Zobrazeno 1 - 10
of 1 227
pro vyhledávání: '"R. Daga"'
Autor:
Kanupriya R. Daga, Andrew M. Larey, Maria G. Morfin, Kailin Chen, Sara Bitarafan, Jana M. Carpenter, Hannah M. Hynds, Kelly M. Hines, Levi B. Wood, Ross A. Marklein
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-21 (2024)
Abstract Background Mesenchymal stromal cell derived extracellular vesicles (MSC-EVs) are a promising therapeutic for neuroinflammation. MSC-EVs can interact with microglia, the resident immune cells of the brain, to exert their immunomodulatory effe
Externí odkaz:
https://doaj.org/article/ed07ae149d72409faf0f21728dc5d06e
Autor:
Gabriel Ruiz-Romero, María Dolores Berdún, Mark Hochstrasser, Silvia Salas-Pino, Rafael R. Daga
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111095- (2024)
Summary: In addition to the degradation of cell-cycle proteins, short-lived, damaged, or unfolded proteins are constantly cleared from cells by the proteasome. During proliferation, the proteasome localizes to the nucleus and cytoplasm; however, the
Externí odkaz:
https://doaj.org/article/bb7d26f9b8074939a6a339c47b330b6a
Autor:
Andrew M. Larey, Thomas M. Spoerer, Kanupriya R. Daga, Maria G. Morfin, Hannah M. Hynds, Jana Carpenter, Kelly M. Hines, Ross A. Marklein
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 153-171 (2024)
Due to their immunomodulatory function, mesenchymal stromal cells (MSCs) are a promising therapeutic with the potential to treat neuroinflammation associated with neurodegenerative diseases. This function is mediated by secreted extracellular vesicle
Externí odkaz:
https://doaj.org/article/117fb0ce6fda42fcb4c68978057c974e
Autor:
Ana Belén Iglesias-Romero, Terersa Soto, Ignacio Flor-Parra, Silvia Salas-Pino, Gabriel Ruiz-Romero, Kathleen L. Gould, José Cansado, Rafael R. Daga
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Mitogen-activated protein kinases (MAPKs) preserve cell homeostasis by transducing physicochemical fluctuations of the environment into multiple adaptive responses. These responses involve transcriptional rewiring and the regulati
Externí odkaz:
https://doaj.org/article/be36313b2d3549719a218fbca1f39f4f
Publikováno v:
Life, Vol 13, Iss 10, p 1960 (2023)
The emergence of Darwinian evolution represents a central point in the history of life as we know it. However, it is generally assumed that the environments in which life appeared were hydrothermal environments, with highly variable conditions in ter
Externí odkaz:
https://doaj.org/article/9c7dc5ab9aa64e31994e2d021b77dc43
Autor:
Debora B. Araujo, Joana R. Dantas, Karina R. Silva, Débora L. Souto, Maria de Fátima C. Pereira, Jessica P. Moreira, Ronir R. Luiz, Cesar S. Claudio-Da-Silva, Monica A. L. Gabbay, Sergio A. Dib, Carlos E. B. Couri, Angelo Maiolino, Carmen L. K. Rebelatto, Debora R. Daga, Alexandra C. Senegaglia, Paulo R. S. Brofman, Leandra Santos Baptista, José E. P. Oliveira, Lenita Zajdenverg, Melanie Rodacki
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Objective: To evaluate the short term safety and potential therapeutic effect of allogenic adipose tissue-derived stromal/stem cells (ASCs) + cholecalciferol in patients with recent-onset T1D.Methods: Prospective, phase II, open trial, pilot study in
Externí odkaz:
https://doaj.org/article/d415c715ff804350b123ce8576df0eb6
Autor:
Ignacio Flor-Parra, Ana Belén Iglesias-Romero, Silvia Salas-Pino, Rafael Lucena, Juan Jimenez, Rafael R. Daga
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 933-941 (2018)
Summary: In metazoans, the nuclear envelope (NE) breakdown (NEBD) occurs during “open” mitosis and meiosis. In the fission yeast Schizosaccharomyces pombe, the mitosis and the first meiotic division (MI) are “closed,” during which the NE is m
Externí odkaz:
https://doaj.org/article/b4a9f3e13b734d7ba83e63206f14dc0a
Publikováno v:
Malaysian Orthopaedic Journal; Mar2024, Vol. 18 Issue 1, p73-83, 11p
Autor:
Hidalgo, Susanna Boronat, Margarita Cabrera, Montserrat Vega, Jorge Alcalá, Silvia Salas-Pino, Rafael R. Daga, José Ayté, Elena
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 11202
When misfolded intermediates accumulate during heat shock, the protein quality control system promotes cellular adaptation strategies. In Schizosaccharomyces pombe, thermo-sensitive proteins assemble upon stress into protein aggregate-like centers, P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::d6eec8b098458a018c415150091fde70
Publikováno v:
Microbial Cell, Vol 4, Iss 12, Pp 423-425 (2017)
Our view of the nuclear pore complexes (NPCs) as gateways between the nuclear and cytoplasmic compartments has been largely expanded in recent years. NPCs have now demonstrated roles in genome regulation and maintenance from single cells to multicell
Externí odkaz:
https://doaj.org/article/3f01c33b540946e28ab44b3e49aaad01