Zobrazeno 1 - 10 of 10 pro vyhledávání: '"R. D. Sitrin"'
1
Optimization and scale-up of solvent extraction in purification of hepatitis A virus (VAQTA)
Autor: A J, Hagen, C N, Oliver, R D, Sitrin
Publikováno v: Biotechnology and bioengineering. 56(1)
Solvent extraction is a very powerful purification step in the preparation of VAQTA, a highly purified, inactivated hepatitis A vaccine. Extraction of an aqueous product-containing protein solution with chloroform through vigorous shaking causes irre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::110a2dff32443fddab44ce439177c06e
https://pubmed.ncbi.nlm.nih.gov/18636612
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3
Use of nuclease enzyme in the purification of VAQTA, a hepatitis A vaccine
Autor: A J, Hagen, R A, Aboud, P A, DePhillips, C N, Oliver, C J, Orella, R D, Sitrin
Publikováno v: Biotechnology and applied biochemistry. 23(3)
The development of the purification process for VAQTA, which results in a highly purified inactivated hepatitis A vaccine, was driven by modifications in the cell-culture and harvest methods which permit hepatitis A virus propagation to support large
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c66a508d522ad3ee34959b55f055b921
https://pubmed.ncbi.nlm.nih.gov/8679106
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4
Analytical HPLC of the aridicin glycopeptide complex and its application to fermentation development
Autor: S. Vogt-Speth, Louis J. Nisbet, R. D. Sitrin, Michael J. Polansky, G. Chan, Charles H. Pan
Publikováno v: Journal of Industrial Microbiology. 1:303-310
A gradient analytical HPLC system was developed to assay titers of the three major components of the aridicin (Ardacin) complex produced byKibdelosporangium aridum (SK&F AAD-216). The separation was performed on a Beckman Ultrasphere column using a g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6dbaeb8f340cea6423ccd1a094d5f402
https://doi.org/10.1007/bf01569308
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5
Charge and lipophilicity govern the pharmacokinetics of glycopeptide antibiotics
Autor: D H Pitkin, Louis J. Nisbet, B A Mico, R D Sitrin
Publikováno v: Antimicrobial Agents and Chemotherapy. 29:440-444
The pharmacokinetics and urinary excretion of nine glycopeptide antibiotics with diverse pIs (3.8 to 8.5) and lipophilicities were studied. The disposition of the aridicin antibiotics and their hydrolysis products were examined in male CD-1 mice afte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50ce05b2c8afc6bd1a0f07b3cb3a090
https://doi.org/10.1128/aac.29.3.440
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Plný text Recenzováno Digitální knihovna AV ČR
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