Zobrazeno 1 - 10
of 570
pro vyhledávání: '"R. Brüggemann"'
Autor:
Thayse R. Brüggemann, Troy Carlo, Nandini Krishnamoorthy, Melody G. Duvall, Raja-Elie E. Abdulnour, Julie Nijmeh, Hong Yong Peh, Harilaos Filippakis, Roxanne H. Croze, Byoungsook Goh, Sungwhan F. Oh, Bruce D. Levy
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105185- (2022)
Summary: Lipid phosphate phosphatases are a family of enzymes with diverse cellular metabolic functions. Phospholipid phosphatase 6 (PLPP6) is a regulator of cellular polyisoprenyl phosphates; however, its in vivo functions remain to be determined. H
Externí odkaz:
https://doaj.org/article/dba573f5d9f9430aac6578dbdef405d5
Autor:
Luciana P. Tavares, Thayse R. Brüggemann, Rafael M. Rezende, Marina G. Machado, R. Elaine Cagnina, Ashley E. Shay, Cristiana C. Garcia, Julie Nijmeh, Mauro M. Teixeira, Bruce D. Levy
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Influenza A virus (IAV) infections are a leading cause of mortality worldwide. Excess mortality during IAV epidemics and pandemics is attributable to secondary bacterial infections, particularly pneumonia caused by Streptococcus pneumoniae.
Externí odkaz:
https://doaj.org/article/3a864d6cb7fe4807bf4973222976c38d
Autor:
Katherine H. Walker, Nandini Krishnamoorthy, Thayse R. Brüggemann, Ashley E. Shay, Charles N. Serhan, Bruce D. Levy
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Viral pneumonias are a major cause of morbidity and mortality, owing in part to dysregulated excessive lung inflammation, and therapies to modulate host responses to viral lung injury are urgently needed. Protectin conjugates in tissue regeneration 1
Externí odkaz:
https://doaj.org/article/9375ae0da5bd41c392dc0477946984d8
Autor:
Nandini Krishnamoorthy, Katherine H. Walker, Thayse R. Brüggemann, Luciana P. Tavares, Ethan W. Smith, Julie Nijmeh, Yan Bai, Xingbin Ai, R. Elaine Cagnina, Melody G. Duvall, Jessica A. Lehoczky, Bruce D. Levy
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The resolution of infection is an active process with specific molecular and cellular mechanisms that temper inflammation and enhance pathogen clearance. Here, the specialized pro-resolving mediator (SPM) Maresin 1 (MaR1) inhibited respiratory syncyt
Publikováno v:
Journal of materials science / Materials in electronics 31(5), 3960-3975 (2020). doi:10.1007/s10854-020-02944-4
Reversible and irreversible changes due to long term air and short term de-ionized water (DIW) or pure oxygen exposure were investigated in about 1 mu m thick hydrogenated microcrystalline silicon (mu c-Si:H) films deposited on rough glass substrates
Akademický článek
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Autor:
Pier Giorgio, Puzzovio, Thayse R, Brüggemann, Hadas, Pahima, David, Mankuta, Bruce D, Levy, Francesca, Levi-Schaffer
Publikováno v:
Pharmacological Research. 178:106172
Cromolyn Sodium (CS) has been used in the past as an anti-allergy drug owing to its mast cell (MC) stabilizing properties that impair histamine release. However, additional mechanisms for its clinical actions are likely and might help to identify new
Akademický článek
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Akademický článek
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Autor:
Nandini, Krishnamoorthy, David N, Douda, Thayse R, Brüggemann, Isabell, Ricklefs, Melody G, Duvall, Raja-Elie E, Abdulnour, Kimberly, Martinod, Luciana, Tavares, Xiao, Wang, Manuela, Cernadas, Elliot, Israel, David T, Mauger, Eugene R, Bleecker, Mario, Castro, Serpil C, Erzurum, Benjamin M, Gaston, Nizar N, Jarjour, Sally, Wenzel, Eleanor, Dunican, John V, Fahy, Daniel, Irimia, Denisa D, Wagner, Bruce D, Levy
Publikováno v:
Science immunology. 3(26)
Severe asthma is a debilitating and treatment refractory disease. As many as half of these patients have complex neutrophil-predominant lung inflammation that is distinct from milder asthma with type 2 eosinophilic inflammation. New insights into sev