Zobrazeno 1 - 10
of 6 038
pro vyhledávání: '"R. Curtis"'
Pleiotropy in FOXC1-attributable phenotypes involves altered ciliation and cilia-dependent signaling
Autor:
Serhiy Havrylov, Paul Chrystal, Suey van Baarle, Curtis R. French, Ian M. MacDonald, Jagannadha Avasarala, R. Curtis Rogers, Fred B. Berry, Tsutomu Kume, Andrew J. Waskiewicz, Ordan J. Lehmann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Alterations to cilia are responsible for a wide range of severe disease; however, understanding of the transcriptional control of ciliogenesis remains incomplete. In this study we investigated whether altered cilia-mediated signaling contrib
Externí odkaz:
https://doaj.org/article/8843ebf9864f45db9e54d99a6ed394bb
Autor:
James Chettle, Raymond J. Louie, Olivia Larner, Robert Best, Kevin Chen, Josephine Morris, Zinaida Dedeic, Anna Childers, R. Curtis Rogers, Barbara R. DuPont, Cindy Skinner, Sébastien Küry, Kevin Uguen, Marc Planes, Danielle Monteil, Megan Li, Aviva Eliyahu, Lior Greenbaum, Nofar Mor, Thomas Besnard, Bertrand Isidor, Benjamin Cogné, Alyssa Blesson, Anne Comi, Ingrid M. Wentzensen, Blake Vuocolo, Seema R. Lalani, Roberta Sierra, Lori Berry, Kent Carter, Stephan J. Sanders, Sarah P. Blagden
Publikováno v:
HGG Advances, Vol 5, Iss 4, Pp 100345- (2024)
Summary: Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) that affects approximately 4% of males and 1% of females in the United States. While causes of ASD are multi-factorial, single rare genetic variants contribute to around 2
Externí odkaz:
https://doaj.org/article/e0e49cd5da4340678f3756e671807267
Publikováno v:
PeerJ, Vol 12, p e17594 (2024)
The disruption in daily activity performance during COVID-19 lockdowns is widely understood to have impacted health, but a better understanding of how restricted performance of specific activities are associated with health is needed. This cross-sect
Externí odkaz:
https://doaj.org/article/38d756e041034208829946fb90d4ce98
Autor:
Erik Skovenborg, R. Curtis Ellison
Publikováno v:
OENO One, Vol 58, Iss 2 (2024)
Clinicians worldwide continually have to respond to questions about the potential benefits on health from the moderate consumption of alcohol, and the “French paradox” has often been cited as supporting this premise. We wish to briefly comment on
Externí odkaz:
https://doaj.org/article/a34d7a4fd3854b289e5121865204516d
Autor:
Gha Young Lee, Chen Yao, Shih-Jen Hwang, Jiantao Ma, Roby Joehanes, Dong Heon Lee, R. Curtis Ellison, Lynn L. Moore, Chunyu Liu, Daniel Levy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Rheumatoid arthritis (RA) is a risk factor for atherosclerotic cardiovascular diseases (CVD). Given the critical roles of the immune system and inflammatory signals in the pathogenesis of CVD, we hypothesized that interrogation of CVD-relate
Externí odkaz:
https://doaj.org/article/fe95c63e1b5b42a69e23b7afe79fe578
Autor:
Margaret Meador, Fátima Coronado, Debosree Roy, R. Curtis Bay, Joy H. Lewis, Jessica Chen, Rachel Cheung, Christopher Utman, Judith A. Hannan
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Uncontrolled hypertension is a leading risk factor for cardiovascular disease. To ensure continuity of care, community health centers (CHCs) nationwide implemented virtual care (telehealth) during the pandemic. CHCs use the Center
Externí odkaz:
https://doaj.org/article/3bc4e9747bd84d968a4d8c6491f34f08
Autor:
Katy Phelan, Luigi Boccuto, Craig M. Powell, Tobias M. Boeckers, Conny van Ravenswaaij-Arts, R. Curtis Rogers, Carlo Sala, Chiara Verpelli, Audrey Thurm, William E. Bennett, Christopher J. Winrow, Sheldon R. Garrison, Roberto Toro, Thomas Bourgeron
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-4 (2022)
Abstract Phelan-McDermid syndrome (PMS) was initially called the 22q13 deletion syndrome based on its etiology as a deletion of the distal long arm of chromosome 22. These included terminal and interstitial deletions, as well as other structural rear
Externí odkaz:
https://doaj.org/article/399efd35b13d49aca4c80ce2e31e1dfa
Autor:
Xuemei Shi, Daniel Moats, Daniel Magner, Anna Childers, Meg Keating, R. Curtis Rogers, Jennifer Lee
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100605- (2023)
Externí odkaz:
https://doaj.org/article/8c7db9fc46fb47c1a1afc692eac89e7b
Autor:
Samantha M. Carlisle, Hongwei Qin, R. Curtis Hendrickson, Jordana E. Muwanguzi, Elliot J. Lefkowitz, Richard E. Kennedy, Zhaoqi Yan, Talene A. Yacoubian, Etty N. Benveniste, Andrew B. West, Ashley S. Harms, David G. Standaert
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Increasing evidence supports the role of brain and systemic inflammation in the etiology of Parkinson disease (PD). We used gene expression profiling to examine the activation state of peripheral blood monocytes in 18 patients with early, un
Externí odkaz:
https://doaj.org/article/05be2d31917548968fb8f99ff6f9f339
Autor:
Taraswi Mitra Ghosh, Jason White, Joshua Davis, Suman Mazumder, Teeratas Kansom, Elena Skarupa, Grafton S. Barnett, Gary A. Piazza, R. Curtis Bird, Amit K. Mitra, Clayton Yates, Brian S. Cummings, Robert D. Arnold
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Repetitive, low-dose (metronomic; METRO) drug administration of some anticancer agents can overcome drug resistance and increase drug efficacy in many cancers, but the mechanisms are not understood fully. Previously, we showed that METRO dosing of to
Externí odkaz:
https://doaj.org/article/78bf5631e26f44058e9dd33c413cb9f1