Zobrazeno 1 - 10
of 785
pro vyhledávání: '"R. Cairns"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Neuronal nitric oxide synthase (nNOS) neurons play a fundamental role in inhibitory neurotransmission, within the enteric nervous system (ENS), and in the establishment of gut motility patterns. Clinically, loss or disruption of nNOS neurons
Externí odkaz:
https://doaj.org/article/d058b11d002948a896fc02e04aee5f40
Autor:
Graham JM Hickey, Candice L Wike, Xichen Nie, Yixuan Guo, Mengyao Tan, Patrick J Murphy, Bradley R Cairns
Publikováno v:
eLife, Vol 11 (2022)
Vertebrate embryos achieve developmental competency during zygotic genome activation (ZGA) by establishing chromatin states that silence yet poise developmental genes for subsequent lineage-specific activation. Here, we reveal the order of chromatin
Externí odkaz:
https://doaj.org/article/0f077f5c7e104e5a86be865a70d5caec
Autor:
Haiqi Chen, Evan Murray, Anubhav Sinha, Anisha Laumas, Jilong Li, Daniel Lesman, Xichen Nie, Jim Hotaling, Jingtao Guo, Bradley R. Cairns, Evan Z. Macosko, C. Yan Cheng, Fei Chen
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109915- (2021)
Summary: Single-cell RNA sequencing has revealed extensive molecular diversity in gene programs governing mammalian spermatogenesis but fails to delineate their dynamics in the native context of seminiferous tubules, the spatially confined functional
Externí odkaz:
https://doaj.org/article/a14b6b9f7c6f49fcbea7513571e4a8d5
Publikováno v:
Flexible Flat Panel Displays. :337-350
Publikováno v:
Flexible Flat Panel Displays. :255-270
Autor:
Darran R. Cairns, Anthony S. Weiss
Publikováno v:
Flexible Flat Panel Displays. :287-300
Autor:
Patrick J Murphy, Jingtao Guo, Timothy G Jenkins, Emma R James, John R Hoidal, Thomas Huecksteadt, Dallin S Broberg, James M Hotaling, David F Alonso, Douglas T Carrell, Bradley R Cairns, Kenneth I Aston
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008756 (2020)
Paternal cigarette smoke (CS) exposure is associated with increased risk of behavioral disorders and cancer in offspring, but the mechanism has not been identified. Here we use mouse models to investigate mechanisms and impacts of paternal CS exposur
Externí odkaz:
https://doaj.org/article/f1c39d09b6eb4aa9abd6df5fcde7696e
Publikováno v:
eLife, Vol 9 (2020)
SWI/SNF-family chromatin remodeling complexes, such as S. cerevisiae RSC, slide and eject nucleosomes to regulate transcription. Within nucleosomes, stiff DNA sequences confer spontaneous partial unwrapping, prompting whether and how SWI/SNF-family r
Externí odkaz:
https://doaj.org/article/1e3be44cef52403c94493ea6187be6ec
Publikováno v:
Flexible Flat Panel Displays. :1-3
Autor:
Edward J. Grow, Ying Liu, Zhiqiang Fan, Iuri Viotti Perisse, Tayler Patrick, Misha Regouski, Sean Shadle, Irina Polejaeva, Kenneth L. White, Bradley R. Cairns
Publikováno v:
bioRxiv
Reprogramming of the gamete into a developmentally competent embryo identity is a fundamental aspect of preimplantation development. One of the most important processes of this reprogramming is the transcriptional awakening during embryonic genome ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9476acc51ea565dd3e153415513692c8
https://europepmc.org/articles/PMC10120652/
https://europepmc.org/articles/PMC10120652/