Zobrazeno 1 - 7
of 7
pro vyhledávání: '"R. C. Garrad"'
Autor:
L I, Santiago-Pérez, R V, Flores, C, Santos-Berríos, N E, Chorna, B, Krugh, R C, Garrad, L, Erb, G A, Weisman, F A, González
Publikováno v:
Journal of cellular physiology. 187(2)
Activation of P2Y(2) receptors by extracellular nucleotides has been shown to induce phenotypic differentiation of human promonocytic U937 cells that is associated with the inflammatory response. The P2Y(2) receptor agonist, UTP, induced the phosphor
Publikováno v:
Molecular and cellular biochemistry. 206(1-2)
The equal potency and efficacy of the agonists, ATP and UTP, pharmacologically distinguish the P2Y2 receptor from other nucleotide receptors. Investigation of the desensitization of the P2Y2 receptors is complicated by the simultaneous expression of
Autor:
M, Otero, R C, Garrad, B, Velázquez, M G, Hernández-Pérez, J M, Camden, L, Erb, L L, Clarke, J T, Turner, G A, Weisman, F A, González
Publikováno v:
Molecular and cellular biochemistry. 205(1-2)
UTP activates P2Y, receptors in both 1321N1 cell transfectants expressing the P2Y2 receptor and human HT-29 epithelial cells expressing endogenous P2Y, receptors with an EC50 of 0.2-1.0 microM. Pretreatment of these cells with UTP diminished the effe
Publikováno v:
Progress in brain research. 120
Autor:
R C, Garrad, M A, Otero, L, Erb, P M, Theiss, L L, Clarke, F A, Gonzalez, J T, Turner, G A, Weisman
Publikováno v:
The Journal of biological chemistry. 273(45)
Molecular determinants of P2Y2 receptor desensitization and sequestration have been investigated. Wild-type P2Y2 receptors and a series of five C-terminal truncation mutants of the receptor were epitope-tagged and stably expressed in 1321N1 cells. Th
Publikováno v:
Advances in experimental medicine and biology. 431
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461374565
Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane-conductance regulator (CFTR), a cAMP-dependent chloride transporter expressed in epithelial tissue. A novel treatment being developed for CF utilizes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd93ff7c6e96fbf8bd3c84ec84b75fd3
https://doi.org/10.1007/978-1-4615-5381-6_82
https://doi.org/10.1007/978-1-4615-5381-6_82