Zobrazeno 1 - 10
of 10
pro vyhledávání: '"R. Dean Hautamaki"'
Autor:
Steven D. Shapiro, Lynn A. Cornelius, Jay L. Grisolano, A. McGarry Houghton, R. Dean Hautamaki, Leslie C. Nehring, Dale K. Kobayashi, Mary Baumann
Publikováno v:
Cancer Research. 66:6149-6155
Matrix metalloproteinases (MMP) have been implicated in virtually all aspects of tumor progression. However, the recent failure of clinical trials employing synthetic MMP inhibitors in cancer chemotherapy has led us to hypothesize that some MMPs may
Autor:
Rabih M. Salloum, William M. Mendenhall, David J. Dolson, Saeed R. Khan, V. Suzanne Klimberg, Donald A. Plumley, Edward M. Copelandiii, Kirby I. Bland, Raymond L. Hackett, Wiley W. Souba, Frank J. Bova, R. Dean Hautamaki
Publikováno v:
Cancer. 66:62-68
Glutamine may be an essential dietary component, especially for the support of intestinal mucosal growth and function. This study evaluated the effects of a glutamine-enriched elemental diet, administered before whole-abdominal radiation on gut gluta
Autor:
V. Suzanne Klimberg, Wiley W. Souba, William H. Mendenhall, R. Dean Hautamaki, Edward M. Copeland, Frank C. Bova, Kirby I. Bland, Richard J. Howard
Publikováno v:
Journal of Surgical Research. 48:1-5
The effect of dietary glutamine on bacterial translocation was studied in rats following administration of a single dose of abdominal radiation (1000 rad) that causes a reproducible mucosal injury and results in a high incidence of culture-positive m
Autor:
Daniel T. Holley, Edward M. Copeland, V. Suzanne Klimberg, Wiley W. Souba, David J. Dolson, Rabih M. Salloum, R. Dean Hautamaki
Publikováno v:
The American Journal of Surgery. 159:27-33
Gut glutamine utilization after massive small bowel resection was studied to gain further insight into the alterations and adaptations in intestinal glutamine metabolism that occur during the development of post-resectional hyperplasia. After resecti
Publikováno v:
Science (New York, N.Y.). 277(5334)
To determine which proteinases are responsible for the lung destruction characteristic of pulmonary emphysema, macrophage elastase–deficient (MME −/− ) mice were subjected to cigarette smoke. In contrast to wild-type mice, MME − / − mice di
Autor:
Kenneth Herskowitz, Tomas D. Martin, Wiley W. Souba, R. Dean Hautamaki, Edward M. Copeland, Donald A. Plumley
Publikováno v:
The Journal of surgical research. 51(1)
Despite the attenuated skeletal muscle proteolysis that occurs following hypothermic anesthesia and open heart surgery, blood amino acid levels are maintained, suggesting enhanced amino acid release by another organ. To investigate the role of the lu
Autor:
V. Suzanne Klimberg, Frank C. Bova, Donald A. Plumley, David J. Dolson, Kirby I. Bland, Rabih M. Salloum, Edward M. Copeland, Wiley W. Souba, Michael Kasper, William R. Mendenhall, R. Dean Hautamaki
Publikováno v:
Archives of surgery (Chicago, Ill. : 1960). 125(8)
• The healing effects of glutamine given orally for 8 days as a single amino acid nutrient after treatment with whole abdominal radiation (10 Gy) were studied. Rats received isonitrogenous and isovolumic diets containing 3% glutamine or 3% glycine.
Autor:
R. Dean Hautamaki, W. Robert Rout, Wiley W. Souba, Edward M. Copeland, Donald A. Plumley, Tomas D. Martin, Timothy C. Flynn
Publikováno v:
Archives of surgery (Chicago, Ill. : 1960). 125(1)
• Amino acid flux across the lungs was studied in humans to gain further insight into the altered nitrogen metabolism that characterizes catabolic disease states. Lung flux of glutamine, glutamate, and alanine was determined in three groups of surg
Publikováno v:
Brain research. 403(2)
Several presynaptic processes were studied in cerebral cortical synaptosomes prepared from intact adult female rats or from ovariectomized animals that received 3 subcutaneous injections of either estradiol benzoate (10 micrograms/kg) or vehicle. Inj
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