Zobrazeno 1 - 10
of 55
pro vyhledávání: '"R. Clark Brown"'
Autor:
Seung Yup Lee, Rowan O. Brothers, Katherine B. Turrentine, Ayesha Quadri, Eashani Sathialingam, Kyle R. Cowdrick, Scott Gillespie, Shasha Bai, Adam E. Goldman-Yassen, Clinton H. Joiner, R. Clark Brown, Erin M. Buckley
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Red blood cell transfusions are common in patients with sickle cell disease who are at increased risk of stroke. Unfortunately, transfusion thresholds needed to sufficiently dilute sickle red blood cells and adequately restore oxygen delivery to the
Externí odkaz:
https://doaj.org/article/d446c58df80744be877738ac69533f49
Autor:
Stella T. Chou, Jonathan M. Flanagan, Sunitha Vege, Naomi L.C. Luban, R. Clark Brown, Russell E. Ware, Connie M. Westhoff
Publikováno v:
Blood Advances, Vol 1, Iss 18, Pp 1414-1422 (2017)
Abstract: RH genes are highly polymorphic and encode the most complex of the 35 human blood group systems. This genetic diversity contributes to Rh alloimmunization in patients with sickle cell anemia (SCA) and is not avoided by serologic Rh-matched
Externí odkaz:
https://doaj.org/article/f015d3504c7143288d2f205f62b428dc
Autor:
Julie Kanter, R. Clark Brown, Cynthia Norris, Santosh M. Nair, Abdullah Kutlar, Deepa Manwani, Nirmish Shah, Chiaki Tanaka, Shankaranand Bodla, Gessami Sanchez-Olle, Urs Albers, Darla Liles
Publikováno v:
Blood Advances. 7:943-952
Crizanlizumab is an anti–P-selectin monoclonal antibody indicated to reduce the frequency/prevent recurrence of vaso-occlusive crises (VOCs) in patients with sickle cell disease (SCD) aged ≥16 years. This analysis of an ongoing phase 2, nonrandom
Autor:
Carlton D. Dampier, Marilyn Jo Telen, Ted Wun, R. Clark Brown, Payal Desai, Fuad El Rassi, Beng Fuh, Julie Kanter, Yves Pastore, Jennifer Rothman, James G. Taylor, David Readett, Krupa M. Sivamurthy, Brinda Tammara, Li-Jung Tseng, Jay Nelson Lozier, Helen Thackray, John L. Magnani, Kathryn L. Hassell
Publikováno v:
Blood. 141:168-179
The efficacy and safety of rivipansel, a predominantly E-selectin antagonist, were studied in a phase 3, randomized, controlled trial for vaso-occlusive crisis (VOC) requiring hospitalization (RESET). A total of 345 subjects (204 adults and 141 child
Publikováno v:
British journal of haematologyREFERENCES. 199(4)
Autor:
Monica L. Hulbert, Deepa Manwani, Emily Riehm Meier, Ofelia A. Alvarez, R. Clark Brown, Michael U. Callaghan, Andrew D. Campbell, Thomas D. Coates, Melissa J. Frei‐Jones, Jane S. Hankins, Matthew M. Heeney, Lewis L. Hsu, Jeffrey D. Lebensburger, Charles T. Quinn, Nirmish Shah, Kim Smith‐Whitley, Courtney Thornburg, Julie Kanter
Publikováno v:
Pediatric bloodcancerREFERENCES. 70(1)
Sickle cell disease (SCD) requires coordinated, specialized medical care for optimal outcomes. There are no United States (US) guidelines that define a pediatric comprehensive SCD program. We report a modified Delphi consensus-seeking process to dete
Autor:
Meghna Dua, Winfred C. Wang, Timothy McCavit, Suvankar Majumdar, R. Clark Brown, Zora R. Rogers, Jeffrey Gossett, Guolian Kang, Jeremie H. Estepp
Publikováno v:
Blood. 140:11108-11109
Autor:
Meghna Dua, Winfred C. Wang, R. Clark Brown, Melissa A. McNaull, Zora R. Rogers, Martha Barton, Jane Hankins, Jeffrey Gossett, Julie Richardson, Jerlym S. Porter, Guolian Kang, Jeremie H. Estepp
Publikováno v:
Blood. 140:445-446
Autor:
Santosh M Nair, Shankaranand Bodla, Gessami Sanchez-Olle, R. Clark Brown, Kim Smith-Whitley, Darla K. Liles, Chiaki Tanaka, Julie Kanter, Nirmish Shah, Urs Albers
Publikováno v:
Blood. 136:17-19
Background: SCD is an inherited blood disorder characterized by hemolytic anemia, endothelial damage and acutely painful VOCs that cause chronic and potentially life-threatening complications. P-selectin is an adhesion protein that plays a key role i
Autor:
R. Clark Brown, Mariane de Montalembert, Thu Thuy Nguyen, Raquel Merino Herranz, Yasser Wali, Du Lam, Isaac Odame, David C. Rees, Matthew M. Heeney, Julie Kanter
Publikováno v:
Blood. 136:22-24
Background: Sickle cell disease (SCD) is a group of genetic blood disorders characterized by hemolytic anemia, multi-organ damage and acutely painful events (vaso-occlusive crises [VOCs]) that can cause life-threatening complications. Vaso-occlusion