Laser Microdissection for Species-agnostic Single-tissue Applications

Autor: David H. A. Fitch, R. Antonio Herrera, Raya S. Jallad, Karin Kiontke, Alyssa Woronik

Publikováno v: J Vis Exp

Single-cell methodologies have revolutionized the analysis of the transcriptomes of specific cell types. However, they often require species-specific genetic "toolkits," such as promoters driving tissue-specific expression of fluorescent proteins. Fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262c87662a8e7606de245ac6c2a2e817
https://europepmc.org/articles/PMC9976942/

The Long Non-Coding RNA lep-5 Promotes the Juvenile-to-Adult Transition by Destabilizing LIN-28

Autor: Edward Vuong, Jintao Luo, David H. A. Fitch, Karin Kiontke, R. Antonio Herrera, Douglas S. Portman, Erich M. Schwarz

Publikováno v: Dev Cell

Summary Biological roles for most long non-coding RNAs (lncRNAs) remain mysterious. Here, using forward genetics, we identify lep-5, a lncRNA acting in the C. elegans heterochronic (developmental timing) pathway. Loss of lep-5 delays hypodermal matur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67bbd5718852843e15893315ccaa226c
https://doi.org/10.1016/j.devcel.2019.03.003

Makorin ortholog LEP-2 regulates LIN-28 stability to promote the juvenile-to-adult transition in Caenorhabditis elegans

Autor: R Antonio, Herrera, Karin, Kiontke, David H A, Fitch

Publikováno v: Development (Cambridge, England). 143(5)

The heterochronic genes lin-28, let-7 and lin-41 regulate fundamental developmental transitions in animals, such as stemness versus differentiation and juvenile versus adult states. We identify a new heterochronic gene, lep-2, in Caenorhabditis elega

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::acdc4a26a45e7abaf66642112a7781f2
https://pubmed.ncbi.nlm.nih.gov/26811380

Analysis of and Expression of Connexin 26 Mutations

Autor: Hamid R. Djalilian, R. Antonio Herrera, Nalin M. Kumar, Jason G. Cundiff, Venessa Rothholtz

Publikováno v: Otolaryngology–Head and Neck Surgery. 131

Problem: Mutations in the gap junction beta-2 (GJB2) gene, which encodes the connexin 26 protein, account for 50% of all the patients with autosomal recessive nonsyndromic hearing loss. Connexins are proteins that oligomerize to form a gap junction c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17d7b23c3cf2b4a227ffce51cacf060b
https://doi.org/10.1016/j.otohns.2004.06.138

Identificación y caracterización de Aeromonas sp patógenas aisladas de truchas arcoíris (Oncorhynchus mykiss) clínicamente enfermas cultivadas en piscigranjas del Perú

Autor: O. Mauro Estrella, E. Felipe Ramos, O. Jeferson Nuñure, A Adhemir Valera, S Alberto Manchego, C Nieves Sandoval, R Antonio Herrera

Publikováno v: Universidad Nacional Mayor de San Marcos
Revista de Investigaciones Veterinarias del Perú; Vol. 32 No. 4 (2021); e20927
Revista de Investigaciones Veterinarias del Perú; Vol. 32 Núm. 4 (2021); e20927

The present research aimed at the biochemical characterization and molecular identification of pathogenic strains of Aeromonas sp, isolated from juvenile rainbow trout with clinical signs compatible with aeromoniasis in six fish farms in Junín (2),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19c08ccb5e940f9e78c7169d1741bea
https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/20927