Peptide-Tetrapyrrole Supramolecular Self-Assemblies: State of the Art

Autor: Paolo Dognini, Christopher R. Coxon, Wendel A. Alves, Francesca Giuntini

Publikováno v: Molecules, Vol 26, Iss 3, p 693 (2021)

The covalent and noncovalent association of self-assembling peptides and tetrapyrroles was explored as a way to generate systems that mimic Nature’s functional supramolecular structures. Different types of peptides spontaneously assemble with porph

Externí odkaz: https://doaj.org/article/433f082a8b404dbd9ae4297023244ca8

Flavonoid-based inhibitors of the Phi-class glutathione transferase from black-grass to combat multiple herbicide resistance

Autor: Melissa Brazier-Hicks, Maria Schwarz, Glynn Mitchell, Robert Edwards, Ian Cummins, David J. Wortley, Patrick G. Steel, Hannah E. Straker, David John Hughes, Rebecca Florence Mary Eno, Christopher R. Coxon, Ehmke Pohl, Jenny Moore, Nawaporn Onkokesung, Stefanie Freitag-Pohl

Publikováno v: Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, 2021, Vol.19(42), pp.9211-9222 [Peer Reviewed Journal]
Schwarz, M, Eno, R F M, Freitag-Pohl, S, Coxon, C R, Straker, H E, Wortley, D J, Hughes, D J, Mitchell, G, Moore, J, Cummins, I, Onkokesung, N, Brazier-Hicks, M, Edwards, R, Pohl, E & Steel, P G 2021, ' Flavonoid-based inhibitors of the Phi-class glutathione transferase from black-grass to combat multiple herbicide resistance ', Organic and Biomolecular Chemistry, vol. 19, no. 42, pp. 9211-9222 . https://doi.org/10.1039/d1ob01802g

The evolution and growth of multiple-herbicide resistance (MHR) in grass weeds continues to threaten global cereal production. While various processes can contribute to resistance, earlier work has identified the phi class glutathione-S-transferase (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8051da3d36f1de2ecdfeeb4677109416
https://doi.org/10.1039/d1ob01802g

Graphene-wrapped sulfur/metal organic framework-derived microporous carbon composite for lithium sulfur batteries

Autor: Renjie Chen, Teng Zhao, Tian Tian, Shuai Cao, Paul R. Coxon, Kai Xi, David Fairen-Jimenez, R. Vasant Kumar, Anthony K. Cheetham

Publikováno v: APL Materials, Vol 2, Iss 12, Pp 124109-124109-7 (2014)

A three-dimensional hierarchical sandwich-type graphene sheet-sulfur/carbon (GS-S/CZIF8-D) composite for use in a cathode for a lithium sulfur (Li-S) battery has been prepared by an ultrasonic method. The microporous carbon host was prepared by a one

Externí odkaz: https://doaj.org/article/d662fbc3a7d44491a1e8f23e8d020e46

Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles

Autor: Amos A. Fatokun, Christopher R. Coxon, Touraj Ehtezazi, Muttuswamy Sivakumaran, Meritxell Teixidò, Yamir Islam, J. E. G. Downing, Andrew G. Leach, Stefano Pluchino, Jayden Smith

Publikováno v: Islam, Y, Leach, A G, Smith, J, Pluchino, S, Coxon, C R, Sivakumaran, M, Downing, J, Fatokun, A A, Teixidò, M & Ehtezazi, T 2021, ' Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles ', Advanced Science . https://doi.org/10.1002/advs.202002085
Advanced Science, Vol 8, Iss 11, Pp n/a-n/a (2021)
Advanced Science

The prevalence of neurological/neurodegenerative diseases, such as Alzheimer's disease is known to be increasing due to an aging population and is anticipated to further grow in the decades ahead. The treatment of brain diseases is challenging partly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d2954d8013a44213490ac9e03795ac

Simultaneous Quantification of Commonly Used Counter Ions in Peptides and Active Pharmaceutical Ingredients by Mixed Mode Chromatography and Evaporative Light Scattering Detection

Autor: Christian Steuer, Alessandro Streuli, Christopher R. Coxon

Publikováno v: Journal of pharmaceutical sciences. 110(8)

In academia and industry, the analysis of counter ions in small molecules and synthetic peptides represents a great challenge. Due to the frequent use of salt forms and the application of a wider range of counter ions in pharmaceutically used substan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3ef809077585498e5c7705ed19b07b
https://pubmed.ncbi.nlm.nih.gov/33864781