Zobrazeno 1 - 10
of 91
pro vyhledávání: '"R. Bonnafous"'
Autor:
J Tisne-Versailles, G. Tchani, R Bonnafous, S Younes, Genevieve Baziard-Mouysset, Marc Payard, Jean-Luc Stigliani
Publikováno v:
European Journal of Medicinal Chemistry. 29:87-93
Twenty-three new phosphonic ester derivatives of stilbene exhibiting structural analogies with fostedil are described. Examination of calcium antagonism showed that this activity could not be increased by introducing electron-withdrawing, electron-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aed40147a379c6c086ddf82186b8d82a
https://doi.org/10.1016/0223-5234(94)90204-6
https://doi.org/10.1016/0223-5234(94)90204-6
Publikováno v:
Pharmaceutica Acta Helvetiae. 68:173-179
Four aryl vinyl diethyl benzylphosphonates related to Fostedil were synthesized and evaluated for their in vitro calcium-inhibitory activity. None of these compounds exhibited any calcium antagonistic profile. Unlike a series of diethyl-styryl benzyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6967c593c03c488285c96ea523f1a943
https://doi.org/10.1016/0031-6865(94)90040-x
https://doi.org/10.1016/0031-6865(94)90040-x
Autor:
G Baziard-Mouysset, J Tisne-Versailles, Jean-Luc Stigliani, S Younes, R Bonnafous, G de Saqui-Sannes, M. Payard
Publikováno v:
European Journal of Medicinal Chemistry. 28:943-948
Several phosphonic diethyl esters were synthesized and their calcium antagonistic activity evaluated in vitro. The diethyl phosphonate group was condensed on substituted [diphenylmethyl], [(2-benzofuranyl)phenylmethyl], [(4-(diphenylmethyl-1-piperazi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5725df3300d1b07ff59e9987f52b714c
https://doi.org/10.1016/0223-5234(93)90049-k
https://doi.org/10.1016/0223-5234(93)90049-k
Autor:
A. Marty, A. M. Bessac, J. Tisne-Versailles, J. P. Rieu, J. F. Patoiseau, D. C. H. Bigg, A. Duflos, R. Bonnafous, Y. Verscheure, J. C. Tristani
Publikováno v:
European Journal of Medicinal Chemistry. 28:683-691
A series of 2,3-dihydro-4 H -1,3-benzoxazin-4-ones substituted at the 3-position with an arylalkyaminoalkyl group have been synthesized and their specific bradycardic and antiarrythmic activities evaluated. Bradycardia is optimal when the aromatic ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4daf631260569b86987f8f27e0708c89
https://doi.org/10.1016/0223-5234(93)90027-c
https://doi.org/10.1016/0223-5234(93)90027-c
Autor:
R Bonnafous, Jean-Luc Stigliani, G Baziard-Mouysset, G. Tchani, J Tisne-Versailles, M. Payard
Publikováno v:
European Journal of Medicinal Chemistry. 28:539-546
In this work we present about 15 original heterocyclic diethyl benzylphosphonate analogues of fostedil, in which we have varied the nature of the heterocycle, the substituents or the phosphonic group, or even the position of this latter. Three diethy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b49e95cb4af1d88bedd571d7f6db2a9f
https://doi.org/10.1016/0223-5234(93)90084-r
https://doi.org/10.1016/0223-5234(93)90084-r
Autor:
J. Bellan, C. Bories, Philippe M. Loiseau, J Tisne-Versailles, P. Gayral, G Baziard-Mouysset, A. Rached, R Bonnafous, M. Payard
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a58e2c0b6e32886c701feae1bf8e0e2
https://doi.org/10.1002/chin.199244199
https://doi.org/10.1002/chin.199244199
Autor:
J. F. Patoiseau, D. C. H. Bigg, A. Duflos, J. C. Tristani, R. Bonnafous, J. P. Rieu, A. M. Bessac, A. Marty, Y. Verscheure, J. Tisne-Versailles
Publikováno v:
ChemInform. 25
A series of 2,3-dihydro-4 H -1,3-benzoxazin-4-ones substituted at the 3-position with an arylalkyaminoalkyl group have been synthesized and their specific bradycardic and antiarrythmic activities evaluated. Bradycardia is optimal when the aromatic ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb3f5598deb5f675f9ae83b374c07743
https://doi.org/10.1002/chin.199404190
https://doi.org/10.1002/chin.199404190
Autor:
J. Bellan, J Tisne-Versailles, Jean-Luc Stigliani, R Bonnafous, M. Payard, G Baziard-Mouysset, G. Grassy, G. Tchani, S Younes
Publikováno v:
European Journal of Medicinal Chemistry. 27:845-850
Resume Les proprietes inhibitrices calciques d'une serie de 39 benzylphosphonates de diethyle diversement substitues, analogues du Fostedil, ont eteevaluees. Seuls 6 composes presentent une certaine activite, celle-ci reste cependant beaucoup plus fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66acc8248c972b3f8e10f3905cf74f85
https://doi.org/10.1016/0223-5234(92)90120-p
https://doi.org/10.1016/0223-5234(92)90120-p
Autor:
R. Bonnafous, Françoise Fichaux
Publikováno v:
Pancreas. 7:585-594
Non-insulin-dependent diabetes was obtained in rabbits following pancreatic duct ligation. The insulin responses to D-glucose and to L-arginine were studied in the isolated perfused pancreas of control, prediabetic, and diabetic rabbits. In controls,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072f7fa62ba3ea327b83ad0cd2bd9000
https://doi.org/10.1097/00006676-199209000-00012
https://doi.org/10.1097/00006676-199209000-00012
Autor:
Christian Bories, Philippe Gayral, J. Bellan, R Bonnafous, G Baziard-Mouysset, J Tisne-Versailles, Philippe M. Loiseau, A. Rached, M. Payard
Publikováno v:
European Journal of Medicinal Chemistry. 27:425-429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42b5533371a05527733f2fde583cef8c
https://doi.org/10.1016/0223-5234(92)90158-w
https://doi.org/10.1016/0223-5234(92)90158-w