Zobrazeno 1 - 10
of 47
pro vyhledávání: '"R. CASSELS"'
Publikováno v:
ACS Catalysis. 13:6518-6524
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f43bc4a8e55d98e2ab74497030a6cc55
https://doi.org/10.1021/acscatal.3c01515
https://doi.org/10.1021/acscatal.3c01515
Publikováno v:
Science
Synthetic methods that enable simultaneous control over multiple stereogenic centers are desirable for the efficient preparation of pharmaceutical compounds. Herein, we report the discovery and development of a catalyst-mediated asymmetric Michael ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ee268830d5ee5e79d6cb9821e88c21
https://pubmed.ncbi.nlm.nih.gov/35679416
https://pubmed.ncbi.nlm.nih.gov/35679416
Publikováno v:
Antimicrobial Agents and Chemotherapy. 39:1925-1933
The biological properties of SB 205952, a nitrofuryl oxazole derivative of monic acid, differ from those of the closely related antibacterial agent mupirocin. Compared with mupirocin, SB 205952 has increased antimicrobial potency, an extended spectru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092e93988b14d5ad3d4d96189873188e
https://doi.org/10.1128/aac.39.9.1925
https://doi.org/10.1128/aac.39.9.1925
Autor:
J. E. BALDWIN, R. M. ADLINGTON, J. S. BRYANS, M. D. LLOYD, T. J. SEWELL, C. J. SCHOFIELD, K. H. BAGGALEY, R. CASSELS
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::877b24ed22774b889b6a5020d143760c
https://doi.org/10.1002/chin.199243167
https://doi.org/10.1002/chin.199243167
Autor:
Elizabeth J. Lawlor, Christopher J. Schofield, Jack E. Baldwin, R. Cassels, John E. Hodgson, Matthew D. Lloyd, Stephen W. Elson, Susan Holland
Publikováno v:
ChemInform. 25
Purification and sequencing of clavaminic acid synthase (CAS) activities from S. clavuligerus SC2 provided evidence for the existence of two CAS isozymes. One of these isozymes was cloned and expressed in E. coli. The recombinant CAS isozyme was show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5a75b18ada3d6ba30864177c18e9eba
https://doi.org/10.1002/chin.199449054
https://doi.org/10.1002/chin.199449054
Autor:
Keith H. Baggaley, R. Cassels, Matthew D. Lloyd, Robert M. Adlington, Christopher J. Schofield, Timothy J. Sewell, Jack E. Baldwin, Justin S. Bryans
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0de72258df798d9040fa59285bb48199
https://doi.org/10.1002/chin.199739289
https://doi.org/10.1002/chin.199739289
Autor:
F.M. Poulsen, Robert J. P. Williams, D.E.P. Grace, Christopher M. Dobson, David Phillips, Stephen J. Perkins, Colin C.F. Blake, Louise N. Johnson, R. Cassels
Publikováno v:
Ciba Foundation Symposium 60 - Molecular Interactions and Activity in Proteins
The conformations of lysozyme in crystals and in aqueous solution are discussed and it is shown that the basic conformation is similar in the two states. Certain parts of the molecule have mobility. The reactions of lysozyme with protons, metal ions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c3251e44de5deb0c4add84cc4a362b5
https://doi.org/10.1002/9780470720424.ch10
https://doi.org/10.1002/9780470720424.ch10
Autor:
Jack E. Baldwin, Matthew D. Lloyd, John E. Hodgson, Christopher J. Schofield, Elizabeth J. Lawlor, Stephen W. Elson, Susan Holland, R. Cassels
Publikováno v:
TETRAHEDRON. 50(29)
Purification and sequencing of clavaminic acid synthase (CAS) activities from S. clavuligerus SC2 provided evidence for the existence of two CAS isozymes. One of these isozymes was cloned and expressed in E. coli. The recombinant CAS isozyme was show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b06d564fcbf6cffa08f5647c5ee63a3
http://ora.ox.ac.uk/objects/uuid:1fda5b84-5061-42d0-8512-5252308eb117
http://ora.ox.ac.uk/objects/uuid:1fda5b84-5061-42d0-8512-5252308eb117
Autor:
R. Cassels, R.A.G. Smith
Publikováno v:
Fibrinolysis. 2:189-195
A hydrolytically reversible conjugate of human non-specific immunoglobulin G linked to the active centre serine residue of recombinant tissue-type plasminogen activator (rt-PA) was prepared. The material was synthesised by reaction of thiolated immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6258744d32a8bcaa42a7989341610c97
https://doi.org/10.1016/0268-9499(88)90012-4
https://doi.org/10.1016/0268-9499(88)90012-4
Autor:
Robert J. P. Williams, F.M. Poulsen, Keith S. Wilson, Christopher M. Dobson, R. Cassels, Colin C.F. Blake
Publikováno v:
Journal of Molecular Biology. 147:73-95
The structure of a derivative of hen egg-white lysozyme (EC 3.2.1.17) modified by N -bromosuccinimide at Trp62 has been studied by both 1 H nuclear magnetic resonance spectroscopy and X-ray crystallography. It was shown that this modification, changi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c790e61cee53b1544efce84ebe1f985
https://doi.org/10.1016/0022-2836(81)90080-2
https://doi.org/10.1016/0022-2836(81)90080-2