiotic treatment are alarming. Bacterial heterore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e88b28d554f4d6f6e9e4413ae6e708c
https://doaj.org/article/a45a8ccd572d4e26bbdb9fa4a29deaec

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Continuous Recirculation of Microdroplets in a Closed Loop Tailored for Screening of Bacteria Cultures

Autor: Pawel R. Debski, Karolina Sklodowska, Jacek A. Michalski, Piotr M. Korczyk, Miroslaw Dolata, Slawomir Jakiela

Publikováno v: Micromachines, Vol 9, Iss 9, p 469 (2018)

Emerging microfluidic technology has introduced new precision controls over reaction conditions. Owing to the small amount of reagents, microfluidics significantly lowers the cost of carrying a single reaction. Moreover, in two-phase systems, each pa

Externí odkaz: https://doaj.org/article/c8e6e098827f42bc81ae12c5f734a87c

Zobrazit plný text záznamu

Akademický článek

Simultaneous Measurement of Viscosity and Optical Density of Bacterial Growth and Death in a Microdroplet

Autor: Karolina Sklodowska, Pawel R. Debski, Jacek A. Michalski, Piotr M. Korczyk, Miroslaw Dolata, Miroslaw Zajac, Slawomir Jakiela

Publikováno v: Micromachines, Vol 9, Iss 5, p 251 (2018)

Herein, we describe a novel method for the assessment of droplet viscosity moving inside microfluidic channels. The method allows for the monitoring of the rate of the continuous growth of bacterial culture. It is based on the analysis of the hydrody

Externí odkaz: https://doaj.org/article/919962361a034c3db7ec34e0fec951d4

Zobrazit plný text záznamu