Zobrazeno 1 - 10
of 13
pro vyhledávání: '"R. C. Glen"'
Autor:
C. J. Harris, C. Heide, R. C. Glen, P. M. Doyle, G. E. Tranter, P. N. Sanderson, B. D. Hudson, A. W. R. Payne
Publikováno v:
International Journal of Peptide and Protein Research. 43:588-596
The solution conformation of a cyclic RGD peptide analogue, cyclo-(S,S)-2-merrcaptobenzoate-arginine-glycine-aspartate -2-mercaptoanilide, has been determined via two independent approaches for the searching of conformational space and identification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2621378ce54f53a81a7511727c8a6f
https://doi.org/10.1111/j.1399-3011.1994.tb00561.x
https://doi.org/10.1111/j.1399-3011.1994.tb00561.x
Publikováno v:
Spectroscopy Letters. 31:269-274
The 13C NMR spectra of a series of N-acyl six-member ring nitrogen heterocycles have been measured as a function of temperature and the results interpreted in terms of restricted amide rotation and ring inversion. Slow rotation is observed on the NMR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e41765689fb56023fc11a260d81784aa
https://doi.org/10.1080/00387019808003251
https://doi.org/10.1080/00387019808003251
Autor:
C. R. Beddell, Jeremy K. Nicholson, John C. Lindon, Ian D. Wilson, V. S. Rose, R.J. Ruane, R. C. Glen, P. Davis, Belinda C. Cupid
Publikováno v:
Chromatographia. 37:241-249
The use of theoretically calculated molecular properties as predictors for retention in reversed-phase HPLC has been explored. HPLC retention times have been measured for a series of 47 substituted aromatic molecules in three solvent mixtures and ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8990047b31d5553712a3a7cdb1d99a3d
https://doi.org/10.1007/bf02278628
https://doi.org/10.1007/bf02278628
Publikováno v:
Spectroscopy Letters. 26:745-749
The 13C NMR spectrum of N-formylmorpholine has been interpreted in terms of conformational flexibilty. In contrast to conclusions from a previous study, the formyl group shows slow rotation at 303K, with coalescence measurements indicating a barrier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::004d79dea642eef167bd333e70a04cf1
https://doi.org/10.1080/00387019308011567
https://doi.org/10.1080/00387019308011567
Autor:
A, Bender, S, Fergus, W R J D, Galloway, F G, Glansdorp, D M, Marsden, R L, Nicholson, R J, Spandl, G L, Thomas, E E, Wyatt, R C, Glen, D R, Spring
Publikováno v:
Ernst Schering Research Foundation workshop. (58)
This article covers the diversity-oriented synthesis (DOS) of small molecules in order to generate a collection of pure compounds that are attractive for lead generation in a phenotypic, high-throughput screening approach useful for chemical genetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e68d47fdb90e57ab57d11c5a46a9cd3
https://pubmed.ncbi.nlm.nih.gov/16708998
https://pubmed.ncbi.nlm.nih.gov/16708998
Publikováno v:
Journal of molecular biology. 267(3)
Prediction of small molecule binding modes to macromolecules of known three-dimensional structure is a problem of paramount importance in rational drug design (the "docking" problem). We report the development and validation of the program GOLD (Gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dba1fe1d853254f5bee39c7fba65f028
https://pubmed.ncbi.nlm.nih.gov/9126849
https://pubmed.ncbi.nlm.nih.gov/9126849
Publikováno v:
Heart. 96:e23-e23
The recently discovered apelin family of peptides mediate their actions by a single G-protein coupled receptor, APJ. We have previously shown that apelins have three major actions in the human cardiovascular system: endothelium-dependent vasodilatati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e034907103f6106c52a255fa77961065
https://doi.org/10.1136/hrt.2010.205781.48
https://doi.org/10.1136/hrt.2010.205781.48
Autor:
F Y, Ghauri, C A, Blackledge, R C, Glen, B C, Sweatman, J C, Lindon, C R, Beddell, I D, Wilson, J K, Nicholson
Publikováno v:
Biochemical pharmacology. 44(10)
An extensive set of computed molecular properties, both steric and electronic, have been calculated using molecular orbital and empirical methods for benzoic acid (1) and a congeneric series of substituted benzoic acids, i.e. 2-, 3- and 4-fluorobenzo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5010ffb4aafa904ef9bdd3add7502c6d
https://pubmed.ncbi.nlm.nih.gov/1449513
https://pubmed.ncbi.nlm.nih.gov/1449513
Publikováno v:
Journal of Chemical Information & Modeling; Jan2009, Vol. 49 Issue 1, p1-5, 5p
Autor:
J.C. Lunn, G. Kuhnle, V. Mai, C. Frankenfeld, D.E.G. Shuker, R. C. Glen, J.M. Goodman, J.R.A. Pollock, S.A. Bingham
Publikováno v:
Carcinogenesis; Mar2007, Vol. 28 Issue 3, p685-690, 6p