Zobrazeno 1 - 10
of 123
pro vyhledávání: '"R. Cursio"'
Autor:
Pierre Gounon, Patrick Auberger, R. Cursio, Pascal Colosetti, Jean Gugenheim, Antonio Iannelli, S. Pagnotta, Marie-Christine Saint-Paul
Publikováno v:
Transplantation Proceedings. 42:3977-3980
Normothermic liver ischemia-reperfusion (I-R) may induce hepatocellular autophagy, apoptosis, and necrosis. The aim of this study was to investigate these three types of cell death in normothermic liver I-R in rats. A segmental normothermic ischemia
Publikováno v:
Transplantation Proceedings 28 (2008): 5634–5645.
info:cnr-pdr/source/autori:Cursio R, Miele C, Filippa N, Van Obberghen E, Gugenheim J./titolo:Liver HIF-1 alpha induction precedes apoptosis following normothermic ischemia-reperfusion in rats./doi:/rivista:Transplantation Proceedings/anno:2008/pagina_da:5634/pagina_a:5645/intervallo_pagine:5634–5645/volume:28
info:cnr-pdr/source/autori:Cursio R, Miele C, Filippa N, Van Obberghen E, Gugenheim J./titolo:Liver HIF-1 alpha induction precedes apoptosis following normothermic ischemia-reperfusion in rats./doi:/rivista:Transplantation Proceedings/anno:2008/pagina_da:5634/pagina_a:5645/intervallo_pagine:5634–5645/volume:28
Apoptosis plays an important role in ischemia-reperfusion (I-R) injury during liver transplantation. The hypoxia-inducible factor alpha (HIF-1alpha) may trigger liver apoptosis following I-R through the induction of hypoxically regulated genes. The a
Autor:
Jean Gugenheim, Bernard Rossi, Annie Schmid-Alliana, Alaa El-Ghoneimi, Michel Tovey, Michiels Jf, R. Cursio, Ahmed Lasfar
Publikováno v:
HPB. 9(2):112-119
Background: Pentoxifylline (PTX) has been shown to reduce hepatic injury after normothermic ischemia and reperfusion (I-R) in rat liver. Aim: The aim of this study was to evaluate the effects of PTX on liver expression of tumor necrosis factor alpha
Autor:
Emmanuel Van Obberghen, Claudia Miele, Patrick Auberger, Pascal Colosetti, R. Cursio, Jean Gugenheim, N. Filippa
Publikováno v:
Journal of Surgical Research. 125:30-36
Background The aim of this study was to evaluate the role of the pro-apoptotic molecule Fas Ligand (FasL) in 120 min normothermic ischemia-reperfusion (I-R) induced apoptosis in rat liver treated or not with Z-Asp-cmk caspase inhibitor. Materials and
Autor:
Jean Gugenheim, Annie Schmid-Alliana, Marina Laurens, Marie Christine Saint-Paul, R. Cursio, Catherine Heurteaux, Dominique Crenesse
Publikováno v:
European Journal of Pharmacology. 473:177-184
The aim of this study was to demonstrate that tacrolimus (FK506) has a hepatoprotective effect by reducing ischemia-reperfusion-induced apoptosis and necrosis, both of which lead to post-surgical liver dysfunction. An ischemia-reperfusion model and p
Autor:
Jean-Michel Antoine, Daniel Balas, Francoise Senegas-Balas, Chantal Cayuela, Nathalie Rolf-Petersen, R. Cursio, Benoît Foligné
Publikováno v:
Digestive Diseases and Sciences. 48:1147-1158
Previous study pointed to an important role of adrenals and glucocorticoids in the trophic status of the adult small intestine mucosa, with possible implications during stress events. Small intestine morphological and biochemical consequences of 10-d
Autor:
Karine Tornieri, Jean Gugenheim, Annie Schmid-Alliana, Catherine Heurteaux, Dominique Crenesse, R. Cursio, Marina Laurens
Publikováno v:
Pharmacology. 65:87-95
Interruption of hepatic blood flow is necessary in surgery, but the liver is sensitive to ischemia and reperfusion. Hypoxia induces an increase in intracellular calcium concentration. In previous studies, we have shown that hypoxia-reoxygenation (H/R
Autor:
Virginie Bottero, Vincent Dive, Bernard Mari, Athanasios Yiotakis, Philippe Rostagno, Patrick Auberger, Jean Gugenheim, Marie-Christine Saint-Paul, R. Cursio, Patrick Anglard, Krystel Louis, Jean Giudicelli
Publikováno v:
The FASEB Journal. 16:1-24
Hepatic ischemia occurs in liver transplantation, hemodynamic or cardiogenic shock, and liver resection associated with trauma or tumor. Ischemia/reperfusion (I/R) injury results in microcirculation failure followed by apoptosis and necrosis. Matrix
Autor:
R. Cursio, Annie Schmid-Alliana, Bernard Rossi, Dominique Crenesse, Jean Gugenheim, Catherine Heurteaux, Marina Laurens
Publikováno v:
Hepatology. 34:972-978
Prolonged liver ischemia followed by reperfusion (I/R) causes functional and structural damage to liver cells, resulting in necrosis and apoptosis. c-jun N-terminal kinase 1/stress-activated protein kinase 1 (JNK(1)/SAPK(1)) is activated during I/R a
Autor:
R. Cursio
Publikováno v:
HPB. 12:1-3
During transplantation, the liver is subjected to ischaemia and reperfusion (I-R) injury at three distinct stages. The first, when the liver is explanted from the donor and stored on ice at 0° to 4°C, is a variable but generally long period of cold