Zobrazeno 1 - 10
of 118
pro vyhledávání: '"R. Davis Manning"'
Publikováno v:
Journal of the American Society of Hypertension. 6:100-108
Progressive renal fibrosis is a characteristic of all the diseases that cause renal failure and is invariably accompanied by a prominent leukocyte infiltration in the kidney. The goal of this study was to determine the association between the circula
Autor:
Celso E. Gomez-Sanchez, Luis A. Juncos, Xiaolong Zhu, Deyin Lu, R. Davis Manning, Yiling Fu, Ruisheng Liu
Publikováno v:
American Journal of Physiology-Renal Physiology. 301:F529-F535
Two major factors which regulate tubuloglomerular feedback (TGF)-mediated constriction of the afferent arteriole are release of superoxide (O2−) and nitric oxide (NO) by macula densa (MD) cells. MD O2− inactivates NO; however, among the factors t
Publikováno v:
Journal of the American Society of Hypertension. 4:272-283
Although total white blood cell (WBC) count has been associated with hypertension, the association between specific WBC types and blood pressure (BP) levels has not been studied. In a cohort of 5746 middle-age African-American and white adults free o
Autor:
Luis A. Juncos, Haifeng Liu, Yiling Fu, Arnaldo Lopez-Ruiz, Ramiro Juncos, Rui Zhang, Deyin Lu, R. Davis Manning, Ruisheng Liu
Publikováno v:
American Journal of Physiology-Renal Physiology. 298:F1465-F1471
Neuronal nitric oxide synthase (nNOS), which is abundantly expressed in the macula densa cells, attenuates tubuloglomerular feedback (TGF). We hypothesize that splice variants of nNOS are expressed in the macula densa, and nNOS-beta is a salt-sensiti
Autor:
Jian-Wei Gu, Brandi Sartin, R. Davis Manning, Emily Young, Amelia Purser Bailey, Megan Shparago
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 297:R142-R148
Clinical evidence links the inhibition of VEGF to hypertension. However, the mechanisms by which VEGF affects the pathogenesis of hypertension remain in question. We determined 1) whether administration of VEGF receptor inhibitor SU5416 enhances diet
Autor:
Rebecca A. Rose, Michael D Hughson, R. Davis Manning, Sharkeshia Jordan, Niu Tian, Terry M Dwyer
Publikováno v:
Journal of Hypertension. 24:2263-2270
Salt-sensitive hypertension in humans and experimental animals causes progressive increases in renal damage and dysfunction. The Dahl salt-sensitive (S) rat closely mimics human salt-sensitive hypertension.Our goal was to test the hypothesis that enh
Publikováno v:
Hypertension. 45:934-939
The goal of this study was to test the hypothesis that oxidative stress in Dahl salt-sensitive (SS) rats on a high-sodium intake contributes to the progression of renal damage, the decreases in renal hemodynamics, and the development of hypertension.
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 284:R372-R379
The goal of this study was to determine the role of renal medullary inducible nitric oxide synthase (iNOS) in the arterial pressure, renal hemodynamic, and renal excretory changes that occur in Dahl/Rapp salt-resistant (R) and salt-sensitive (S) rats
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 283:R732-R738
The roles of oxidative stress and renal superoxide dismutase (SOD) levels and their association with renal damage were studied in Dahl salt-sensitive (S) and salt-resistant (R)/Rapp strain rats during changes in Na intake. After 3 wk of a high (8%)-N