Výsledky vyhledávání - "R. D. Sigmund"

Localization of epithelial sodium channel subunit mRNAs in adult rat lung by in situ hybridization

Autor: Paul B. Mccray, Michael J. Welsh, K. Matsushita, R. D. Sigmund, John B. Stokes

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 271:L332-L339

The transport of Na+ through amiloride-sensitive sodium channels (ENaC) plays a major role in the absorption of fluid across the pulmonary epithelium. The proteins forming the ENaC channel are encoded by three genes in the rat (alpha-, beta-, and gam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1903d84726c54ab6e80355237fc3ec6
https://doi.org/10.1152/ajplung.1996.271.2.l332

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Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoechst 33258, and 4',6-diamidine-2-phenylindole

Autor: J M, Woynarowski, M, McHugh, R D, Sigmund, T A, Beerman

Publikováno v: Molecular pharmacology. 35(2)

The effects of distamycin, Hoechst 33258, and 4',6-diamidine-2-phenylindole (DAPI) on the catalytic activity of topoisomerase II from L1210 cells were determined. These compounds were used as model agents capable of AT-specific binding in the minor g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3587307765a4f921262dea2a807e2c92
https://pubmed.ncbi.nlm.nih.gov/2465485

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