Zobrazeno 1 - 10 of 37 pro vyhledávání: '"R. B. SYKES"'
1
A New Cephalosporin with a Dual Mode of Action
Autor: Susan E. Staniforth, R. B. Sykes, Cynthia H. O'Callaghan
Publikováno v: Antimicrobial Agents and Chemotherapy. 10:245-248
A cephalosporin, (6R,7R)-7-[(2R)-2-hydroxy-2-phenylacetamido]-3-(pyrid-2-yl- N -oxide) thiomethylceph-3-em-4-carboxylic acid (MCO), that could lead to a novel approach to the problem of β-lactamase destruction is described. The compound is slightly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ffb7b60211283099e24bd6d9159747
https://doi.org/10.1128/aac.10.2.245
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2
G7063-2, a new nitrogen-containing antibiotic of the epoxydon group, isolated from the fermentation broth of a species of Streptomyces
Autor: R. B. Sykes, Mary Noble, D. Noble
Publikováno v: The Journal of Antibiotics. 30:455-459
Antibiotic G7063-2, isolated from a Streptomyces species, is a new nitrogen-containing analogue of phyllostine and terreic acid. In vitro G7063-2 is moderately active against both Gram-positive and Gram-negative bacteria and weakly active against fun
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b7f969af9890d5eb92618edd46b3e4
https://doi.org/10.7164/antibiotics.30.455
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3
Cefuroxime - A new cephalosporin antibiotic
Autor: R. B. Sykes, D. M. Ryan, P. W. Muggleton, Cynthia H. O'callaghan, R. D. Foord
Publikováno v: The Journal of Antibiotics. 29:29-37
Cefuroxime is a new broad spectrum cephalosporin antibiotic for administration by injection. It is stable to most beta-lactamases. It is active against gram-positive organisms, including penicillinase-producing staphylococci, and has wide activity ag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a129694f6047055acf51515b4016dfb1
https://doi.org/10.7164/antibiotics.29.29
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4
Biosynthesis of monobactam compounds: origin of the carbon atoms in the beta-lactam ring
Autor: J O'Sullivan, R B Sykes, C A Aklonis, A M Gillum, M L Souser
Publikováno v: Antimicrobial Agents and Chemotherapy. 21:558-564
The biosynthesis of monobactams by strains of Chromobacterium violaceum, Acetobacter sp., and Agrobacterium radiobacter was studied. Monobactams were produced during logarithmic growth by C. violaceum and Acetobacter sp. and during late log growth on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41afd23efdc6ea6726f6d1fefb919775
https://doi.org/10.1128/aac.21.4.558
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5
High-pressure liquid chromatographic analysis of aztreonam in sera and urine
Autor: B J Remsburg, F G Pilkiewicz, R B Sykes, S M Fisher
Publikováno v: Antimicrobial Agents and Chemotherapy. 23:852-856
Aztreonam (SQ 26,776) is a new synthetic monocyclic beta-lactam antibiotic which is specifically active against aerobic gram-negative bacteria. High-pressure liquid chromatographic (HPLC) systems were developed for the quantitative analysis of aztreo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002f64b9d720e78326136bdeefebed11
https://doi.org/10.1128/aac.23.6.852
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6
Cefuroxime, a New Cephalosporin Antibiotic: Activity In Vitro
Autor: R. B. Sykes, J. E. Thornton, Cynthia H. O'Callaghan, A. Griffiths
Publikováno v: Antimicrobial Agents and Chemotherapy. 9:511-519
Cefuroxime is a new broad-spectrum cephalosporin antibiotic with increased stability to β-lactamases. This stability, although no absolute in all cases, has the effect of widening the antibacterial spectrum of the compound so that many organisms res
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a765fbbfa8299d2bb0f0ee764c5228
https://doi.org/10.1128/aac.9.3.511
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8
Aerocyanidin, a new antibiotic produced by Chromobacterium violaceum
Autor: W L, Parker, M L, Rathnum, J H, Johnson, J S, Wells, P A, Principe, R B, Sykes
Publikováno v: The Journal of Antibiotics. 41:454-460
Aerocyanidin, a new antibiotic containing an isonitrile group, has been isolated from fermentations of Chromobacterium violaceum ATCC 53434. Structure 1 was assigned on the bais of spectroscopic characterization of the antibiotic and of a degradation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef084e3009e61676cfb0c85d08a199c
https://doi.org/10.7164/antibiotics.41.454
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9
The sensitivity of urinary isolates to cefuroxime, a new β-lactamase stable cephalosporin
Autor: Ruth Phillips, R. B. Sykes, A. Griffiths, A. P. Roberts
Publikováno v: Current Medical Research and Opinion. 7:5-13
The sensitivities to cefuroxime and cephaloridine were compared in 500 bacterial isolates from consecutive cases of urinary tract infection. In the first 200 organisms there was generally good correlation between the diameters of the zone of inhibiti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4836b5f0fd2a65940827bd8216f1663a
https://doi.org/10.1185/03007998009116508
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10
A Transmissible Resistance Element from a Strain of Pseudomonas aeruginosa Containing No Detectable Extrachromosomal DNA
Autor: R. B. Sykes, M. H. Richmond, J. Grinsted, Lewis C. Ingram, J. R. Saunders
Publikováno v: Journal of General Microbiology. 72:269-279
SUMMARY: Pseudomonas aeruginosa PS18(RP1) is resistant to carbenicillin, neomycin/kanamycin and tetracycline. This strain gave rise to a derivative: PS18(RP1-1), resistant only to carbenicillin. RP1 was transmissible from PS18(RP1) to other strains o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7441eea9f9a95642512e32018e205c19
https://doi.org/10.1099/00221287-72-2-269
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