Zobrazeno 1 - 10
of 935
pro vyhledávání: '"R. CROWLEY"'
Autor:
Zackery E Plyler, Christopher W McAtee, Aubrey E Hill, Michael R Crowley, Janice M Tindall, Samuel R Tindall, Disha Joshi, Eric J Sorscher
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303257 (2024)
Patterns of single nucleotide polymorphisms (SNPs) in eukaryotic DNA are traditionally attributed to selective pressure, drift, identity descent, or related factors-without accounting for ways in which bias during de novo SNP formation, itself, might
Externí odkaz:
https://doaj.org/article/9af081f218c24a57bacb27a06f5326c0
Autor:
Andrew R. Crowley, Matthew R. Mehlenbacher, Mohammad M. Sajadi, Anthony L. DeVico, George K. Lewis, Margaret E. Ackerman
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTAntibody-mediated effector functions are widely considered to unfold according to an associative model of IgG-Fcγ receptor (FcγR) interactions. The associative model presupposes that Fc receptors cannot discriminate antigen-bound IgG from f
Externí odkaz:
https://doaj.org/article/5559437caf7c436bac7eade70d7f9afd
Autor:
Matthew J. Sullivan, Darren Prince, Kelvin G. K. Goh, Lahiru Katupitiya, Dean Gosling, Michael R. Crowley, David K. Crossman, Glen C. Ulett
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Streptococcus agalactiae, also known as Group B Streptococcus (GBS) is a frequent cause of infections, including bacteraemia and other acute diseases in adults and immunocompromised individuals. We developed a novel system to study GBS withi
Externí odkaz:
https://doaj.org/article/ba104a9df20644099df98bfad98b3b28
Autor:
Nikita Bhalerao, Asmi Chakraborty, Michael P. Marciel, Jihye Hwang, Colleen M. Britain, Austin D. Silva, Isam E. Eltoum, Robert B. Jones, Katie L. Alexander, Lesley E. Smythies, Phillip D. Smith, David K. Crossman, Michael R. Crowley, Boyoung Shin, Laurie E. Harrington, Zhaoqi Yan, Maigen M. Bethea, Chad S. Hunter, Christopher A. Klug, Donald J. Buchsbaum, Susan L. Bellis
Publikováno v:
JCI Insight, Vol 8, Iss 19 (2023)
The role of aberrant glycosylation in pancreatic ductal adenocarcinoma (PDAC) remains an under-investigated area of research. In this study, we determined that ST6 β-galactoside α2,6 sialyltransferase 1 (ST6GAL1), which adds α2,6-linked sialic aci
Externí odkaz:
https://doaj.org/article/8d74b6365a7e4f5aab8310300004ced9
Publikováno v:
Frontiers in Nuclear Medicine, Vol 3 (2023)
BackgroundThe nuclear medicine community has stated that they are using best practices to gain venous access and administer radiopharmaceuticals, and therefore do not contribute to extravasations. We tested this hypothesis qualitatively and quantitat
Externí odkaz:
https://doaj.org/article/d22cacd17d184ba692ad3ec49d38b69a
Autor:
Alex Yashchenko, Sarah J. Bland, Cheng J. Song, Ummey Khalecha Bintha Ahmed, Rachel Sharp, Isabella G. Darby, Audrey M. Cordova, Morgan E. Smith, Jeremie M. Lever, Zhang Li, Ernald J. Aloria, Shuja Khan, Bibi Maryam, Shanrun Liu, Michael R. Crowley, Kenneth L. Jones, Lauren A. Zenewicz, James F. George, Michal Mrug, David K. Crossman, Katharina Hopp, Stavros Stavrakis, Mary B. Humphrey, Florent Ginhoux, Kurt A. Zimmerman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Kidney macrophages are comprised of both monocyte-derived and tissue resident populations; however, the heterogeneity of kidney macrophages and factors that regulate their heterogeneity are poorly understood. Herein, we performed single cell RNA sequ
Externí odkaz:
https://doaj.org/article/33bd5d09e8bc4889bac131cdfd30c35a
Autor:
Rudradip Pattanayak, Rachel Underwood, Michael R. Crowley, David K. Crossman, Jennifer R. Morgan, Talene A. Yacoubian
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract We report an incidental 358.5 kb deletion spanning the region encoding for alpha-synuclein (αsyn) and multimerin1 (Mmrn1) in the Rab27a/Rab27b double knockout (DKO) mouse line previously developed by Tolmachova and colleagues in 2007. Weste
Externí odkaz:
https://doaj.org/article/8bd287e7d97b4036b0fcad4eede32b48
Autor:
Harini Natarajan, Shiwei Xu, Andrew R. Crowley, Savannah E. Butler, Joshua A. Weiner, Evan M. Bloch, Kirsten Littlefield, Sarah E. Benner, Ruchee Shrestha, Olivia Ajayi, Wendy Wieland-Alter, David Sullivan, Shmuel Shoham, Thomas C. Quinn, Arturo Casadevall, Andrew Pekosz, Andrew D. Redd, Aaron A. R. Tobian, Ruth I. Connor, Peter F. Wright, Margaret E. Ackerman
Publikováno v:
BMC Immunology, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background While antibodies can provide significant protection from SARS-CoV-2 infection and disease sequelae, the specific attributes of the humoral response that contribute to immunity are incompletely defined. Methods We employ machine le
Externí odkaz:
https://doaj.org/article/034c463115724341925f58490be90688
Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates
Autor:
Yvonne J. Rosenberg, Tracy Ordonez, Urjeet S. Khanwalkar, Philip Barnette, Shilpi Pandey, Iara M. Backes, Claire E. Otero, Benjamin S. Goldberg, Andrew R. Crowley, David A. Leib, Mariya B. Shapiro, Xiaoming Jiang, Lori A. Urban, Jonathan Lees, Ann J. Hessell, Sallie Permar, Nancy L. Haigwood, Margaret E. Ackerman
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Transplacental transfer of maternal antibodies provides the fetus and newborn with passive protection against infectious diseases. While the role of the highly conserved neonatal Fc receptor (FcRn) in transfer of IgG in mammals is undisputed
Externí odkaz:
https://doaj.org/article/25f9b49593274f65bc8c9255adb1a843
Autor:
Joseph A. Hakim, George B. H. Green, Stephen A. Watts, Michael R. Crowley, Casey D. Morrow, Asim K. Bej
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 2, Pp 978-995 (2021)
This paper describes the microbial community composition and genes for key metabolic genes, particularly the nitrogen fixation of the mucous-enveloped gut digesta of green (Lytechinus variegatus) and purple (Strongylocentrotus purpuratus) sea urchins
Externí odkaz:
https://doaj.org/article/5c1b199b43c547e89d88d61d05b3a331