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Akademický článek

Development and Optimisation of Inhalable EGCG Nano-Liposomes as a Potential Treatment for Pulmonary Arterial Hypertension by Implementation of the Design of Experiments Approach

Autor: Fatma Haddad, Nura Mohammed, R. C. Gopalan, Yousef Al Ayoub, Md Talat Nasim, K. H. Assi

Publikováno v: Pharmaceutics, Vol 15, Iss 2, p 539 (2023)

Epigallocatechin gallate (EGCG), the main ingredient in green tea, holds promise as a potential treatment for pulmonary arterial hypertension (PAH). However, EGCG has many drawbacks, including stability issues, low bioavailability, and a short half-l

Externí odkaz: https://doaj.org/article/fc8bb34762cd48ea82a2b6486ec6dbab

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Association of a haplotype for tumor necrosis factor in siblings with late-onset Alzheimer disease: the NIMH Alzheimer Disease Genetics Initiative

Autor: J S, Collins, R T, Perry, B, Watson, L E, Harrell, R T, Acton, D, Blacker, M S, Albert, R E, Tanzi, S S, Bassett, M G, McInnis, R D, Campbell, R C, Go

Publikováno v: American journal of medical genetics. 96(6)

Tumor necrosis factor (TNF), a proinflammatory cytokine, may be involved in the pathogenesis of Alzheimer disease (AD) based on observations that senile plaques have been found to upregulate proinflammatory cytokines. Additionally, nonsteroidal anti-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::064c3bffcf3c4ae05d5de164042f7c4b
https://pubmed.ncbi.nlm.nih.gov/11121190

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Susceptibility locus for IgA deficiency and common variable immunodeficiency in the HLA-DR3, -B8, -A1 haplotypes

Autor: H W, Schroeder, Z B, Zhu, R E, March, R D, Campbell, S M, Berney, S A, Nedospasov, R L, Turetskaya, T P, Atkinson, R C, Go, M D, Cooper, J E, Volanakis

Publikováno v: Molecular medicine (Cambridge, Mass.). 4(2)

BACKGROUND: A common genetic basis for IgA deficiency (IgAD) and common variable immunodeficiency (CVID) is suggested by their occurrence in members of the same family and the similarity of the underlying B cell differentiation defects. An associatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b25506a15c3ac8ffedd1370343e6ae29
https://pubmed.ncbi.nlm.nih.gov/9508785

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Instability of the FMR2 trinucleotide repeat region associated with expanded FMR1 alleles

Autor: T C, Brown, J C, Tarleton, R C, Go, J W, Longshore, M, Descartes

Publikováno v: American journal of medical genetics. 73(4)

The fragile sites FRAXA and FRAXE, located approximately 600 kb apart on Xq27.3 and Xq28, respectively, are due to a CGG trinucleotide repeat expansion. Although the expansion mechanism for these and other trinucleotide repeat disorders remains unkno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6f5cb24e734499ecc211723e2394405a
https://pubmed.ncbi.nlm.nih.gov/9415473

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Disease classification and transmission effects on linkage analyses in the NIMH1 bipolar disorder pedigrees

Autor: J S, Collins, R C, Go

Publikováno v: Genetic epidemiology. 14(6)

In this analysis of bipolar affective disorder, 22 families from the NIMH1 data set were further grouped into three transmission patterns: male to male, male to female, and maternal. The data were analyzed under three classifications of affection sta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8df84a85c734f5172a6b17e1e999e448
https://pubmed.ncbi.nlm.nih.gov/9433547

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Genetic epidemiologic methods to screen for matrilineal inheritance in mitochondrial disorders

Autor: F, Mili, W D, Flanders, S L, Sherman, R C, Go, D C, Wallace

Publikováno v: Genetic epidemiology. 13(6)

We propose a method to screen for the matrilineal inheritance in mitochondrial disorders by comparing the risk of disease in a person whose mother is affected or whose maternal grandmother or aunt or uncle is affected to the risk of disease in a pers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e28c71f2062f9b37a2d1105d791a0906
https://pubmed.ncbi.nlm.nih.gov/8968717

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Sexual differences in lipoprotein composition in a family with dyslipidemic hypertension with premature atheroschlerosis: deficiency of high-density lipoprotein-L and high-density lipoprotein-M 'apolipoprotein-I alone' particle

Autor: T A, Hughes, M A, Moore, M, Joyce, R C, Go, J P, Segrest, T, Blackwell

Publikováno v: The Journal of laboratory and clinical medicine. 119(1)

This article describes a family with a high incidence of premature atherosclerosis and primary hypertriglyceridemia in the women. The lipoprotein composition of this family was investigated with a new methodology that combines gradient ultracentrifug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::396c9e89f6329d0e0d7229bff7a279cd
https://pubmed.ncbi.nlm.nih.gov/1727908

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Akademický článek

Closing a gap in tropical forest biomass estimation: taking crown mass variation into account in pantropical allometries

Publikováno v: Biogeosciences, Vol 13, Iss 5, Pp 1571-1585 (2016)

Accurately monitoring tropical forest carbon stocks is a challenge that remains outstanding. Allometric models that consider tree diameter, height and wood density as predictors are currently used in most tropical forest carbon studies. In particular

Externí odkaz: https://doaj.org/article/a64c82e04bc34a02a47dbd41f09343e1

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