Zobrazeno 1 - 10
of 97
pro vyhledávání: '"R. D. Higginbotham"'
Autor:
L. T. Patterson, R. D. Higginbotham
Publikováno v:
Journal of Bacteriology. 90:1520-1524
Patterson , L. T. (University of Texas, Galveston), and R. D. Higginbotham . Mouse C-reactive protein and endotoxin-induced resistance. J. Bacteriol. 90: 1520–1524. 1965.—The relationship between the level of C-reactive protein (CRP) in the sera
Autor:
R. D. Higginbotham
Publikováno v:
Experimental Biology and Medicine. 102:4-8
Summary(1) Compound 48/80 appears to have an additive effect on toxicity of histamine and a synergistic effect on toxicity of serotonin in the mouse. (2) Heparin interferes with this compound 48/80 effect on lethal intoxication with histamine or sero
Autor:
R. D. Higginbotham, S. Karnella
Publikováno v:
The Journal of Immunology. 106:233-240
Local tissue mast cells were found to rapidly secrete their heparin-containing granules in a dose-related response to subcutaneous injection of relatively small amounts of bee venom. The shed granules formed complexes with cationic protein in vivo an
Publikováno v:
Experimental Biology and Medicine. 80:758-761
SummaryThe reduplication of Eastern equine encephalomyelitis virus in mouse brain is delayed in mice previously treated with sodium monofluoroacetate. This chemical seems to prolong the survival time of the infected animals, although it does not othe
Publikováno v:
Experimental Biology and Medicine. 92:256-261
SummaryIt has been observed that following mild trauma to the skin of mice, degranulation of mast cells occurs in the subcutaneous connective tissue and is followed by the appearance of metachromatic granules within the cytoplasm of surrounding fibro
Publikováno v:
The Journal of Immunology. 79:259-264
Summary It was observed that locally injected antigen initiates a more wide-spread degranulation of local tissue mast cells in sensitized mice than in controls. The fate of the shed mast celt granules in the tissues is described and the significance
Publikováno v:
Experimental Biology and Medicine. 92:493-498
Summary1. Mice pretreated with various amounts of heparin exhibit resistance, relative to heparin dose, to the toxic effects of subsequent injections of otherwise lethal doses of 48/80. There is a straight-line relationship between the 50% protective
Publikováno v:
Journal of Bacteriology. 95:1375-1379
The response of rabbits and mice to treatment with Escherichia coli endotoxin, as measured by C-reactive protein (CRP) and leukocyte levels, and resistance to Staphylococcus aureus infection was studied to evaluate the significance of these responses
Autor:
R. D. Higginbotham
Publikováno v:
The Journal of Immunology. 95:867-875
Summary It was observed that the subcutaneous injection of Russell's Viper venom initiated an explosive release of heparin-containing granules from local tissue mast cells and that the shed granules were subsequently ingested by fibroblasts and vario
Autor:
J.M. Clark, R. D. Higginbotham
Publikováno v:
Toxicon. 8:25-32
Studies have shown that resistance to the lethal effects of intravenous challenge of mice with moccasin (Agkistrodon p. piscivorous) venom is impaired by either adrenalectomy or vaccination and that this deficiency is exaggerated in adrenalectomized-