Zobrazeno 1 - 10
of 4 707
pro vyhledávání: '"R. Blake"'
Autor:
Ethan C. Veit, Madihah S. Salim, Mariel J. Jung, R. Blake Richardson, Ian N. Boys, Meghan Quinlan, Erika A. Barrall, Eva Bednarski, Rachael E. Hamilton, Caroline Kikawa, Nels C. Elde, Adolfo García-Sastre, Matthew J. Evans
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Zika and dengue virus nonstructural protein 5 antagonism of STAT2, a critical interferon signaling transcription factor, to suppress the host interferon response is required for viremia and pathogenesis in a vertebrate host. This affects vir
Externí odkaz:
https://doaj.org/article/c1492f081af343ca9b56c04dbdd379b3
Autor:
R. Blake Billmyre
Publikováno v:
mSphere, Vol 9, Iss 10 (2024)
ABSTRACT Blake Billmyre uses functional genomics to help understand the biology of fungal pathogens, with an emphasis on evolution of virulence relevant traits and drug resistance. In this mSphere of Influence article, he reflects on how two papers (
Externí odkaz:
https://doaj.org/article/d08225b2374b48388f7100022d6d6f77
Autor:
Christopher B. Theriault, Tracy Burns, Kenneth Goldschneider, Anjali Koka, Deirdre Logan, Steven J. Weisman, Robert T. Wilder, R. Blake Windsor, William T. Zempsky
Publikováno v:
Frontiers in Pain Research, Vol 5 (2024)
IntroductionMany youth with pain lack access to pediatric pain expertise. There is a critical shortage of pediatric pain physicians, due partly to a paucity of training programs in Pediatric Pain Medicine. Pain fellowships are Anesthesiology-based an
Externí odkaz:
https://doaj.org/article/f493edf6241c4fdb9f08d0a6e8ab457e
Autor:
Yara Bilen, MD, Jesse D. Schold, PhD, Susana Arrigain, MA, R. Blake Buchalter, PhD, Anne M. Huml, MD
Publikováno v:
Transplantation Direct, Vol 10, Iss 1, p e1559 (2024)
Background. Living kidney transplant is the most effective renal replacement therapy for patients with end-stage kidney disease. Community-level factors contribute to pervasive socioeconomic and racial disparities in access to living donor kidney tra
Externí odkaz:
https://doaj.org/article/7c4182523189476f8424d89886c1d9fd
Publikováno v:
Land, Vol 12, Iss 12, p 2168 (2023)
As the global population rises, there is an ever-increasing demand for food, in terms of volume, quality and sustainable production. Protected Cropping Structures (PCS) provide controlled farming environments that support the optimum use of crop inpu
Externí odkaz:
https://doaj.org/article/bd07ddbebff047ec9e0dfb5e1c548512
Publikováno v:
The Lancet Regional Health. Americas, Vol 18, Iss , Pp 100415- (2023)
Summary: Background: Appalachia is rural and socioeconomically deprived with a heavy burden of neurological disorders and poor access to healthcare providers. Rates of neurological disorders are increasing over time without equal increases in provide
Externí odkaz:
https://doaj.org/article/fde44a7479e34d558b609e3ff8d827b2
Autor:
R. Blake Billmyre
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Over the past decade, Candida auris has emerged as a highly transmissible human fungal pathogen. Because of its ability to transmit between patients in hospitals and its ability to rapidly develop drug resistance, C. auris presents unique ch
Externí odkaz:
https://doaj.org/article/0fc3d60e7dda4d8da7f51dd08351a986
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
The authors show that resistance to the antifungal 5-fluorocytosine in Cryptococcus deuterogattii is acquired more frequently in isolates with elevated mutation rate, and is associated with alterations in capsule biosynthesis and nucleotide metabolis
Externí odkaz:
https://doaj.org/article/f7fc4a07b3e44f9382953de7b6a59040
Autor:
Mahmoud AbuEid, Donna M. McAllister, Laura McOlash, Megan Cleland Harwig, Gang Cheng, Donovan Drouillard, Kathleen A. Boyle, Micael Hardy, Jacek Zielonka, Bryon D. Johnson, R. Blake Hill, Balaraman Kalyanaraman, Michael B. Dwinell
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102653- (2021)
Summary: Metabolic heterogeneity within the tumor microenvironment promotes cancer cell growth and immune suppression. We determined the impact of mitochondria-targeted complex I inhibitors (Mito-CI) in melanoma. Mito-CI decreased mitochondria comple
Externí odkaz:
https://doaj.org/article/3630e5359dc747fea35d724c0b59cc72
Autor:
Andreas Weihofen, YuTing Liu, Joseph W. Arndt, Christian Huy, Chao Quan, Benjamin A. Smith, Jean-Luc Baeriswyl, Nicole Cavegn, Luzia Senn, Lihe Su, Galina Marsh, Pavan K. Auluck, Fabio Montrasio, Roger M. Nitsch, Warren D. Hirst, Jesse M. Cedarbaum, R. Blake Pepinsky, Jan Grimm, Paul H. Weinreb
Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 276-288 (2019)
Aggregation of α-synuclein (α-syn) is neuropathologically and genetically linked to Parkinson's disease (PD). Since stereotypic cell-to-cell spreading of α-syn pathology is believed to contribute to disease progression, immunotherapy with antibodi
Externí odkaz:
https://doaj.org/article/9c312d730f4444538aa0bb5f11e8cda5