Zobrazeno 1 - 10
of 287
pro vyhledávání: '"R. D. Johnston"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Background and aims: Atherosclerotic plaque rupture in the carotid artery can cause small emboli to travel to cerebral arteries, causing blockages and preventing blood flow leading to stroke. Contrast enhanced micro computed tomography (CEμCT) using
Externí odkaz:
https://doaj.org/article/4d77b9009b914ed8a1cb2c89bfedf9b2
Recent developments with novel systemic drugs, palliative surgical techniques and diagnostic imaging have given hope for the treatment of patients whose breast cancer has spread beyond its primary tumour. Written by a team from leading cancer centers
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
A critical decline of functional insulin-producing pancreatic β-cells is the central pathologic element of both type 1 and type 2 diabetes. Mammalian Sterile 20-like kinase 1 (MST1) is a key mediator of β-cell failure and the identification of nera
Externí odkaz:
https://doaj.org/article/0c9dd3492760421480a43eb22fe8b545
Autor:
Stephen R. D. Johnston
Publikováno v:
Annals of Palliative Medicine. 12:421-426
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::474e18f19df74af32188f6525b7d7327
https://doi.org/10.21037/apm-22-981
https://doi.org/10.21037/apm-22-981
Autor:
Stephen R D, Johnston
Publikováno v:
Hematology/Oncology Clinics of North America. 37:89-102
There is now a deeper understanding of the biology of hormone receptor-positive (HR+) early breast cancer (EBC) that can be used to inform assessment of risk and prognosis, and also guide more effective adjuvant systemic therapies. For postmenopausal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05bd8e4378d29fc6f48e0b56673dc4ad
https://doi.org/10.1016/j.hoc.2022.08.011
https://doi.org/10.1016/j.hoc.2022.08.011
Autor:
Stephen R D, Johnston, Masakazu, Toi, Joyce, O'Shaughnessy, Priya, Rastogi, Mario, Campone, Patrick, Neven, Chiun-Sheng, Huang, Jens, Huober, Georgina Garnica, Jaliffe, Irfan, Cicin, Sara M, Tolaney, Matthew P, Goetz, Hope S, Rugo, Elzbieta, Senkus, Laura, Testa, Lucia, Del Mastro, Chikako, Shimizu, Ran, Wei, Ashwin, Shahir, Maria, Munoz, Belen, San Antonio, Valérie, André, Nadia, Harbeck, Miguel, Martin
Publikováno v:
The Lancet Oncology. 24:77-90
Adjuvant abemaciclib plus endocrine therapy previously showed a significant improvement in invasive disease-free survival and distant relapse-free survival in hormone receptor-positive, human epidermal growth factor receptor 2 (HER2; also known as ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff773b443545dc60195d174427ba206
https://doi.org/10.1016/s1470-2045(22)00694-5
https://doi.org/10.1016/s1470-2045(22)00694-5
Publikováno v:
npj Breast Cancer. 9
The human epidermal growth factor receptor 2 (HER2) is overexpressed in 13–22% of breast cancers (BC). Approximately 60–70% of HER2+ BC co-express hormone receptors (HRs). HR/HER2 co-expression modulates response to both anti-HER2–directed and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::108ec9b5aec24befaebb05603ff58bc4
https://doi.org/10.1038/s41523-023-00533-2
https://doi.org/10.1038/s41523-023-00533-2
Autor:
Basrull N. Bhaludin, Nina Tunariu, Dow-Mu Koh, Christina Messiou, Alicia F. Okines, Sophie E. McGrath, Alistair E. Ring, Marina M. Parton, Bhupinder Sharma, Tanja Gagliardi, Steven D. Allen, Romney Pope, Stephen R. D. Johnston, Kate Downey
Publikováno v:
European Radiology. 32:6514-6525
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a7da00a1116c70dd3b1a506399b7be0
https://doi.org/10.1007/s00330-022-08714-6
https://doi.org/10.1007/s00330-022-08714-6
Autor:
Lindsay L. Peterson, Mark R. Somerfield, Larissa A. Korde, Harold J. Burstein, Rachel L. Yung, Dharamvir Jain, Stephen R. D. Johnston, Jennifer K. Litton, Debra L. Barton, Lesley Fallowfield, Praveen Vikas, Erin Macrae, Ali Dorris, Hope S. Rugo
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 39, iss 35
J Clin Oncol
J Clin Oncol
PURPOSE To update recommendations of the ASCO systemic therapy for hormone receptor (HR)-positive metastatic breast cancer (MBC) guideline. METHODS An Expert Panel conducted a systematic review to identify new, potentially practice-changing data. RES
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e630d5df3b3a8bef6137fbb799786d
https://doi.org/10.1200/jco.21.01392
https://doi.org/10.1200/jco.21.01392
Autor:
Andrew Dodson, Sophie Perry, Stephen R. D. Johnston, Claire Swift, Shannon Puhalla, Judith M Bliss, Melanie Finnigan, Katherine L. Pogue-Geile, Maggie C.U. Cheang, C. Kent Osborne, Yuan Liu, Lucy Kilburn, Mitch Dowsett, Vera Martins, Samuel A. Jacobs, Mothaffar F. Rimawi, Chris Holcombe, Nicholas C. Turner
Publikováno v:
Clinical Cancer Research. 28:163-174
Purpose: To determine (i) the relationship between candidate biomarkers of the antiproliferative (Ki67) response to letrozole and palbociclib alone and combined in ER+/HER2− breast cancer; and (ii) the pharmacodynamic effect of the agents on the bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06dd1ba43723b938f516af92d5838969
https://doi.org/10.1158/1078-0432.ccr-21-1628
https://doi.org/10.1158/1078-0432.ccr-21-1628