Zobrazeno 1 - 10
of 293
pro vyhledávání: '"R. Bachur"'
Publikováno v:
Revista de la Facultad de Odontología. 30:15-19
Autor:
A. Weissman, S. Motov, L. Ryan, S. Halabi, C. Arias, A. Klein, S. Kaplan, R. Bachur, A. Study, R. Rothman
Publikováno v:
Annals of Emergency Medicine. 78:S49
Publikováno v:
Revista de la Facultad de Odontología. 30:1-2
Publikováno v:
Cancer Chemotherapy and Pharmacology. 42:447-453
CI-958, a new DNA-intercalating drug derived from a series of substituted 2H-[1] benzothiopyrano[4,3,2-cd ]indazoles, is being tested in clinical trails because of its curative properties against murine solid tumor models and because it has demonstra
Autor:
Linda H. Malkas, Merrill J. Egorin, Lapman Lun, Nicholas R. Bachur, Charles M. Trubey, Pei Ming Sun, Robert J. Hickey, E.Elizabeth Elliott
Publikováno v:
Biochemical Pharmacology. 55:1025-1034
We previously showed that anthracycline antibiotics potently block SV40 large T antigen helicase; in the present study, we describe the kinetics and the structure-activity characteristics of this process. The concentration vs effect data for helicase
Publikováno v:
Anti-cancer drug design. 14(1)
Certain DNA minor groove binding agents, distamycin, netropsin, and a series of anticancer bis-benzimidazoles can block DNA helicase activity by binding to duplex DNA at specific base sequences. DNA helicases are crucial to cell DNA replication, tran
Publikováno v:
Pediatrics. 97(6 Pt 1)
Publikováno v:
ACS Symposium Series ISBN: 9780841230408
Anthracycline Antibiotics: New Analogues, Methods of Delivery, and Mechanisms of Action
Anthracycline Antibiotics: New Analogues, Methods of Delivery, and Mechanisms of Action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e3b0093284cb55f2615dc8b75224d0a
https://doi.org/10.1021/bk-1995-0574.ch013
https://doi.org/10.1021/bk-1995-0574.ch013
Publikováno v:
Molecular pharmacology. 44(5)
DNA-binding antibiotics such as intercalators, narrow groove binders, and other substances modify duplex DNA, making it an altered substrate for DNA helicases. The intercalators daunorubicin, actinomycin D, echinomycin, and elsamicin, the narrow groo