Zobrazeno 1 - 10
of 10
pro vyhledávání: '"R. C. Klann"'
Autor:
Kenneth J. Cohen, C. A. Long, S. Karandish, Moody D. Wharam, Donald Small, Michael B. Kastan, Charles N. Paidas, A. D. Friedman, Wing Leung, J. M. Davis, Michael J. Borowitz, S. J. Noga, T. J. Moss, Curt I. Civin, Cindy L. Schwartz, J. D. McMannis, R. C. Klann, Allen R. Chen
Publikováno v:
Bone Marrow Transplantation. 22:971-979
Many poor-risk neuroblastomas and tumours of the Ewing's sarcoma family (ET) recur despite autologous transplants. Recurrence may be due to tumor cells contained in the BM harvests or PBSC harvests. The objectives of this prospective study were to: (
Autor:
N. J. Shaw, J. S. Bevan, R. C. Klann, A. T. Ricker, Adrian J. L. Clark, J. Toppari, K. Näntö-Salonen, A. Weber, R. D. Harvey
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 80:65-71
Familial glucocorticoid deficiency is an autosomal recessive syndrome of adrenal unresponsiveness to ACTH characterized by glucocorticoid deficiency, high plasma ACTH levels, and a normal renin-aldosterone axis. Defects of the ACTH receptor have been
Autor:
R. C. Klann
Publikováno v:
Journal of Clinical Endocrinology & Metabolism. 77:969-975
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 77:969-975
Mutations in the T3-binding domain of the thyroid hormone receptor gene c-erbA beta result in dominant negative proteins and thyroid hormone resistance syndromes. Variable clinical manifestations of resistance to thyroid hormones have been reported,
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 6(3)
Thyroid hormone resistance syndromes, which result from heterozygous mutations in the beta 1 thyroid hormone receptor gene, are sometimes associated with adult short stature, but more frequently with delayed bone age (BA). Primary fibroblasts from yo
Publikováno v:
Anticancer research. 12(3)
In light of the discouraging results obtained with conventional chemotherapy of human colon cancer using 5-fluorouracil, we examined the effects of cis-diamminedichloroplatinum (cisplatin) alone and combined with 3'-deoxy-3'-azidothymidine (AZT) on c
Publikováno v:
Cancer research. 52(5)
We have previously demonstrated that the chemopreventive agent dehydroepiandrosterone (DHEA) inhibits the isoprenylation of cellular proteins by depletion of endogenous mevalonate. We now report that treatment of HT-29 SF human colonic adenocarcinoma
Autor:
R. C. Klann, Ann C. Marchok
Publikováno v:
Cell Proliferation. 15:473-482
The effects of 3.3 times 10-7 M to 3.3 times 10-5 M all-trans-retinoic acid (vitamin-A acid) on the total cell population dynamics of 165 S, a keratinizing epithelial cell line from carcinogen-exposed rat trachea, were studied. During the first 6 day
Publikováno v:
Cancer research. 49(3)
Homologous and heterologous gap-junctional intercellular communication (IC) was characterized in a panel of cell lines derived from selected stages of SENCAR mouse skin carcinogenesis. This panel included a "carcinogen-altered" cell line, 3PC, obtain
Autor:
S M, Fischer, D W, Jasheway, R C, Klann, A P, Butler, K E, Patrick, J K, Baldwin, G S, Cameron
Publikováno v:
Cancer research. 49(23)
The activation of protein kinase C, induction of ornithine decarboxylase (ODC), and hyperplasia have been suggested to be linked, sequential processes resulting from phorbol ester application to mouse skin. However, evidence is presented indicating t