Výsledky vyhledávání - "R. C. Wardley"

Defective entry of herpes simplex virus types 1 and 2 into porcine cells and lack of infection in infant pigs indicate species tropism

Autor: R. C. Wardley, R. A. LeBlanc, A. O. Fuller, G. Subramanian

Publikováno v: The Journal of general virology. 76

We have determined if a defect at entry of the human pathogen herpes simplex virus type 1 (HSV-1) into cultured porcine cells extends to HSV-2 and if the poor susceptibility of porcine cells for these viruses is indicative of in vivo species tropism.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8ec57b9dc89d047ef0f0bae940d935
https://pubmed.ncbi.nlm.nih.gov/7561780

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Dose and load studies for subcutaneous and oral delivery of poly(lactide-co-glycolide) microspheres containing ovalbumin

Autor: T, Uchida, S, Martin, T P, Foster, R C, Wardley, S, Grimm

Publikováno v: Pharmaceutical research. 11(7)

Poly(lactide-co-glycolide) microspheres containing different loads of OVA (0.05, 0.1, 0.5 and 1.0% w/w) were manufactured by a w/o/w emulsion/solvent evaporation method. Low load efficiencies of less than 20% were observed. Normal size distributions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c228b62516eed636b2dcad66139ae66
https://pubmed.ncbi.nlm.nih.gov/7937541

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Genetic engineering of the pseudorabies virus genome to construct live vaccines

Autor: L E, Post, D R, Thomsen, E A, Petrovskis, A L, Meyer, P J, Berlinski, R C, Wardley

Publikováno v: Journal of reproduction and fertility. Supplement. 41

Pseudorabies virus (PRV) is a herpesvirus of pigs. Homologous recombination with plasmids offers a method to engineer precise changes in the PRV genome to produce advantageous live vaccines. Safety can be ensured by using a non-reverting deletion to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a7e6b6021462787a27326bc356c11457
https://pubmed.ncbi.nlm.nih.gov/2170641

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Feline calicivirus carrier state a study of the host/virus relationship

Autor: R. C. Wardley

Publikováno v: Archives of Virology. 52:243-249

The inter-epidemic phase of feline calicivirus was studied in a number of cats. During this period animals asymptomatically shed infective virus which was monitored at a number of sites and during different environmental conditions. Analysis of the a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51c73de4cceaccbf608c6c67fdff90a
https://doi.org/10.1007/bf01348021

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African swine fever virus

Autor: F L de Castro Portugal, J. F. Moura Nunes, J. D. Vigário, R C Wardley, D N Black, A Ordas, L Enjuanes, J Sanchez Vizcaino, C de M Andrade, W R Hess, G Thomson, C Mebus, P J Wilkinson, D Rutili

Publikováno v: Archives of Virology. 76:73-90

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07f1f6b8931fc023b6a80a6c9ddf0129
https://doi.org/10.1007/bf01311692

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The Differential Growth of Virulent and Avirulent Strains of Rinderpest Virus in Bovine Lymphocytes and Macrophages

Autor: P. B. Rossiter, R. C. Wardley

Publikováno v: Journal of General Virology. 66:969-975

Summary Rinderpest virus (RV) grew readily in cultures of purified bovine peripheral blood lymphocytes and udder macrophages. The growth of three strains of RV was compared and there appeared to be a relationship between increasing virulence and incr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb356cb76a0b152e574e4627d98627f
https://doi.org/10.1099/0022-1317-66-5-969

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Defense mechanisms against bovine herpesvirus: relationship of virus-host cell events to susceptibility to antibody-complement cell lysis

Autor: Lorne A. Babiuk, R C Wardley, Barry T. Rouse

Publikováno v: Infection and Immunity. 12:958-963

The interaction of infectious bovine rhinotracheitis virus and susceptible host cells was examined to determine whether an infected cell could be destroyed by humoral immune mechanisms before or after the transmission of virus to susceptible adjacent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb2658fe67202c28f6883ab110169e0
https://doi.org/10.1128/iai.12.5.958-963.1975

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Solid-phase radioimmunoassay techniques for the detection of African swine fever antigen and antibody

Autor: R. C. Wardley, P. J. Wilkinson, J. R. Crowther

Publikováno v: Journal of Hygiene. 83:353-361

summaryA solid phase radioimmunoassay (RIA) has been successfully developed to measure both African swine fever virus (ASFV) antigen and antibody. Studies show that the assay is reproducible and will detect limiting antigen concentrations equivalent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e3c5e38f05e3a354b8f4f6eff1ae57
https://doi.org/10.1017/s0022172400026140

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The immunological response of pigs and Guinea pigs to antigens of African swine fever virus

Autor: R C Wardley, A J Forman, P J Wilkinson

Publikováno v: Archives of Virology. 74:91-100

Pigs vaccinated with glutaraldehyde-fixed alveolar macrophages (AM) infected with African swine fever virus (ASFV) had an accelerated serological response after subsequent challenge and a slight reduction in levels of viraemia. Vaccination of pigs wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ab943affabb36ebac4fdcd3e2fe6ce
https://doi.org/10.1007/bf01314703

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