Zobrazeno 1 - 10
of 32
pro vyhledávání: '"R. C. Pierce"'
Autor:
Yumiao Han, Lisa A. Briand, Adrian C. Arreola, Benjamin A. Garcia, Heath D. Schmidt, Mathieu E. Wimmer, Bruno Fant, Leonardo A. Guercio, R. C. Pierce, Simone Sidoli
Paternal environmental perturbations including exposure to drugs of abuse can produce profound effects on the physiology and behavior of offspring via epigenetic modifications. Here we show that adult drug-naive male offspring of cocaine-exposed sire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a22379f78b67a8b68441388e7a1350
https://europepmc.org/articles/PMC5568460/
https://europepmc.org/articles/PMC5568460/
Autor:
R. C. Pierce, Ghazaleh Sadri-Vakili, Gavin R. Sangrey, Shayna B. Darnell, Jang-Ho J. Cha, Heath D. Schmidt, Karen N. McFarland, Megan N. Huizenga
Publikováno v:
Molecular psychiatry
Activation of AMPA receptors in the nucleus accumbens is necessary for the reinstatement of cocaine-seeking behavior, an animal model of drug craving and relapse. AMPA receptors are tetrameric protein complexes that consist of GluA1-GluA4 subunits, o
Publikováno v:
European Journal of Neuroscience. 30:1358-1369
The direct glutamatergic projection from the medial prefrontal cortex (mPFC) to the nucleus accumbens plays a critical role in mediating the reinstatement of cocaine seeking behavior. The mPFC also sends glutamatergic projections to the pedunculopont
Autor:
M. E. Gerard, Katie R. Famous, Clifford M. Knapp, F. M. Vassoler, Conan Kornetsky, Heath D. Schmidt, R. C. Pierce, Domenic A. Ciraulo
Publikováno v:
The Journal of Neuroscience. 28:8735-8739
Increasing evidence suggests that deep brain stimulation (DBS), which is currently being used as a therapy for neurological diseases, may be effective in the treatment of psychiatric disorders as well. Here, we examined the influence of DBS of the nu
Autor:
David H. Farb, Ghazaleh Sadri-Vakili, R. C. Pierce, D. W. Johnson, Terrell T. Gibbs, G. C. Janis
Publikováno v:
Journal of Neurochemistry. 86:92-101
Our laboratory has previously shown that the synthetic neuroactive steroid 3α-hydroxy-5β-pregnan-20-one hemisuccinate (3α5βHS) is a negative modulator of NMDA receptors in vitro. Similarly, 3α5βHS exhibits rapid sedative, analgesic, anticonvuls
Autor:
M E Wimmer, L A Briand, B Fant, L A Guercio, A C Arreola, H D Schmidt, S Sidoli, Y Han, B A Garcia, R C Pierce
Publikováno v:
Molecular Psychiatry. 22:1653-1653
Autor:
Avin Veerakumar, Janette Boulden, R. C. Pierce, Sheryl G. Beck, Fair M. Vassoler, Olivier Berton, Julie Espallergues, Collin Challis
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(35)
Serotonin (5-HT) modulates neural responses to socioaffective cues and can bias approach or avoidance behavioral decisions, yet the cellular mechanisms underlying its contribution to the regulation of social experiences remain poorly understood. We h
The balance between GABA-mediated inhibitory and glutamate-mediated excitatory synaptic transmission represents a fundamental mechanism for controlling nervous system function, and modulators that can alter this balance may participate in the pathoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ced642abeeb334984e17e72ed1c40b
https://europepmc.org/articles/PMC2864155/
https://europepmc.org/articles/PMC2864155/
Autor:
R. C. Pierce, Heath D. Schmidt
Publikováno v:
Neuroscience. 142(2)
Activation of D1-like (D1, D5) or D2-like (D1, D3, D4) dopamine receptors in the nucleus accumbens shell is sufficient to reinstate cocaine-seeking behavior in rats. The goal of these experiments was to assess whether cooperative activation of D1-lik
Autor:
Ausaf A. Bari, R. C. Pierce
Publikováno v:
Neuroscience. 135(3)
Cocaine self-administration experiments were designed to assess the respective roles of D1-like and D2-like dopamine receptors in the ventral forebrain in cocaine reinforcement. D1-like or D2-like dopamine receptor antagonists were microinjected into