Zobrazeno 1 - 10
of 215
pro vyhledávání: '"R. Alric"'
Publikováno v:
Journal of Chromatography B. 766:181-187
Simultaneous measurement of isoniazid and its main acetylated metabolite acetylisoniazid in human plasma is realized by high-performance liquid chromatography. The technique used is evaluated by a factorial design of validation that proved to be conv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f41d55be59c0adb8dab94c501d8ccbf
https://doi.org/10.1016/s0378-4347(01)00434-0
https://doi.org/10.1016/s0378-4347(01)00434-0
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 698:225-233
(A) An analysis-of-variance spreadsheet program is presented which allows to readily test and/or quantitate in a single run analytical linearity, matrix effect on recovery, repeatability of measurement and of extraction and the ruggedness of these fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1018d0e91a3d5a7e32a2062c2a2e20
https://doi.org/10.1016/s0378-4347(97)00266-1
https://doi.org/10.1016/s0378-4347(97)00266-1
Publikováno v:
Therapeutic Drug Monitoring. 17:348-355
Therapeutic drug monitoring (TDM) of chronic treatments is justified for several reasons, including relative over- or underdosage due to variable individual elimination, pharmacokinetic interactions in drug combinations, and noncompliance. In all the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f354aa7b900bb6e3a8e5a45380ceb47c
https://doi.org/10.1097/00007691-199508000-00006
https://doi.org/10.1097/00007691-199508000-00006
Publikováno v:
Journal of Pharmaceutical Sciences. 83:1461-1464
The pharmacokinetics of valproic acid after oral administration of sustained-release formulations were studied in 12 healthy volunteers. The objective of the present study was to find an appropriate mathematical model to describe the complex drug int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0176c7b312d3a4b59aafbc7486544926
https://doi.org/10.1002/jps.2600831019
https://doi.org/10.1002/jps.2600831019
Publikováno v:
Clinical Neuropharmacology. 17:236-242
The present study was designed to investigate the efficacy of clonazepam in neuroleptic-induced akathisia. Twelve patients were treated during 2 weeks with clonazepam or placebo in a double-blind randomized design. Akathisia was scored by an independ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c4638494d11b47bfd8ce4eda693ec2
https://doi.org/10.1097/00002826-199406000-00003
https://doi.org/10.1097/00002826-199406000-00003
Autor:
Pierre Petit, A. Sluzewska, B. Hue, M. Cociglio, R. Pouget, R. Lonjon, R. Alric, J. P. Blayac
Publikováno v:
European Journal of Clinical Pharmacology. 41:541-546
The study was designed to investigate the antimanic profile of carbamazepine as a first-line drug in affective or schizoaffective disorders, to correlate the clinical efficacy with the plasma level of carbamazepine and its 10,11-epoxide metabolite, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8125b583f1087da9a208e5a29dd88ad6
https://doi.org/10.1007/bf00314982
https://doi.org/10.1007/bf00314982
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 572:269-276
A reversed-phase column liquid chromatographic assay is described and validated for lamotrigine, a new anticonvulsant drug. The drug and its internal standard were extracted from plasma into acetonitrile according to a previously described solvent-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d2628ef4badff9d52fea194171fc4d
https://doi.org/10.1016/0378-4347(91)80491-t
https://doi.org/10.1016/0378-4347(91)80491-t
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 16:275-280
The pharmacokinetics of apyramide, an ester of indomethacin and acetaminophen (paracetamol), were determined after intravenous administration to nine beagle dogs. Indomethacin and its pro-drug, apyramide, were extracted from acetonitrile-precipitated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f02465a801bd8f250fac3fe832298c0
https://doi.org/10.1007/bf03189972
https://doi.org/10.1007/bf03189972
Publikováno v:
Journal of chromatographic science. 41(2)
A rapid and simple high-performance liquid chromatographic method without internal standardization is evaluated for the drug-level monitoring of most marketed antiproteases and efavirenz. Following plasma deproteinization with acetonitrile, the analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a573c81cd1cad0e753c0ba71040cff
https://pubmed.ncbi.nlm.nih.gov/12639255
https://pubmed.ncbi.nlm.nih.gov/12639255
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 705(1)
Deproteinization of plasma samples with acetonitrile followed by coextracting acetonitrile and lipophilic solutes with chloroform, as already proposed for methotrexate, is stressed as a general sample cleanup procedure for liquid chromatography of hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22410ea4463db1cec6e8c45e8944fc71
https://pubmed.ncbi.nlm.nih.gov/9498673
https://pubmed.ncbi.nlm.nih.gov/9498673