Zobrazeno 1 - 10
of 13
pro vyhledávání: '"R. Carlin Walsh"'
Autor:
Anat R. Tambur, Joseph R. Leventhal, R. Carlin Walsh, John J. Friedewald, Jennifer R. Zitzner
Publikováno v:
Transplantation. 96:1065-1072
BACKGROUND Panel-reactive antibody (PRA) testing provides assessment of the breadth of sensitization a patient might have against human leukocyte antigen (HLA) antigens. The evolution of calculated PRA (cPRA) reflects the commitment of the transplant
Autor:
Basma Sadaka, R. Carlin Walsh, Rita R. Alloway, Paul Brailey, Amit D. Tevar, Prabir Roy-Chaudhury, G. Mogilishetty, Garth E. Wall, Michael Cardi, E. Steve Woodle, Alin Girnita, A. R. Shields, Amit Govil
Publikováno v:
Transplantation. 91:1218-1226
Background. The efficacy of plasma cell targeted therapies for antibody-mediated rejection (AMR) has not been defined in detail. The purpose of this study was to compare early and late acute AMR in terms of immunologic characteristics and responses w
Autor:
Lois J. Arend, Paul Brailey, G. Mogilishetty, A. H. Rike, Amit Govil, Prabir Roy-Chaudhury, E. Steve Woodle, Rita R. Alloway, R. Carlin Walsh, J Everly
Publikováno v:
Transplantation. 89:277-284
Background Rapid and complete elimination of donor-specific anti-human leukocyte antigen antibodies (DSA) during antibody-mediated rejection (AMR) is rarely achieved with traditional antihumoral therapies. Proteasome inhibitor-based therapy has been
Publikováno v:
Current Opinion in Organ Transplantation. 14:662-666
The purpose of this review is to describe the biochemistry and physiology of proteasome inhibition and to discuss recent studies with proteasome inhibitor therapy in organ transplantation.Traditional antihumoral therapies do not deplete plasma cells,
Autor:
John J. Friedewald, Joseph R. Leventhal, R. Carlin Walsh, Jennifer R. Zitzner, Anat R. Tambur
Publikováno v:
Transplantation. 95(4)
Background. The United Network for Organ Sharing algorithm for deceased-donor kidney allocation considers only the human leukocyte antigen (HLA)-A, HLA-B, and HLA-DR loci. Although HLA-DQ serologic specificities can be entered as unacceptable antigen
Autor:
E. Steve Woodle, Alin Girnita, A. R. Shields, Dennis J. Hanseman, R. Carlin Walsh, Basma Sadaka, Nicole M. Schmidt, Rita R. Alloway
Publikováno v:
Transplantation. 94(4)
Background A prospective intermediate-term evaluation of toxicities associated with bortezomib therapy for antibody-mediated rejection (AMR) and desensitization was conducted. Methods Patients were graded for bortezomib-related toxicities: hematologi
Autor:
Amit, Govil, R Carlin, Walsh, Amit, Tevar, Rita, Alloway, Prabir, Roy-Chaudhury, Gautham, Mogilishetty, Garth E, Wall, Paul, Brailey, Alin, Girnita, E Steve, Woodle
Publikováno v:
Clinical transplants.
This report presents the first experience with plasma cell-targeted therapy in treating antibody mediated rejection in pancreas transplant recipients. In this experience, bortezomib provided results similar to those previously reported in kidney tran
Publikováno v:
Human Immunology. 74:494-495
Aim Single antigen reagent panels differ in the makeup of HLA alleles offered for testing. Additional alleles (2 HLADR, 7 HLA-DQ) were added for the newest lot of Gen-Probe MHC Class II reagents in an effort to improve diversity of the panel and incr
Publikováno v:
Human Immunology. 74:130
Aim To evaluate and validate utilization of the more sensitive engraftment monitoring method, real-time quantitative polymerase chain reaction (qPCR), in detecting chimerism levels during early stages of relapse or rejection. Methods Twenty-four samp
Publikováno v:
Human Immunology. 74:43
Aim Donor specific HLA antibodies (DSA) in liver transplant recipients have been associated with allograft dysfunction. This analysis aims to describe the clinical outcomes in simultaneous liver-kidney (SLK) recipients with and without HLA antibodies