Zobrazeno 1 - 10
of 18
pro vyhledávání: '"R. D. IRWIN"'
Autor:
R. D. Irwin, S. C. Medeiros, S. Venugopal, J. C. Malas, A. Chaudhary, W. M. Mullins, William G. Frazier, E. A. Medina
Publikováno v:
Materials Science and Technology. 14:25-31
Modern control theory has been applied to the optimisation of microstructure development during hot extrusion. This approach involves state space type models for describing the material behaviour and the mechanics of the process. The problem of deter
Autor:
Jinhua Yuan, Evelyn Murrill, Thomas J. Goehl, R. Moore, James A. Clark, H. L. Hong, R. D. Irwin
Publikováno v:
Xenobiotica. 24:553-560
1. The toxicokinetics of pentachlorophenol (PCP) were studied in the Fischer 344 rat using i.v. and oral (gavage, dosed feed) routes of exposure. 2. Only minor sex differences were observed in the elimination kinetics of PCP after i.v. administration
Publikováno v:
Toxicological Sciences. 17:159-176
Autor:
G B J Smith, Abraham Nyska, Marc R. Kok, Changyu Zheng, B J Baum, Antonis Voutetakis, Corinne M. Goldsmith, R D Irwin, Molly Vallant, Susan A. Elmore
Publikováno v:
Oral diseases, 12(2), 137-144. Wiley-Blackwell
OBJECTIVE: We examined the toxicity and biodistribution associated with a single administration of a first-generation, serotype 5, adenoviral vector encoding human growth hormone (hGH; AdCMVhGH) to a single rat submandibular gland in the presence of
Publikováno v:
Journal of applied toxicology : JAT. 19(2)
1,2-Dihydro-2,2,4-trimethylquinoline (TMQ) was evaluated in a 2-year study in which groups of 60 male or female F344 rats received 0, 36 or 60 mg kg(-1) (0, 0.022, or 0.037 mg cm(-2)) and groups of 60 male or female B6C3F1 mice received 0, 3.6 or 10
Publikováno v:
Journal of applied toxicology : JAT. 17(3)
Groups of F344 rats and B6C3F1 mice were exposed to furfuryl alcohol vapor for 6 hours per day, 5 days per week for 14 days (0, 16, 31, 63, 125, 250 ppm) or 13 weeks (0, 2, 4, 8, 16, 32 ppm). Reduced survival was observed in the 14-day study at 250 p
Publikováno v:
Journal of applied toxicology : JAT. 16(3)
Glycidol, a simple aliphatic epoxide, was administered by gavage in water to groups of male and female F344/N rats and B6C3F1 mice. Rats received 0, 37.5 or 75 mg kg-1 and mice received 0, 25 or 50 mg kg-1 daily, 5 days per week for 2 years. Exposure
NTP summary report on the metabolism, disposition, and toxicity of 1,4-butanediol (CAS No. 110-63-4)
Autor:
R D, Irwin
Publikováno v:
Toxicity report series. (54)
1,4-Butanediol is an industrial chemical used in the manufacture of other organic chemicals. It was nominated by the National Cancer Institute and selected for evaluation by the NTP because of high production volume, the potential for worker exposure
Publikováno v:
International journal of paediatric dentistry. 5(3)
Methods that have been proposed for mixed dentition analysis are reviewed. Prediction of the space required in the dental arch for unerupted permanent canines and premolars has been based either on the correlation between the mesio-distal widths of t
Autor:
James A. Clark, Lily H. Hong, Thomas J. Goehl, Jinhua Yuan, Evelyn Murrill, R. Moore, R. D. Irwin
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 23(4)
1. Toxicokinetics of pentachloroanisole (PCA) were studied in F344 rat and B6C3F1 mouse of both sexes by gavage at doses of 10, 20 and 40 mg/kg and by i.v. at 10 mg/kg. 2. PCA was rapidly demethylated to pentachlorophenol (PCP) in both rat and mouse