Zobrazeno 1 - 10
of 20
pro vyhledávání: '"R. Bridget Ferns"'
Autor:
Eloise Busby, Alexandra S. Whale, R. Bridget Ferns, Paul R. Grant, Gary Morley, Jonathan Campbell, Carole A. Foy, Eleni Nastouli, Jim F. Huggett, Jeremy A. Garson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abtract Establishing a cure for HIV is hindered by the persistence of latently infected cells which constitute the viral reservoir. Real-time qPCR, used for quantification of this reservoir by measuring HIV DNA, requires external calibration; a commo
Externí odkaz:
https://doaj.org/article/2b436614675045baa96789477b129f7b
Autor:
Gonzalo Yebra, Dan Frampton, Tiziano Gallo Cassarino, Jade Raffle, Jonathan Hubb, R Bridget Ferns, Laura Waters, C Y William Tong, Zisis Kozlakidis, Andrew Hayward, Paul Kellam, Deenan Pillay, Duncan Clark, Eleni Nastouli, Andrew J Leigh Brown, ICONIC Consortium
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192081 (2018)
The ICONIC project has developed an automated high-throughput pipeline to generate HIV nearly full-length genomes (NFLG, i.e. from gag to nef) from next-generation sequencing (NGS) data. The pipeline was applied to 420 HIV samples collected at Univer
Externí odkaz:
https://doaj.org/article/a9f75c90552b4a0c8f70a86dbdd1233b
Autor:
Eleanor R. Gray, Jeremy A. Garson, Patrícia Carvalho de Sequeira, R. Bridget Ferns, Judith Heaney, Eleni Nastouli
Publikováno v:
Journal of Virological Methods
Dengue is a vector-transmitted viral infection that is a significant cause of morbidity and mortality in humans worldwide, with over 50 million apparent cases and a fatality rate of 2.5 % of 0.5 million severe cases per annum in recent years. Four se
Autor:
Catherine F, Houlihan, Dan, Frampton, R Bridget, Ferns, Jade, Raffle, Paul, Grant, Myriam, Reidy, Leila, Hail, Kirsty, Thomson, Frank, Mattes, Zisis, Kozlakidis, Deenan, Pillay, Andrew, Hayward, Eleni, Nastouli
Publikováno v:
The Journal of Infectious Diseases
Traditional epidemiological investigation of nosocomial transmission of influenza involves the identification of patients who have the same influenza virus type and who have overlapped in time and place. This method may misidentify transmission where
Autor:
Eleanor R, Gray, Valérian, Turbé, Victoria E, Lawson, Robin H, Page, Zara C, Cook, R Bridget, Ferns, Eleni, Nastouli, Deenan, Pillay, Hiromi, Yatsuda, Dale, Athey, Rachel A, McKendry
Publikováno v:
NPJ Digital Medicine
Despite widened access to HIV testing, around half of those infected worldwide are unaware of their HIV-positive status and linkage to care remains a major challenge. Current rapid HIV tests are typically analogue risking incorrect interpretation, no
Autor:
Gonzalo, Yebra, Dan, Frampton, Tiziano, Gallo Cassarino, Jade, Raffle, Jonathan, Hubb, R Bridget, Ferns, Laura, Waters, C Y William, Tong, Zisis, Kozlakidis, Andrew, Hayward, Paul, Kellam, Deenan, Pillay, Duncan, Clark, Eleni, Nastouli, Andrew J, Leigh Brown
Publikováno v:
PLoS ONE
Background & methods The ICONIC project has developed an automated high-throughput pipeline to generate HIV nearly full-length genomes (NFLG, i.e. from gag to nef) from next-generation sequencing (NGS) data. The pipeline was applied to 420 HIV sample
Autor:
Alasdair C. Steven, Stephen J. Stahl, Paul T. Wingfield, Audray K. Harris, Joe G. Vethanayagam, Norman R. Watts, Richard S. Tedder, R. Bridget Ferns
Publikováno v:
Journal of Molecular Biology. 398:530-541
The hepatitis B virus core gene codes for two closely related antigens: a 21-kDa protein that forms dimers that assemble as multimegadalton capsids, and a 17-kDa protein that also forms dimers but that do not assemble. The proteins, respectively refe
Publikováno v:
Journal of Clinical Virology. 39:199-204
Background: In patients with chronic hepatitis B virus (HBV) infection DNA levels do not always fall after anti-hepatitis B e (anti-HBe) seroconversion. Objectives: To follow longitudinally through HB e antigen (HBeAg) loss HBV DNA levels and core pr
Autor:
Richard Gilson, Eleni Nastouli, Alexander W. Tarr, R. Bridget Ferns, Stéphane Hué, Jonathan K. Ball, Deenan Pillay, Richard A. Urbanowicz, Jeremy A. Garson, C. Patrick McClure
Publikováno v:
Virology. 492
HIV-1 infected patients who acquire HCV infection have higher rates of chronicity and liver disease progression than patients with HCV mono-infection. Understanding early events in this pathogenic process is important. We applied single genome sequen
Autor:
Adele L. McCormick, R. Bridget Ferns, Eleni Nastouli, Daniel P. Webster, Sanjay Bhagani, Laura Waters, Emily Chung, Paul R. Grant, Roberto Rigatti, Miao He
Publikováno v:
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 70
The current epidemic of Hepatitis C infection in HIV-positive men who have sex with men is associated with increasing use of recreational drugs. Multiple HCV infections have been reported in haemophiliacs and intravenous drug users. Using ultra-deep