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Cefuroxime - A new cephalosporin antibiotic

Autor: R. B. Sykes, D. M. Ryan, P. W. Muggleton, Cynthia H. O'callaghan, R. D. Foord

Publikováno v: The Journal of Antibiotics. 29:29-37

Cefuroxime is a new broad spectrum cephalosporin antibiotic for administration by injection. It is stable to most beta-lactamases. It is active against gram-positive organisms, including penicillinase-producing staphylococci, and has wide activity ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a129694f6047055acf51515b4016dfb1
https://doi.org/10.7164/antibiotics.29.29

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Cephalexin and Oxytetracycline Compared by Double-Blind Trial in the Treatment of Bronchitis in General Practice

Autor: R. D. Foord, Brenda M. Mullinger

Publikováno v: Current Medical Research and Opinion. 2:356-365

SummaryIn a double-blind multi-centre trial conducted among general practices, cephalexin and oxytetracycline were compared for the treatment of bronchitis. The dosage, 250 mg. q.d.s.for 10 days, was the same for both drugs; if necessary the dose cou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c676c145cfabec4bd493bfc6dc0f5a0e
https://doi.org/10.1185/03007997409114771

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Cephalexin dosage in general practice assessed by double-blind trial

Autor: Susan E. Johnson, R. D. Foord

Publikováno v: Current Medical Research and Opinion. 1:37-48

SummaryIn a double-blind multicentre trial conducted in general practice, 851 adult patients were treated with either cephalexin (‘Ceporex’) tablets 250 mg. or 500 mg. q.d.s. for 7 days. The trial included the common infections, excepting pneumon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5ff9d48d4429a76a87b876d30db5e6
https://doi.org/10.1185/03007997209111143

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Cephaloridine, cephalothin and the kidney

Autor: R. D. Foord

Publikováno v: The Journal of antimicrobial chemotherapy. 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892ad5dd035fde7c034483cdfd969f4d
https://pubmed.ncbi.nlm.nih.gov/1201976

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Effect of timing of cefuroxime dosage on its protection of rats against gentamicin nephrotoxicity

Autor: G. G. Patterson, R. M. Atkinson, I. W. Harman, J. M. Wheeldon, D. A. H. Pratt, R. D. Foord, K. Capel-Edwards

Publikováno v: Infection. 8(1)

The neophrotoxic effect on rats of once daily treatment with 40 or 45 mg gentamicin/kg/day for ten days was substantially reduced by administration of 4 g cefuroxime/kg/day, either at the same time or eight hours later. This dosage of cefuroxime was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a250ad28e43e26aa6a78d7e665ed615
https://pubmed.ncbi.nlm.nih.gov/7372356

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Cefuroxime: human pharmacokinetics

Autor: R. D. Foord

Publikováno v: Antimicrobial agents and chemotherapy. 9(5)

Single doses of cefuroxime, a new parenteral cephalosporin, were given to 44 normal male subjects. Doses of 0.25, 0.5, 0.75, or 1.0 g were given intramuscularly to 33 volunteers. Mean peak serum concentrations of 14.8, 25.7, 34.6, and 40.0 μg/ml wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a3078cb99c84df29b0fa9cb816ed35
https://pubmed.ncbi.nlm.nih.gov/949172

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