Zobrazeno 1 - 10 of 30 pro vyhledávání: '"R. C. Smallridge"'
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Cushing's syndrome due to medullary thyroid carcinoma: diagnosis by proopiomelanocortin messenger ribonucleic acid in situ hybridization
Autor: B. W. Pearson, R. C. Smallridge, William F. Young, Paul C. Carpenter, K. Bourne, J. A. van Heerden
Publikováno v: The Journal of clinical endocrinology and metabolism. 88(10)
Medullary thyroid carcinoma (MTC) rarely causes ectopic ACTH syndrome. We describe a 38-yr-old man with renal stones who had a 5-cm MTC removed in 1992. He was RET-protooncogene positive (codon 618). Serum calcitonin was 1597 pg/ml postoperatively. I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0679da56ebf7445ddce3bcc8e531fddf
https://pubmed.ncbi.nlm.nih.gov/14557423
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3
Phospholipase C activation by Na+/Ca2+ exchange is essential for monensin-induced Ca2+ influx and arachidonic acid release in FRTL-5 thyroid cells
Autor: X D, Wang, J G, Kiang, L W, Scheibel, R C, Smallridge
Publikováno v: Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 47(8)
Monensin, a Na+ ionophore, can increase cytosolic Ca2+ ([Ca2+]i) by reversing the Na+/Ca2+ exchange mechanism. This study provided additional insights into the mechanism of this Na+ ionophore-induced increase in [Ca2+]i, and emphasized the critical r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::69355d8d5263f269051d57dae471fad4
https://pubmed.ncbi.nlm.nih.gov/10510591
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4
Polymerase chain reaction-based microsatellite polymorphism analysis of follicular and Hürthle cell neoplasms of the thyroid
Autor: D L, Segev, M, Saji, G S, Phillips, W H, Westra, Y, Takiyama, S, Piantadosi, R C, Smallridge, R H, Nishiyama, R, Udelsman, M A, Zeiger
Publikováno v: The Journal of clinical endocrinology and metabolism. 83(6)
Follicular and Hürthle cell carcinomas of the thyroid cannot be differentiated from adenomas by either preoperative fine needle aspiration or intraoperative frozen section examination, and yet there exist potentially significant differences in the r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::772a4f8c1b80910797c728baa3435b64
https://pubmed.ncbi.nlm.nih.gov/9626136
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5
Heat shock gene-expression in HSP-70 and HSF1 gene-transfected human epidermoid A-431 cells
Autor: X Z, Ding, G C, Tsokos, R C, Smallridge, J G, Kiang
Publikováno v: Molecular and cellular biochemistry. 167(1-2)
Thermotolerant cells display attenuated heat shock protein 70 kD (HSP-70) gene expression and signal transduction such as intracellular Ca2+ concentration and inositol trisphosphate in response to sublethal heat. To further investigate the regulation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4be2c627e2354e26e7e958d775b2b229
https://pubmed.ncbi.nlm.nih.gov/9059991
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6
Evidence for the involvement of protein kinase C isoforms in alpha-1 adrenergic activation of phospholipase A2 in FRTL-5 thyroid cells
Autor: X D, Wang, J G, Kiang, M A, Atwa, R C, Smallridge
Publikováno v: Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 44(9)
FRTL-5 thyroid cells are a cell line extensively used for the investigation of thyroid functions. Activation of alpha-1 adrenergic receptors stimulates both arachidonic acid (AA) release and cytosolic Ca2+ increase in this cell line. Cytosolic Ca2+ a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c39f7e1f63fa14669c382cbd9e1e775c
https://pubmed.ncbi.nlm.nih.gov/9035611
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7
Increases in HSF1 translocation and synthesis in human epidermoid A-431 cells: role of protein kinase C and [Ca2+]i
Autor: X Z, Ding, R C, Smallridge, R J, Galloway, J G, Kiang
Publikováno v: Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 44(4)
It is known that heat shock increases both heat shock protein 70 kd (HSP-70) mRNA synthesis, and intracellular cytosolic free calcium concentration ([Ca2+]i). The latter enhances the heat inducible form of HSP-70 production by increasing the complex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6ddf1e1389fa0448a8105fd2e96b9a53
https://pubmed.ncbi.nlm.nih.gov/8689410
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9
Usefulness of antimicrosomal antibody titers in the diagnosis and treatment of postpartum thyroiditis
Autor: B L, Solomon, H G, Fein, R C, Smallridge
Publikováno v: The Journal of family practice. 36(2)
Postpartum thyroiditis is a common but frequently unrecognized disorder, affecting approximately 5% of women during the first 12 months after delivery. We investigated whether the antimicrosomal antibody titer could be used to determine which women w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7c1dc2f45849cc66737844b71a5b53f1
https://pubmed.ncbi.nlm.nih.gov/8426137
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10
Heat shock increases cytosolic free Ca2+ concentration via Na(+)-Ca2+ exchange in human epidermoid A 431 cells
Autor: M. L. Koenig, R. C. Smallridge, Juliann Gong Kiang
Publikováno v: The American journal of physiology. 263(1 Pt 1)
This study characterized cytosolic free Ca2+ concentration ([Ca2+]i) in normal and thermally injured human epidermoid A 431 cells. The resting [Ca2+]i in normal cells at 37 degrees C was 87 +/- 5 nM (n = 105). When cells were subjected to hyperthermi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e510cc21e07c3e3b0a5695f9b91e881f
https://pubmed.ncbi.nlm.nih.gov/1636682
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