Zobrazeno 1 - 10
of 67
pro vyhledávání: '"R. D. Beauchamp"'
Autor:
R D Beauchamp, C. A. O'Mahony, David H. Berger, Daniel Albo, Raymond N. DuBois, Jinyi Shao, Hongmiao Sheng, M. Tsujii
Publikováno v:
Surgery. 126:364-370
Background: Recent investigation suggests that cyclooxygenase-2 plays an important role in colorectal carcinogenesis. Transforming growth factor-beta1 (TGF-β1) is one of the most potent stimulators of cyclooxygenase-2 expression. A key step in intes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60788f75262b669f6836a1d9c4de9a11
https://doi.org/10.1016/s0039-6060(99)70178-9
https://doi.org/10.1016/s0039-6060(99)70178-9
Autor:
Sanjeev Sabharwal, D M Jakubec, R D Beauchamp, W G Mackenzie, Stephen J. Tredwell, J G LeBlanc, R Cairns
Publikováno v:
Journal of Pediatric Orthopaedics. 17:303-310
Thirteen (3.2%) of 410 patients seen in British Columbia's Children's Hospital in Vancouver from January 1984 to September 1992 with supracondylar fractures did so with an absence of a radial pulse in an otherwise well perfused hand. A combination of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fee773203e87f22cc110b7736c771848
https://doi.org/10.1097/01241398-199705000-00007
https://doi.org/10.1097/01241398-199705000-00007
Autor:
Hongmiao Sheng, P Isakson, Raymond N. DuBois, S C Kirkland, Jinyi Shao, Jason D. Morrow, Robert J. Coffey, R D Beauchamp
Publikováno v:
Journal of Clinical Investigation. 99:2254-2259
A considerable amount of evidence collected from several different experimental systems indicates that cyclooxygenase-2 (COX-2) may play a role in colorectal tumorigenesis. Large epidemiologic studies have shown a 40-50% reduction in mortality from c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf72b09c5d04edb8506dc0f87c25238
https://doi.org/10.1172/jci119400
https://doi.org/10.1172/jci119400
Autor:
Raymond N. DuBois, Laura W. Lamps, A. Radhika, T Zhang, Lillian B. Nanney, Christopher S. Williams, C Luongo, R D Beauchamp
Publikováno v:
Gastroenterology. 111:1134-1140
Background & Aims: Mutations in the APC gene result C57BL/6J mice were treated with ethylnitrosourea and in an increased propensity to develop intestinal neopla- bred for transmission of germline mutations. A line was sia; however, a complete underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c24f8c1ad424c0ca0c9f587f4079517
https://doi.org/10.1016/s0016-5085(96)70083-5
https://doi.org/10.1016/s0016-5085(96)70083-5
Publikováno v:
Annals of Surgery. 223:620-628
Objective The p21 Cip1 protein is a potent stoichiometric inhibitor of cyclin-dependent kinase activity, and p21 Cip1 mRNA expression is localized to the nonproliferative compartment of the intestinal villus, suggesting an in vivo growth-inhibitory r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901805215b4e9f34f72f5bbe0a44a85d
https://doi.org/10.1097/00000658-199605000-00018
https://doi.org/10.1097/00000658-199605000-00018
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 268:E1199-E1204
The purposes of this study were to determine the regulation of insulin-like growth factor binding protein-2 (IGFBP-2) in IEC-6 cells by transforming growth factor-beta 1 (TGF-beta 1) and insulin and to determine whether IGFBP-2 mediated the growth-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca7e2ee71f17df37ec8e3f139187c59
https://doi.org/10.1152/ajpendo.1995.268.6.e1199
https://doi.org/10.1152/ajpendo.1995.268.6.e1199
Autor:
Courtney M. Townsend, R. D. Beauchamp
Publikováno v:
Current Opinion in Gastroenterology. 11:36-42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a3559d3606f79858aa04c6d56bb6a2f
https://doi.org/10.1097/00001574-199501000-00008
https://doi.org/10.1097/00001574-199501000-00008
Publikováno v:
Pancreas. 9:657-661
Lovastatin, an inhibitor of the rate-limiting enzyme of cholesterol synthesis, inhibits growth of pancreatic cancer cells. A possible mechanism of this inhibition is that lovastatin inhibits the activity of RAS protein by depleting farnesyl (an inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4300d885e826f56a16ac8dabeb31c82d
https://doi.org/10.1097/00006676-199409000-00018
https://doi.org/10.1097/00006676-199409000-00018
Autor:
Sun Kim, George H. Greeley, B. Haber, Jin Ishizuka, Srinivasan Rajaraman, R. D. Beauchamp, George Karp, Dilipkumar Parekh, Courtney M. Townsend, James C. Thompson
Publikováno v:
Pancreas. 9:83-90
The study of functioning human endocrine tumors has been hampered by a lack of suitable in vitro models. We have established the first permanent cell line of a human pancreatic carcinoid tumor (BON) in culture. BON cells grow in monolayer culture and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b050df4031ffc12061bb76836bb30110
https://doi.org/10.1097/00006676-199401000-00013
https://doi.org/10.1097/00006676-199401000-00013
Autor:
R D, Beauchamp
Publikováno v:
Canadian family physician Medecin de famille canadien. 36
The primary care physician plays a critical role in reassuring parents about their child's orthopedic development in the lower extremity. Paramount to this reassurance is the ability to understand the normal and natural history of lower extremity dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9457fc5becd94598a0e73991a51985b9
https://pubmed.ncbi.nlm.nih.gov/21233928
https://pubmed.ncbi.nlm.nih.gov/21233928