Zobrazeno 1 - 10
of 194
pro vyhledávání: '"R. Damle"'
Autor:
Sheela R. Damle, Agata K. Krzyzanowska, Maximilian K. Korsun, Kyle W. Morse, Susannah Gilbert, Han Jo Kim, Oheneba Boachie-Adjei, Bernard A. Rawlins, Marjolein C. H. van der Meulen, Matthew B. Greenblatt, Chisa Hidaka, Matthew E. Cunningham
Publikováno v:
Cells, Vol 12, Iss 20, p 2488 (2023)
Bone morphogenetic protein (BMP) gene delivery to Lewis rat lumbar intervertebral discs (IVDs) drives bone formation anterior and external to the IVD, suggesting the IVD is inhospitable to osteogenesis. This study was designed to determine if IVD des
Externí odkaz:
https://doaj.org/article/d070ea3a8d62465ea1611f79d34193e0
Autor:
Andrea J. Luker, Laura J. Graham, Timothy M. Smith, Carmen Camarena, Matt P. Zellner, Jamie-Jean S. Gilmer, Sheela R. Damle, Daniel H. Conrad, Harry D. Bear, Rebecca K. Martin
Publikováno v:
BMC Immunology, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background Myeloid derived suppressor cells (MDSCs) present a significant obstacle to cancer immunotherapy because they dampen anti-tumor cytotoxic T cell responses. Previous groups, including our own, have reported on the myelo-depletive ef
Externí odkaz:
https://doaj.org/article/8705275c0da24e8995eee5018ccbc1c7
Autor:
Rebecca K. Martin, Sheela R. Damle, Yolander A. Valentine, Matthew P. Zellner, Briana N. James, Joseph C. Lownik, Andrea J. Luker, Elijah H. Davis, Martha M. DeMeules, Laura M. Khandjian, Fred D. Finkelman, Joseph F. Urban, Jr., Daniel H. Conrad
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1824-1834 (2018)
Summary: Helminth infection is known for generating large amounts of poly-specific IgE. Here we demonstrate that innate-like B1 cells are responsible for this IgE production during infection with the nematode parasites Nippostrongylus brasiliensis an
Externí odkaz:
https://doaj.org/article/f4577ef0704b41a9a257d4dd0468027d
Akademický článek
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Autor:
Tony Chen, Miguel Otero, Matthew E. Cunningham, Sheela R. Damle, Robert J Frawley, Agata Krzyzanowska
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Spontaneous mineralization of the nucleus pulposus (NP) has been observed in cases of intervertebral disc degeneration (IDD). Inflammatory cytokines have been implicated in mineralization of multiple tissues through their modulation of expression of
Autor:
Andrea J Luker, Laura J Graham, Matthew P Zellner, Jamie-Jean S Gilmer, Sheela R Damle, Daniel H Conrad, Rebecca K Martin, Harry D Bear
Background: Myeloid derived suppressor cells (MDSC) represent a significant hurdle to cancer immunotherapy because they dampen anti-tumor cytotoxic T cell responses. Previous groups, including our own, have reported on the myelo-depletive effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::535655981f3d0a2a6ca48d1ddc2f2a90
https://doi.org/10.21203/rs.2.15818/v1
https://doi.org/10.21203/rs.2.15818/v1
Autor:
Andrea J. Luker, Daniel H. Conrad, Jamie-Jean S. Gilmer, Harry D. Bear, Rebecca K. Martin, Matt P. Zellner, Timothy M. Smith, Laura Graham, Carmen Camarena, Sheela R. Damle
Publikováno v:
BMC Immunology
BMC Immunology, Vol 21, Iss 1, Pp 1-15 (2020)
BMC Immunology, Vol 21, Iss 1, Pp 1-15 (2020)
Background Myeloid derived suppressor cells (MDSCs) present a significant obstacle to cancer immunotherapy because they dampen anti-tumor cytotoxic T cell responses. Previous groups, including our own, have reported on the myelo-depletive effects of
Autor:
Joseph C. Lownik, Lauren Folgosa Cooley, Riham El Sayed, Andrea J. Luker, Costantino Pitzalis, Rebecca K. Martin, Mohey Eldin M. El Shikh, Andreas Hutloff, Daniel H. Conrad, Sheela R. Damle
Publikováno v:
The Journal of Immunology. 199:2305-2315
The proper regulation of ICOS and ICOS ligand (ICOSL) has been shown to be essential for maintaining proper immune homeostasis. Loss of either protein results in defective humoral immunity, and overexpression of ICOS results in aberrant Ab production
Autor:
Allen Smith, Daniel H. Conrad, Sheela R. Damle, Chelsea L. Cockburn, Joseph C. Lownik, Jason A. Carlyon, Rebecca K. Martin
Publikováno v:
Allergy. 73:125-136
Background Allergy and allergic asthma are significant health burdens in developed countries and are increasing in prevalence. Dendritic cells (DCs) initiate immune responses to common aeroallergens, and ADAM10 has been demonstrated to be important f
Autor:
Pamela DeRosse, Anil K. Malhotra, Majnu John, Nishad R Damle, Toshikazu Ikuta, Philip R. Szeszko, Bart D. Peters
Publikováno v:
Brain Structure and Function. 222:2183-2192
The interthalamic adhesion (ITA) is an understudied neuroanatomical structure that forms a bridge of tissue connecting the thalamus of each hemisphere across the midline whose functional significance remains largely unknown. The likelihood of ITA abs