Zobrazeno 1 - 10
of 18
pro vyhledávání: '"R. C. Jongejan"'
Autor:
Johan C. de Jongste, Ivan L. Bonta, Theo Stijnen, K.F. Kerrebijn, Anthon R. Hulsmann, R. C. Jongejan, H Rolien C Raatgeep
Publikováno v:
American Review of Respiratory Disease. 147:1483-1486
In this study we evaluated the role of epithelial versus subepithelial peptidases in the responses of isolated peripheral and central human airways to VIP. Human airways were obtained at thoracotomies (n = 8) and studied in organ baths. Intact or epi
Autor:
Johan C. de Jongste, Ivan L. Bonta, Theo Stijnen, Rolien H C Raatgeep, R. C. Jongejan, K. F. Kerrebijn
Publikováno v:
European Journal of Pharmacology. 203:187-194
In asthmatics, both the continuous release of mast cell-derived inflammatory mediators and damage of the airway epithelium may be related to the degree of bronchial responsiveness. We therefore evaluated the effect of inflammatory mediators and mast
Autor:
Theo Stijnen, R. C. Raatgeep, R. C. Jongejan, J. C. De Jongste, Ivan L. Bonta, K. F. Kerrebijn
Publikováno v:
British Journal of Pharmacology. 102:931-937
1. We studied the effect of hyperosmolarity on human isolated airways because a better understanding of the effect of hyperosmolarity on the human airway wall may improve insight into the pathophysiology of hyperosmolarity-induced bronchoconstriction
Publikováno v:
American Review of Respiratory Disease. 143:553-560
In asthma a temporal association exists between the late allergic reaction (LAR), the influx of granulocytes into the airway wall, and an increase in bronchial responsiveness. We therefore tested the hypothesis that activated human granulocytes const
Publikováno v:
American Review of Respiratory Disease. 142:1129-1132
Several studies have suggested that in asthmatics the quantities of inflammatory mediators such as histamine, thromboxane A2 (TxA2), prostaglandin D2 (PGD2), prostaglandin F2 alpha (PGF2 alpha), and leukotriene C4 (LTC4) that are present in the airwa
Publikováno v:
Journal of Applied Physiology. 68:1568-1575
The effects of hypo- and hyperosmolarity on the function of isolated human airways were studied. Changes in osmolarity induced an increasing bronchoconstriction that was proportional to the magnitude of the change in osmolarity. Hypertonicity-induced
Publikováno v:
American Review of Respiratory Disease. 143:1194-1196
In asthma the dose-response curve to inhaled methacholine (MCh) is shifted leftwards and shows an increased slope and maximum. Two factors might contribute to the different form and position of this curve: (1) mediator-induced airway muscle hypersens
Autor:
A. Bon, R. C. Jongejan
Publikováno v:
Clinical Rheumatology. 20:2-3
The aim of this study was to evaluate whether dexibuprofen meets the basic requirements of Dutch General Practitioners (GPs) for acceptance as an analgesic in mild to moderate pain. The available GP treatment standards for mild to moderate pain were
Publikováno v:
Mediators in Airway Hyperreactivity ISBN: 9783034873819
The presence of low concentrations of histamine or the stable thromboxane analogue U46619 and the removal of the epithelium separately and addictively increase the sensitivity of isolated human airways to methacholine. This raises the possibility tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66d7935bdae63775e1c796dd946a8517
https://doi.org/10.1007/978-3-0348-7379-6_38
https://doi.org/10.1007/978-3-0348-7379-6_38
Publikováno v:
Agents and actions. Supplements. 31
Human granulocytes activated with serum treated zymosan (0.2 mg/ml) contract isolated human airways. The magnitude of the contraction depends on the number of granulocytes and the proportion of eosinophils among the granulocytes. The contraction is b