Zobrazeno 1 - 2
of 2
pro vyhledávání: '"R. C. M. van Rees"'
Autor:
I. F. Schene, I. P. Joore, J. H. L. Baijens, R. Stevelink, G. Kok, S. Shehata, E. F. Ilcken, E. C. M. Nieuwenhuis, D. P. Bolhuis, R. C. M. van Rees, S. A. Spelier, H. P. J. van der Doef, J. M. Beekman, R. H. J. Houwen, E. E. S. Nieuwenhuis, S. A. Fuchs
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
While prime editing is a promising technique, some genomic sites remain difficult to edit. Here the authors present fluoPEER, fluorescent prime editing and enrichment reporter, to rank the efficiency of pegRNAs and prime editor variants.
Externí odkaz:
https://doaj.org/article/ff29147a3c594221b358c3489445515b
Autor:
I F, Schene, I P, Joore, J H L, Baijens, R, Stevelink, G, Kok, S, Shehata, E F, Ilcken, E C M, Nieuwenhuis, D P, Bolhuis, R C M, van Rees, S A, Spelier, H P J, van der Doef, J M, Beekman, R H J, Houwen, E E S, Nieuwenhuis, S A, Fuchs
Publikováno v:
Nature communications. 13(1)
Prime editing is a versatile genome-editing technique that shows great promise for the generation and repair of patient mutations. However, some genomic sites are difficult to edit and optimal design of prime-editing tools remains elusive. Here we pr